Entity Details

Primary name Grin1
Entity type gene
Source Source Link

Details

PrimaryID14810
RefseqGene
SymbolGrin1
Nameglutamate receptor, ionotropic, NMDA1 (zeta 1)
Chromosome2
Location2 17.14 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsNMDZ1_MOUSE

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001661 conditioned taste aversion
GO:0001964 startle response
GO:0001967 suckling behavior
GO:0001975 response to amphetamine
GO:0004970 ionotropic glutamate receptor activity
GO:0004972 NMDA glutamate receptor activity
GO:0005102 signaling receptor binding
GO:0005261 cation channel activity
GO:0005262 calcium channel activity
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006812 cation transport
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0007268 chemical synaptic transmission
GO:0007611 learning or memory
GO:0007612 learning
GO:0007613 memory
GO:0007616 long-term memory
GO:0008021 synaptic vesicle
GO:0008306 associative learning
GO:0008344 adult locomotory behavior
GO:0008355 olfactory learning
GO:0008542 visual learning
GO:0009986 cell surface
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0010646 regulation of cell communication
GO:0010942 positive regulation of cell death
GO:0014069 postsynaptic density
GO:0015276 ligand-gated ion channel activity
GO:0016020 membrane
GO:0016594 glycine binding
GO:0016595 glutamate binding
GO:0017146 NMDA selective glutamate receptor complex
GO:0018964 propylene metabolic process
GO:0019233 sensory perception of pain
GO:0019899 enzyme binding
GO:0019902 phosphatase binding
GO:0021586 pons maturation
GO:0021987 cerebral cortex development
GO:0022843 voltage-gated cation channel activity
GO:0022849 glutamate-gated calcium ion channel activity
GO:0030425 dendrite
GO:0030426 growth cone
GO:0030658 transport vesicle membrane
GO:0030672 synaptic vesicle membrane
GO:0032590 dendrite membrane
GO:0035176 social behavior
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0035249 synaptic transmission, glutamatergic
GO:0035254 glutamate receptor binding
GO:0038023 signaling receptor activity
GO:0042165 neurotransmitter binding
GO:0042391 regulation of membrane potential
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0043083 synaptic cleft
GO:0043195 terminal bouton
GO:0043197 dendritic spine
GO:0043278 response to morphine
GO:0043523 regulation of neuron apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0043576 regulation of respiratory gaseous exchange
GO:0044307 dendritic branch
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0045471 response to ethanol
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048167 regulation of synaptic plasticity
GO:0048168 regulation of neuronal synaptic plasticity
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0048511 rhythmic process
GO:0048814 regulation of dendrite morphogenesis
GO:0050770 regulation of axonogenesis
GO:0050905 neuromuscular process
GO:0051290 protein heterotetramerization
GO:0051963 regulation of synapse assembly
GO:0055074 calcium ion homeostasis
GO:0060076 excitatory synapse
GO:0060079 excitatory postsynaptic potential
GO:0060134 prepulse inhibition
GO:0060179 male mating behavior
GO:0065003 protein-containing complex assembly
GO:0097060 synaptic membrane
GO:0097553 calcium ion transmembrane import into cytosol
GO:0098686 hippocampal mossy fiber to CA3 synapse
GO:0098688 parallel fiber to Purkinje cell synapse
GO:0098839 postsynaptic density membrane
GO:0098978 glutamatergic synapse
GO:0099056 integral component of presynaptic membrane
GO:0099061 integral component of postsynaptic density membrane
GO:0099507 ligand-gated ion channel activity involved in regulation of presynaptic membrane potential
GO:1900149 positive regulation of Schwann cell migration
GO:1902952 positive regulation of dendritic spine maintenance
GO:1903428 positive regulation of reactive oxygen species biosynthetic process
GO:1903539 protein localization to postsynaptic membrane
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
GO:1905429 response to glycine
GO:2000463 positive regulation of excitatory postsynaptic potential
GO:2001056 positive regulation of cysteine-type endopeptidase activity

