Entity Details

Primary name Grin2b
Entity type gene
Source Source Link

Details

PrimaryID14812
RefseqGene
SymbolGrin2b
Nameglutamate receptor, ionotropic, NMDA2B (epsilon 2)
Chromosome6
Location6 66.38 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsNMDE2_MOUSE

GO terms

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GOName
GO:0001508 action potential
GO:0001662 behavioral fear response
GO:0001666 response to hypoxia
GO:0001701 in utero embryonic development
GO:0001964 startle response
GO:0001967 suckling behavior
GO:0004970 ionotropic glutamate receptor activity
GO:0004972 NMDA glutamate receptor activity
GO:0005102 signaling receptor binding
GO:0005149 interleukin-1 receptor binding
GO:0005234 extracellularly glutamate-gated ion channel activity
GO:0005261 cation channel activity
GO:0005262 calcium channel activity
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005770 late endosome
GO:0005789 endoplasmic reticulum membrane
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006812 cation transport
GO:0006816 calcium ion transport
GO:0007268 chemical synaptic transmission
GO:0007423 sensory organ development
GO:0007611 learning or memory
GO:0007612 learning
GO:0007613 memory
GO:0008013 beta-catenin binding
GO:0008021 synaptic vesicle
GO:0008270 zinc ion binding
GO:0008306 associative learning
GO:0009986 cell surface
GO:0010243 response to organonitrogen compound
GO:0010738 regulation of protein kinase A signaling
GO:0010942 positive regulation of cell death
GO:0014049 positive regulation of glutamate secretion
GO:0014069 postsynaptic density
GO:0015276 ligand-gated ion channel activity
GO:0016020 membrane
GO:0016594 glycine binding
GO:0016595 glutamate binding
GO:0017146 NMDA selective glutamate receptor complex
GO:0022849 glutamate-gated calcium ion channel activity
GO:0030018 Z disc
GO:0030658 transport vesicle membrane
GO:0031749 D2 dopamine receptor binding
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0035255 ionotropic glutamate receptor binding
GO:0036094 small molecule binding
GO:0038023 signaling receptor activity
GO:0042165 neurotransmitter binding
GO:0042596 fear response
GO:0042734 presynaptic membrane
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043083 synaptic cleft
GO:0043113 receptor clustering
GO:0043195 terminal bouton
GO:0043197 dendritic spine
GO:0043408 regulation of MAPK cascade
GO:0044307 dendritic branch
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0045471 response to ethanol
GO:0046960 sensitization
GO:0048167 regulation of synaptic plasticity
GO:0048168 regulation of neuronal synaptic plasticity
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0048266 behavioral response to pain
GO:0048511 rhythmic process
GO:0050806 positive regulation of synaptic transmission
GO:0050839 cell adhesion molecule binding
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
GO:0051290 protein heterotetramerization
GO:0060078 regulation of postsynaptic membrane potential
GO:0060079 excitatory postsynaptic potential
GO:0060291 long-term synaptic potentiation
GO:0097060 synaptic membrane
GO:0097110 scaffold protein binding
GO:0097440 apical dendrite
GO:0097553 calcium ion transmembrane import into cytosol
GO:0098686 hippocampal mossy fiber to CA3 synapse
GO:0098688 parallel fiber to Purkinje cell synapse
GO:0098794 postsynapse
GO:0098839 postsynaptic density membrane
GO:0098978 glutamatergic synapse
GO:0098989 NMDA selective glutamate receptor signaling pathway
GO:0099056 integral component of presynaptic membrane
GO:0099061 integral component of postsynaptic density membrane
GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration
GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
GO:1901216 positive regulation of neuron death
GO:1902951 negative regulation of dendritic spine maintenance
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
GO:2001056 positive regulation of cysteine-type endopeptidase activity

