Entity Details

Primary name Fgr
Entity type gene
Source Source Link

Details

PrimaryID14191
RefseqGene
SymbolFgr
NameFGR proto-oncogene, Src family tyrosine kinase
Chromosome4
Location4 66.11 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsFGR_MOUSE

GO terms

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GOName
GO:0001784 phosphotyrosine residue binding
GO:0001819 positive regulation of cytokine production
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005743 mitochondrial inner membrane
GO:0005758 mitochondrial intermembrane space
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007229 integrin-mediated signaling pathway
GO:0008360 regulation of cell shape
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016235 aggresome
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019901 protein kinase binding
GO:0030154 cell differentiation
GO:0030282 bone mineralization
GO:0030335 positive regulation of cell migration
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0032587 ruffle membrane
GO:0032815 negative regulation of natural killer cell activation
GO:0032956 regulation of actin cytoskeleton organization
GO:0034987 immunoglobulin receptor binding
GO:0034988 Fc-gamma receptor I complex binding
GO:0043306 positive regulation of mast cell degranulation
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0045087 innate immune response
GO:0045088 regulation of innate immune response
GO:0045859 regulation of protein kinase activity
GO:0046777 protein autophosphorylation
GO:0048705 skeletal system morphogenesis
GO:0050764 regulation of phagocytosis
GO:0050830 defense response to Gram-positive bacterium

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
FgrClnkMINT16439675 details
FgrSykMINT11672534 details
FgrCblBioGRID7517397 9687507 details
FgrItgb1MINT19903482 details
FgrFancd2BioGRID28378742 details