Diseases

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Interactions

139 interactions

InteractorPartnerSourcesPublicationsLink
Grin1Dlg4BioGRID, DIP, IntAct, MINT10862698 15663482 16554481 16601687 16635246 19240213 19243221 19455133 23760271 27507650 28671696 9647694 details
Grin1Grin2bBioGRID, DIP, IntAct, MINT10862698 14645471 15663482 16554481 16635246 19243221 20141836 32033586 9003035 details
Grin1Grin2aBioGRID, DIP, IntAct, MINT10862698 14645471 15663482 16554481 16635246 17018287 19243221 30284099 9003035 details
Grin1Cdh2BioGRID, IntAct, MINT10862698 16635246 17589506 details
Grin1Calm1BioGRID, IntAct, MINT10862698 15663482 16635246 details
Grin1Myh10BioGRID, IntAct10862698 16635246 details
Grin1CltcBioGRID, IntAct10862698 16635246 details
Grin1Camk2aBioGRID, IntAct, MINT10862698 16635246 22234183 24734203 details
Grin1BsnBioGRID, IntAct10862698 16635246 details
Grin1PfklBioGRID, IntAct10862698 16635246 details
Grin1FusBioGRID, IntAct10862698 16635246 details
Grin1SlmapBioGRID, IntAct10862698 16635246 details
Grin1Trp53bp1BioGRID, IntAct10862698 16635246 details
Grin1InaBioGRID, IntAct10862698 16635246 details
Grin1Dlg1BioGRID, IntAct10862698 16635246 details
Grin1Appl1BioGRID, IntAct10862698 16635246 details
Grin1Tjp1BioGRID, IntAct10862698 16635246 details
Grin1Exoc7MINT16601687 details
Grin1Exoc3MINT16601687 details
Grin1Exoc4MINT16601687 details
Grin1Ephb2DIP21508957 details
Grin1Syngap1BioGRID, IntAct10862698 27507650 28671696 28706196 details
Grin1Akap5BioGRID10862698 details
Grin1Akap9BioGRID10862698 details
Grin1Rps6ka1BioGRID10862698 details
Grin1Rap1aBioGRID10862698 details
Grin1Pik3r1BioGRID10862698 details
Grin1Ctnnd1BioGRID10862698 details
Grin1Actc1BioGRID10862698 details
Grin1Spta1BioGRID10862698 details
Grin1Hspa8BioGRID10862698 details
Grin1Tuba4aBioGRID10862698 details
Grin1Tfap2aBioGRID15663482 details
Grin1NumbBioGRID17589506 details
Grin1Shc3BioGRID15716419 details
Grin1Eps8BioGRID17018287 details
Grin1Gria1BioGRID17018287 details
Grin1Lrp1BioGRID23760271 details
Grin1Ppp1r9bBioGRID28634551 30562941 details
Grin1Ctbp1BioGRID30284099 details
Grin1SrcBioGRID, IntAct, MINT10862698 16635246 details
Grin1Dlg3BioGRID, IntAct, MINT10862698 16635246 details
Grin1Ptk2bBioGRID, IntAct, MINT10862698 16635246 details
Grin1PrkceBioGRID, IntAct, MINT10862698 16635246 details
Grin1PrkcgBioGRID, IntAct, MINT10862698 16635246 details
Grin1PrkcbBioGRID, IntAct, MINT10862698 16635246 details
Grin1Camk2bBioGRID, IntAct, MINT10862698 16635246 details
Grin1Homer1BioGRID, IntAct, MINT10862698 16635246 details
Grin1Grm1BioGRID, IntAct, MINT10862698 16635246 details
Grin1PrkacaBioGRID, MINT10862698 details
Grin1Tuba1aBioGRID, IntAct, MINT10862698 16635246 details
Grin1Grin1MINT10862698 details
Grin1Myo5aIntAct, MINT10862698 16635246 details
Grin1Shank2BioGRID, IntAct, MINT10862698 16635246 details
Grin1ActbIntAct, MINT10862698 16635246 details
Grin1ItpkaMINT10862698 details
Grin1Dusp4BioGRID, IntAct, MINT10862698 16635246 details
Grin1Prkar2bBioGRID, IntAct, MINT10862698 16635246 details
Grin1Dlgap1BioGRID, IntAct, MINT10862698 16635246 27507650 28671696 details
Grin1Dlg2BioGRID, IntAct, MINT10862698 16635246 details
Grin1NsfBioGRID, IntAct, MINT10862698 16635246 details
