Entity Details

Primary name Fyn
Entity type gene
Source Source Link

Details

PrimaryID14360
RefseqGene
SymbolFyn
NameFyn proto-oncogene
Chromosome10
Location10 20.51 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsFYN_MOUSE

GO terms

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GOName
GO:0000304 response to singlet oxygen
GO:0001664 G protein-coupled receptor binding
GO:0001764 neuron migration
GO:0002250 adaptive immune response
GO:0003015 heart process
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005768 endosome
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0007166 cell surface receptor signaling pathway
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008360 regulation of cell shape
GO:0010629 negative regulation of gene expression
GO:0010730 negative regulation of hydrogen peroxide biosynthetic process
GO:0010976 positive regulation of neuron projection development
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014069 postsynaptic density
GO:0015631 tubulin binding
GO:0016004 phospholipase activator activity
GO:0016020 membrane
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019899 enzyme binding
GO:0030154 cell differentiation
GO:0030425 dendrite
GO:0030900 forebrain development
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031397 negative regulation of protein ubiquitination
GO:0031802 type 5 metabotropic glutamate receptor binding
GO:0035556 intracellular signal transduction
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0042177 negative regulation of protein catabolic process
GO:0042493 response to drug
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042542 response to hydrogen peroxide
GO:0042552 myelination
GO:0042608 T cell receptor binding
GO:0042609 CD4 receptor binding
GO:0042610 CD8 receptor binding
GO:0042802 identical protein binding
GO:0043014 alpha-tubulin binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043231 intracellular membrane-bounded organelle
GO:0043274 phospholipase binding
GO:0043524 negative regulation of neuron apoptotic process
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0044297 cell body
GO:0044325 transmembrane transporter binding
GO:0044877 protein-containing complex binding
GO:0045087 innate immune response
GO:0045121 membrane raft
GO:0045471 response to ethanol
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0046875 ephrin receptor binding
GO:0048156 tau protein binding
GO:0048471 perinuclear region of cytoplasm
GO:0048813 dendrite morphogenesis
GO:0050730 regulation of peptidyl-tyrosine phosphorylation
GO:0050798 activated T cell proliferation
GO:0050804 modulation of chemical synaptic transmission
GO:0050852 T cell receptor signaling pathway
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
GO:0051428 peptide hormone receptor binding
GO:0070851 growth factor receptor binding
GO:0071375 cellular response to peptide hormone stimulus
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0071944 cell periphery
GO:0090314 positive regulation of protein targeting to membrane
GO:0097038 perinuclear endoplasmic reticulum
GO:0097386 glial cell projection
GO:0097718 disordered domain specific binding
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098978 glutamatergic synapse
GO:0099092 postsynaptic density, intracellular component
GO:1900182 positive regulation of protein localization to nucleus
GO:1900449 regulation of glutamate receptor signaling pathway
GO:1901216 positive regulation of neuron death
GO:1902951 negative regulation of dendritic spine maintenance
GO:1903202 negative regulation of oxidative stress-induced cell death
GO:1904645 response to amyloid-beta
GO:1904646 cellular response to amyloid-beta
GO:1905232 cellular response to L-glutamate
GO:1905430 cellular response to glycine
GO:1905664 regulation of calcium ion import across plasma membrane
GO:2001056 positive regulation of cysteine-type endopeptidase activity
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Diseases

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Interactions

57 interactions

InteractorPartnerSourcesPublicationsLink
FynSlamf1MINT11477403 12545173 16847311 details
FynKhdrbs1BioGRID, IntAct, UniProt10077576 10844001 15102471 details
FynBcar1BioGRID, IntAct15102471 17875741 details
FynRaver1IntAct15102471 details
FynDynlt1fIntAct15102471 details
FynDynlt1cIntAct15102471 details
FynDynlt1aIntAct15102471 details
FynDynlt1bIntAct15102471 details
FynPtk2BioGRID, IntAct15102471 17875741 details
FynUck2IntAct15102471 details
FynSphk2IntAct16316995 details
FynCBLMINT9890970 details
FynFZD2IntAct25417160 details
FynEno1BioGRID18854310 details
FynPtprfBioGRID18854310 details
FynEnahBioGRID8861907 details
FynFmn1BioGRID8605874 details
FynWasBioGRID14707117 details
FynCd36BioGRID25157091 details
FynDab1BioGRID16529723 details
FynSh2d1aMINT12545173 16847311 details
FynClnkMINT12681493 details
FynFybMINT12681493 details
FynSkap2MINT12681493 details
FynHcls1IntAct10713104 details
FynMED28IntAct16899217 details
FynMed28IntAct16899217 details
FynArhgap33IntAct16777849 details
FynPlcg2MINT8395016 details
FynPik3r1BioGRID, MINT8395016 9115297 details
FynCblBioGRID, IntAct, MINT19734451 27474268 8551236 8635998 9210408 9890970 details
FynPTPRTMINT19816407 details
FynCLIC5MINT10930415 details
FynAdd2MINT16765915 details
FynPdgfrbMINT7730365 details
FynCSF1RMINT7730365 details
FynCtla4MINT9712716 details
FynMAPTMINT21692989 details
FynPtpraMINT18948260 9535845 details
FynPTPRAMINT9535845 details
FynPLXNA2mbinfo12372285 details
FynCdk5mbinfo12372285 details
FynTmem47UniProt21881001 details
FynKhdrbs2UniProt10077576 details
FynCsf1rBioGRID15297464 details
FynDiaph1BioGRID18194650 details
FynSh2d1b2BioGRID16425036 details
FynKdrBioGRID16966330 details
FynNck1BioGRID16966330 details
FynPtpn5BioGRID27457929 details
FynYwhabIntAct16635246 details
FynNcoa2MINT14980517 details
FynSTAT3IntAct25417160 details
FynLatIntAct24584089 details
FynLcp2IntAct24584089 details
FynPag1IntAct26512138 details
FynPPT1MINT30918483 details