Entity Details

Primary name EGLN2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ91YE2
EntryNameEGLN2_MOUSE
FullNameProlyl hydroxylase EGLN2
TaxID10090
Evidenceevidence at protein level
Length419
SequenceStatuscomplete
DateCreated2003-06-16
DateModified2021-06-02

Ontological Relatives

GenesEgln2

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0008198 ferrous iron binding
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0019826 oxygen sensor activity
GO:0031418 L-ascorbic acid binding
GO:0031543 peptidyl-proline dioxygenase activity
GO:0031545 peptidyl-proline 4-dioxygenase activity
GO:0043523 regulation of neuron apoptotic process
GO:0045454 cell redox homeostasis
GO:0045732 positive regulation of protein catabolic process
GO:0071456 cellular response to hypoxia

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR005123 Oxoglutarate/iron-dependent dioxygenaseDomainDomain
IPR006620 Prolyl 4-hydroxylase, alpha subunitDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
EGLN2_MOUSERBTN2_MOUSEBioGRID26764384 details
EGLN2_MOUSEHIF1A_MOUSEBioGRID23649506 details