Entity Details

Primary name WASL_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ91YD9
EntryNameWASL_MOUSE
FullNameNeural Wiskott-Aldrich syndrome protein
TaxID10090
Evidenceevidence at protein level
Length501
SequenceStatuscomplete
DateCreated2005-02-01
DateModified2021-06-02

Ontological Relatives

GenesWasl

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0003779 actin binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005884 actin filament
GO:0006900 vesicle budding from membrane
GO:0008092 cytoskeletal protein binding
GO:0009617 response to bacterium
GO:0010324 membrane invagination
GO:0016050 vesicle organization
GO:0030027 lamellipodium
GO:0030036 actin cytoskeleton organization
GO:0030041 actin filament polymerization
GO:0030048 actin filament-based movement
GO:0030050 vesicle transport along actin filament
GO:0030478 actin cap
GO:0031252 cell leading edge
GO:0031410 cytoplasmic vesicle
GO:0032880 regulation of protein localization
GO:0034629 cellular protein-containing complex localization
GO:0042802 identical protein binding
GO:0045010 actin nucleation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050921 positive regulation of chemotaxis
GO:0051301 cell division
GO:0051491 positive regulation of filopodium assembly
GO:0051653 spindle localization
GO:0060491 regulation of cell projection assembly
GO:0060997 dendritic spine morphogenesis
GO:0097320 plasma membrane tubulation
GO:0098794 postsynapse
GO:0098974 postsynaptic actin cytoskeleton organization
GO:0098978 glutamatergic synapse
GO:1903526 negative regulation of membrane tubulation
GO:2000370 positive regulation of clathrin-dependent endocytosis
GO:2000402 negative regulation of lymphocyte migration
GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000095 CRIB domainDomainDomain
IPR000697 WH1/EVH1 domainDomainDomain
IPR003124 WH2 domainDomainDomain
IPR011026 Wiscott-Aldrich syndrome protein, C-terminalFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR030214 Neural Wiskott-Aldrich syndrome proteinFamilyFamily
IPR033927 WASP family, EVH1 domainDomainDomain
IPR036936 CRIB domain superfamilyFamilyHomologous superfamily

Diseases

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