Entity Details

Primary name Fxn
Entity type gene
Source Source Link

Details

PrimaryID14297
RefseqGene
SymbolFxn
Namefrataxin
Chromosome19
Location19
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsFRDA_MOUSE

GO terms

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GOName
GO:0004322 ferroxidase activity
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006119 oxidative phosphorylation
GO:0006783 heme biosynthetic process
GO:0006811 ion transport
GO:0006879 cellular iron ion homeostasis
GO:0007005 mitochondrion organization
GO:0007628 adult walking behavior
GO:0008198 ferrous iron binding
GO:0008199 ferric iron binding
GO:0008284 positive regulation of cell population proliferation
GO:0009060 aerobic respiration
GO:0009792 embryo development ending in birth or egg hatching
GO:0010039 response to iron ion
GO:0010722 regulation of ferrochelatase activity
GO:0016226 iron-sulfur cluster assembly
GO:0016540 protein autoprocessing
GO:0018283 iron incorporation into metallo-sulfur cluster
GO:0019230 proprioception
GO:0019899 enzyme binding
GO:0030307 positive regulation of cell growth
GO:0034986 iron chaperone activity
GO:0040015 negative regulation of multicellular organism growth
GO:0043066 negative regulation of apoptotic process
GO:0043085 positive regulation of catalytic activity
GO:0045773 positive regulation of axon extension
GO:0046621 negative regulation of organ growth
GO:0051349 positive regulation of lyase activity
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0070301 cellular response to hydrogen peroxide
GO:0090201 negative regulation of release of cytochrome c from mitochondria
GO:1904231 positive regulation of succinate dehydrogenase activity
GO:1904234 positive regulation of aconitate hydratase activity
GO:1990221 L-cysteine desulfurase complex

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
FxnHspa9BioGRID32325033 details
FxnPmpcbBioGRID32325033 details
FxnHspd1BioGRID32325033 details
FxnLyrm4BioGRID32325033 details
FxnSdhaBioGRID32325033 details