Diseases

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Interactions

198 interactions

InteractorPartnerSourcesPublicationsLink
Grin2bDlg4BioGRID, DIP, IntAct, MINT10862698 15663482 16332682 16554481 16635246 16710293 17950729 19240213 19243221 19455133 20141836 20467438 22234183 23760271 27507650 28671696 9647694 details
Grin2bDapk1IntAct20141836 details
Grin2bPatjBioGRID9647694 details
Grin2bGrin1BioGRID, DIP, IntAct, MINT10862698 14645471 15663482 16554481 16635246 19243221 20141836 32033586 9003035 details
Grin2bActn2BioGRID, IntAct, MINT10862698 16635246 16710293 details
Grin2bCamk2aBioGRID, IntAct, MINT10862698 16635246 16710293 20141836 22234183 24725413 24734203 details
Grin2bGrin2aBioGRID, IntAct, MINT10862698 14645471 16554481 16635246 details
Grin2bCltcBioGRID, IntAct10862698 16635246 details
Grin2bMap2BioGRID, IntAct10862698 16635246 details
Grin2bCdh2BioGRID, IntAct10862698 16635246 details
Grin2bDsg1aBioGRID, IntAct10862698 16635246 details
Grin2bShank2BioGRID, IntAct10862698 16635246 details
Grin2bCttnBioGRID, IntAct10862698 16635246 details
Grin2bCtnnb1BioGRID, IntAct10862698 16635246 details
Grin2bPlcg1BioGRID, IntAct10862698 16635246 details
Grin2bNos1BioGRID, IntAct10862698 16635246 details
Grin2bPla2g4aBioGRID, IntAct10862698 16635246 details
Grin2bCalm1BioGRID, IntAct10862698 16635246 details
Grin2bArcBioGRID, IntAct10862698 16635246 details
Grin2bNf1BioGRID, IntAct10862698 16635246 details
Grin2bCitBioGRID, IntAct10862698 16635246 details
Grin2bRalaBioGRID, IntAct10862698 16635246 details
Grin2bRac1BioGRID, IntAct10862698 16635246 details
Grin2bHrasBioGRID, IntAct10862698 16635246 details
Grin2bPtpn5BioGRID, IntAct16635246 27457929 details
Grin2bPpp5cBioGRID, IntAct10862698 16635246 details
Grin2bSrcBioGRID, IntAct10862698 16635246 details
Grin2bPtk2bBioGRID, IntAct10862698 16635246 details
Grin2bRps6ka3BioGRID, IntAct10862698 16635246 details
Grin2bRaf1BioGRID, IntAct10862698 16635246 details
Grin2bPrkcgBioGRID, IntAct10862698 16635246 details
Grin2bPrkceBioGRID, IntAct10862698 16635246 details
Grin2bPrkcbBioGRID, IntAct10862698 16635246 details
Grin2bPrkar2bBioGRID, IntAct10862698 16635246 details
Grin2bDusp4BioGRID, IntAct10862698 16635246 details
Grin2bMap2k2BioGRID, IntAct10862698 16635246 details
Grin2bMap2k1BioGRID, IntAct10862698 16635246 details
Grin2bMapk1BioGRID, IntAct10862698 16635246 details
Grin2bMapk3BioGRID, IntAct10862698 16635246 details
Grin2bHomer1BioGRID, IntAct10862698 16635246 details
Grin2bPpp2caBioGRID, IntAct10862698 16635246 details
Grin2bAp2a1MINT16710293 details
Grin2bSyngap1BioGRID, IntAct10862698 27507650 28671696 28706196 details
Grin2bArhgap32BioGRID12531901 details
Grin2bAkap9BioGRID10862698 details
Grin2bAkap5BioGRID10862698 details
Grin2bPrkacaBioGRID10862698 details
Grin2bPpp1ccBioGRID10862698 details
Grin2bRps6ka1BioGRID10862698 details
Grin2bRap1aBioGRID10862698 details
Grin2bPik3r1BioGRID10862698 details