Grin1ArcBioGRID, IntAct, MINT10862698 16635246 details
Grin1CttnBioGRID, IntAct, MINT10862698 16635246 details
Grin1Dsg1aBioGRID, IntAct, MINT10862698 16635246 details
Grin1Ctnnb1BioGRID, IntAct, MINT10862698 16635246 details
Grin1Map2BioGRID, IntAct, MINT10862698 16635246 details
Grin1Sptbn1IntAct, MINT10862698 16635246 details
Grin1Actn2BioGRID, IntAct, MINT10862698 16635246 details
Grin1Dnm1BioGRID, IntAct, MINT10862698 16635246 details
Grin1Nos1BioGRID, IntAct, MINT10862698 16635246 details
Grin1Raf1BioGRID, IntAct, MINT10862698 16635246 details
Grin1Rps6ka3BioGRID, IntAct, MINT10862698 16635246 details
Grin1Map2k2BioGRID, IntAct, MINT10862698 16635246 details
Grin1Map2k1BioGRID, IntAct, MINT10862698 16635246 details
Grin1Mapk1BioGRID, IntAct, MINT10862698 16635246 details
Grin1Mapk3BioGRID, IntAct, MINT10862698 16635246 details
Grin1Pla2g4aBioGRID, IntAct, MINT10862698 16635246 details
Grin1Plcg1BioGRID, IntAct, MINT10862698 16635246 details
Grin1Ppp1ccBioGRID, MINT10862698 details
Grin1Calm2IntAct, MINT10862698 16635246 details
Grin1Calm3IntAct, MINT10862698 16635246 details
Grin1Hspa1bBioGRID, IntAct, MINT10862698 16635246 details
Grin1Nf1BioGRID, IntAct, MINT10862698 16635246 details
Grin1CitBioGRID, IntAct, MINT10862698 16635246 details
Grin1Rap2aIntAct, MINT10862698 16635246 details
Grin1Rac1BioGRID, IntAct, MINT10862698 16635246 details
Grin1Ptpn11BioGRID, IntAct, MINT10862698 16635246 details
Grin1Ppp5cBioGRID, IntAct, MINT10862698 16635246 details
Grin1Ppp3caBioGRID, IntAct, MINT10862698 16635246 details
Grin1Ppp2caBioGRID, MINT10862698 details
Grin1Plcb1IntAct, MINT10862698 16635246 details
Grin1YwhabIntAct16635246 details
Grin1Mapk10IntAct16635246 details
Grin1Myo1bIntAct16635246 details
Grin1Myh9IntAct16635246 details
Grin1Syngr1IntAct16635246 details
Grin1Stx1aIntAct16635246 details
Grin1Cse1lIntAct16635246 details
Grin1Pik3caIntAct16635246 details
Grin1Cacng2IntAct16635246 details
Grin1Irs1IntAct16635246 details
Grin1ArntIntAct16635246 details
Grin1BadIntAct16635246 details
Grin1KalrnIntAct16635246 28706196 details
Grin1Gap43IntAct16635246 details
Grin1Fgd4IntAct16635246 details
Grin1RanIntAct16635246 details
Grin1RalaIntAct16635246 details
Grin1Rab3aIntAct16635246 details
Grin1Rab27aIntAct16635246 details
Grin1Rab11aIntAct16635246 details
Grin1HrasIntAct16635246 details
Grin1Ptpn5IntAct16635246 details
Grin1Ptpn1IntAct16635246 details
Grin1PrkacbIntAct16635246 details
Grin1Prkar1aIntAct16635246 details
Grin1Prkar1bIntAct16635246 details
Grin1Pdpk1IntAct16635246 details
Grin1Map2k7IntAct16635246 details
Grin1Map2k3IntAct16635246 details
Grin1Gsk3bIntAct16635246 details
Grin1Akt2IntAct16635246 details
Grin1YwhagIntAct16635246 details
Grin1YwhaeIntAct16635246 details
Grin1Rack1IntAct16635246 details
Grin1Mapk8ip1IntAct16635246 details
Grin1Grb2IntAct16635246 details
Grin1Atg16l1IntAct16635246 details
Grin1DlatIntAct16635246 details
Grin1Paxbp1IntAct16635246 details
Grin1Atp1a1IntAct16635246 details
Grin1Ppp2r1aIntAct16635246 details
Grin1Atp1a3IntAct16635246 details
Grin1FlncIntAct16635246 details
Grin1Dapk1IntAct20141836 details
Grin1Neto1DIP19243221 details
Grin1TnikBioGRID, IntAct28671696 details
Grin1Shank3BioGRID, IntAct27507650 28671696 details
Grin1Agap2BioGRID, IntAct28706196 details