Entity Details

Primary name Fgfr1
Entity type gene
Source Source Link

Details

PrimaryID14182
RefseqGene
SymbolFgfr1
Namefibroblast growth factor receptor 1
Chromosome8
Location8 14.12 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsFGFR1_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001525 angiogenesis
GO:0001657 ureteric bud development
GO:0001701 in utero embryonic development
GO:0001759 organ induction
GO:0001837 epithelial to mesenchymal transition
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0002062 chondrocyte differentiation
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005007 fibroblast growth factor-activated receptor activity
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007420 brain development
GO:0007435 salivary gland morphogenesis
GO:0007605 sensory perception of sound
GO:0008201 heparin binding
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010468 regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010763 positive regulation of fibroblast migration
GO:0010863 positive regulation of phospholipase C activity
GO:0010966 regulation of phosphate transport
GO:0010976 positive regulation of neuron projection development
GO:0017134 fibroblast growth factor binding
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019827 stem cell population maintenance
GO:0021769 orbitofrontal cortex development
GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration
GO:0021847 ventricular zone neuroblast division
GO:0021954 central nervous system neuron development
GO:0030324 lung development
GO:0030326 embryonic limb morphogenesis
GO:0030901 midbrain development
GO:0031175 neuron projection development
GO:0031410 cytoplasmic vesicle
GO:0033674 positive regulation of kinase activity
GO:0035607 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
GO:0042127 regulation of cell population proliferation
GO:0042169 SH2 domain binding
GO:0042472 inner ear morphogenesis
GO:0042473 outer ear morphogenesis
GO:0042474 middle ear morphogenesis
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043235 receptor complex
GO:0043406 positive regulation of MAP kinase activity
GO:0043410 positive regulation of MAPK cascade
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0043583 ear development
GO:0044877 protein-containing complex binding
GO:0045597 positive regulation of cell differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045787 positive regulation of cell cycle
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046777 protein autophosphorylation
GO:0048339 paraxial mesoderm development
GO:0048378 regulation of lateral mesodermal cell fate specification
GO:0048469 cell maturation
GO:0048471 perinuclear region of cytoplasm
GO:0048514 blood vessel morphogenesis
GO:0048699 generation of neurons
GO:0048762 mesenchymal cell differentiation
GO:0050729 positive regulation of inflammatory response
GO:0050839 cell adhesion molecule binding
GO:0051174 regulation of phosphorus metabolic process
GO:0051897 positive regulation of protein kinase B signaling
GO:0051930 regulation of sensory perception of pain
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060117 auditory receptor cell development
GO:0060445 branching involved in salivary gland morphogenesis
GO:0060484 lung-associated mesenchyme development
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0060979 vasculogenesis involved in coronary vascular morphogenesis
GO:0070640 vitamin D3 metabolic process
GO:0072091 regulation of stem cell proliferation
GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:0090272 negative regulation of fibroblast growth factor production
GO:0090722 receptor-receptor interaction
GO:1903465 positive regulation of mitotic cell cycle DNA replication
GO:1905564 positive regulation of vascular endothelial cell proliferation
GO:2000491 positive regulation of hepatic stellate cell activation
GO:2000546 positive regulation of endothelial cell chemotaxis to fibroblast growth factor
GO:2000830 positive regulation of parathyroid hormone secretion
GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand

Diseases

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Interactions

42 interactions

InteractorPartnerSourcesPublicationsLink
Fgfr1Frs2BioGRID15513912 17901128 details
Fgfr1GZMBBioGRID16798735 details
Fgfr1Fgf2BioGRID18337405 details
Fgfr1NostrinMINT22751148 details
Fgfr1KlbBioGRID, DIP17452648 17623664 32325033 details
Fgfr1KlBioGRID, DIP16436388 19966287 32325033 details
Fgfr1Fgf23BioGRID16436388 32325033 details
Fgfr1Flrt1BioGRID16872596 details
Fgfr1Flrt2BioGRID16872596 details
Fgfr1Flrt3BioGRID16872596 details
Fgfr1Frs3BioGRID17901128 details
Fgfr1GRB2BioGRID11729184 details
Fgfr1CrklBioGRID19307307 details
Fgfr1Dock1BioGRID19307307 details
Fgfr1IL17RDBioGRID12958313 details
Fgfr1Mapk8ip3BioGRID21156008 details
Fgfr1HDLBPBioGRID, IntAct26496610 details
Fgfr1HOMEZBioGRID, IntAct26496610 details
Fgfr1Fgf21DIP17452648 details
Fgfr1FGF23DIP19966287 details
Fgfr1Cacna1cIntAct24952909 details
Fgfr1METAP2BioGRID26496610 details
Fgfr1AlkBioGRID32325033 details
Fgfr1BtkBioGRID32325033 details
Fgfr1Erbb3BioGRID32325033 details
Fgfr1FesBioGRID32325033 details
Fgfr1Bnip2BioGRID32325033 details
Fgfr1Fgf4BioGRID32325033 details
Fgfr1KitBioGRID32325033 details
Fgfr1Fgfr2BioGRID32325033 details
Fgfr1Flt1BioGRID32325033 details
Fgfr1Flt4BioGRID32325033 details
Fgfr1Grb14BioGRID32325033 details
Fgfr1MatkBioGRID32325033 details
Fgfr1MertkBioGRID32325033 details
Fgfr1Mst1rBioGRID32325033 details
Fgfr1Ntrk1BioGRID32325033 details
Fgfr1Ptk7BioGRID32325033 details
Fgfr1RetBioGRID32325033 details
Fgfr1Ror1BioGRID32325033 details
Fgfr1TecBioGRID32325033 details
Fgfr1TxkBioGRID32325033 details