Entity Details

Primary name Tlr3
Entity type gene
Source Source Link

Details

PrimaryID142980
RefseqGene
SymbolTlr3
Nametoll-like receptor 3
Chromosome8
Location8
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-01-21
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsTLR3_MOUSE

GO terms

Show/Hide Table
GOName
GO:0001774 microglial cell activation
GO:0002224 toll-like receptor signaling pathway
GO:0002730 regulation of dendritic cell cytokine production
GO:0002756 MyD88-independent toll-like receptor signaling pathway
GO:0003725 double-stranded RNA binding
GO:0004888 transmembrane signaling receptor activity
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005789 endoplasmic reticulum membrane
GO:0005887 integral component of plasma membrane
GO:0006952 defense response
GO:0006954 inflammatory response
GO:0007252 I-kappaB phosphorylation
GO:0008584 male gonad development
GO:0009615 response to virus
GO:0009986 cell surface
GO:0010008 endosome membrane
GO:0010628 positive regulation of gene expression
GO:0032481 positive regulation of type I interferon production
GO:0032722 positive regulation of chemokine production
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0032729 positive regulation of interferon-gamma production
GO:0032735 positive regulation of interleukin-12 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0034123 positive regulation of toll-like receptor signaling pathway
GO:0034138 toll-like receptor 3 signaling pathway
GO:0034346 positive regulation of type III interferon production
GO:0035458 cellular response to interferon-beta
GO:0035690 cellular response to drug
GO:0038023 signaling receptor activity
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 response to exogenous dsRNA
GO:0043331 response to dsRNA
GO:0045087 innate immune response
GO:0045766 positive regulation of angiogenesis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046330 positive regulation of JNK cascade
GO:0050729 positive regulation of inflammatory response
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051607 defense response to virus
GO:0071260 cellular response to mechanical stimulus
GO:0071346 cellular response to interferon-gamma
GO:0071360 cellular response to exogenous dsRNA
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097527 necroptotic signaling pathway
GO:1901224 positive regulation of NIK/NF-kappaB signaling

Diseases

Show/Hide Table