Entity Details

Primary name Srgap2
Entity type gene
Source Source Link

Details

PrimaryID14270
RefseqGene
SymbolSrgap2
NameSLIT-ROBO Rho GTPase activating protein 2
Chromosome1
Location1
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSRGP2_MOUSE

GO terms

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GOName
GO:0003363 lamellipodium assembly involved in ameboidal cell migration
GO:0005096 GTPase activator activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005743 mitochondrial inner membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0014069 postsynaptic density
GO:0021816 extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
GO:0030027 lamellipodium
GO:0030336 negative regulation of cell migration
GO:0031267 small GTPase binding
GO:0034446 substrate adhesion-dependent cell spreading
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043547 positive regulation of GTPase activity
GO:0044327 dendritic spine head
GO:0045211 postsynaptic membrane
GO:0045335 phagocytic vesicle
GO:0046847 filopodium assembly
GO:0048812 neuron projection morphogenesis
GO:0051014 actin filament severing
GO:0060996 dendritic spine development
GO:2001223 negative regulation of neuron migration

Diseases

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Interactions

50 interactions

InteractorPartnerSourcesPublicationsLink
Srgap2CDC42BioGRID32203420 details
Srgap2RAC1BioGRID32203420 details
Srgap2SRGAP1IntAct32203420 details
Srgap2Lnx2BioGRID27889896 details
Srgap2Lnx1BioGRID27889896 details
Srgap2Herc2BioGRID, IntAct28671696 details
Srgap2Syngap1BioGRID, IntAct28706196 32325033 details
Srgap2SCOCBioGRID, IntAct32203420 details
Srgap2Anks1bMINT31388001 details
Srgap2YwhaeBioGRID16944949 details
Srgap2Fgd4BioGRID32325033 details
Srgap2Gnai3BioGRID32325033 details
Srgap2Ivns1abpBioGRID32325033 details
Srgap2LpxnBioGRID32325033 details
Srgap2Rapgef4BioGRID32325033 details
Srgap2Srgap1BioGRID32325033 details
Srgap2Arhgap15BioGRID32325033 details
Srgap2Arhgap19BioGRID32325033 details
Srgap2Arhgap21BioGRID32325033 details
Srgap2Arhgap26BioGRID32325033 details
Srgap2Arhgap35BioGRID32325033 details
Srgap2Arhgap40BioGRID32325033 details
Srgap2Arhgap42BioGRID32325033 details
Srgap2Chn2BioGRID32325033 details
Srgap2Cyp2a12BioGRID32325033 details
Srgap2DnmbpBioGRID32325033 details
Srgap2Dock1BioGRID32325033 details
Srgap2Gli1BioGRID32325033 details
Srgap2Gli2BioGRID32325033 details
Srgap2GnalBioGRID32325033 details
Srgap2GnasBioGRID32325033 details
Srgap2Lhx5BioGRID32325033 details
Srgap2Pdlim5BioGRID32325033 details
Srgap2Prickle1BioGRID32325033 details
Srgap2Prickle2BioGRID32325033 details
Srgap2Ralbp1BioGRID32325033 details
Srgap2Rasgef1bBioGRID32325033 details
Srgap2Slc26a7BioGRID32325033 details
Srgap2Slc7a2BioGRID32325033 details
Srgap2SlmapBioGRID32325033 details
Srgap2Sorbs1BioGRID32325033 details
Srgap2Sorbs2BioGRID32325033 details
Srgap2SpoplBioGRID32325033 details
Srgap2Syne2BioGRID32325033 details
Srgap2Timm44BioGRID32325033 details
Srgap2Vav1BioGRID32325033 details
Srgap2Stard13BioGRID32325033 details
Srgap2Tomm70aBioGRID32325033 details
Srgap2Tnk2BioGRID29254152 details
Srgap2KPRPBioGRID32203420 details