Grin2bCtnnd1BioGRID10862698 details
Grin2bActc1BioGRID10862698 details
Grin2bSpta1BioGRID10862698 details
Grin2bLin7cBioGRID16186258 details
Grin2bShc2BioGRID15716419 details
Grin2bShc3BioGRID15716419 details
Grin2bLrp1BioGRID23760271 details
Grin2bPpp1r9bBioGRID30562941 details
Grin2bPde10aBioGRID25762721 details
Grin2bNsfBioGRID, IntAct, MINT10862698 16635246 details
Grin2bDnm1BioGRID, IntAct, MINT10862698 16635246 details
Grin2bHspa1bBioGRID, IntAct, MINT10862698 16635246 details
Grin2bPtpn11BioGRID, IntAct, MINT10862698 16635246 details
Grin2bPpp3caBioGRID, IntAct, MINT10862698 16635246 details
Grin2bDlg3BioGRID, IntAct, MINT10862698 16635246 details
Grin2bCamk2bBioGRID, IntAct, MINT10862698 16635246 details
Grin2bTrp53bp1MINT10862698 details
Grin2bTjp1MINT10862698 details
Grin2bInaMINT10862698 details
Grin2bAppl1MINT10862698 details
Grin2bDlg1IntAct, MINT10862698 16635246 details
Grin2bMyo5aIntAct, MINT10862698 16635246 details
Grin2bTuba1aBioGRID, IntAct, MINT10862698 16635246 details
Grin2bBsnMINT10862698 details
Grin2bPfklMINT10862698 details
Grin2bDlgap1BioGRID, IntAct, MINT10862698 16635246 27507650 28671696 details
Grin2bDlg2BioGRID, IntAct, MINT10862698 16635246 details
Grin2bGrin2bIntAct, MINT10862698 16635246 20141836 details
Grin2bGrm1BioGRID, IntAct, MINT10862698 16635246 details
Grin2bFusMINT10862698 details
Grin2bYwhabIntAct16635246 details
Grin2bLca5IntAct16635246 details
Grin2bMyl6IntAct16635246 details
Grin2bMyh9IntAct16635246 details
Grin2bMyh10IntAct16635246 details
Grin2bMyl12bIntAct16635246 details
Grin2bSlc25a5IntAct16635246 details
Grin2bSlc25a4IntAct16635246 details
Grin2bSlc25a12IntAct16635246 details
Grin2bSlc25a22IntAct16635246 details
Grin2bSyt1IntAct16635246 details
Grin2bSyngr1IntAct16635246 details
Grin2bStxbp1IntAct16635246 details
Grin2bStx1aIntAct16635246 details
Grin2bRtn1IntAct16635246 details
Grin2bSnap25IntAct16635246 details
Grin2bFabp5IntAct16635246 details
Grin2bLin7aIntAct16635246 details
Grin2bLgi1IntAct16635246 details
Grin2bNeflIntAct16635246 details
Grin2bNefmIntAct16635246 details
Grin2bLmnb1IntAct16635246 details
Grin2bGsnIntAct16635246 details
Grin2bDbn1IntAct16635246 details
Grin2bCse1lIntAct16635246 details
Grin2bCapzbIntAct16635246 details
Grin2bCapza2IntAct16635246 details
Grin2bAdam22IntAct16635246 details
Grin2bMogIntAct16635246 details
Grin2bMbpIntAct16635246 details
Grin2bSptbn1IntAct16635246 details
Grin2bActn4IntAct16635246 details
Grin2bActn3IntAct16635246 details
Grin2bArpc4IntAct16635246 details
Grin2bArpc3IntAct16635246 details
Grin2bArpc2IntAct16635246 details
Grin2bActbIntAct16635246 details
Grin2bRpl7IntAct16635246 details
Grin2bRpl13aIntAct16635246 details
Grin2bRpl13IntAct16635246 details
Grin2bPhb2IntAct16635246 details
Grin2bPrdx2IntAct16635246 details
Grin2bTpi1IntAct16635246 details
Grin2bPrdx1IntAct16635246 details
Grin2bLdhbIntAct16635246 details
Grin2bLdhaIntAct16635246 details
Grin2bGot2IntAct16635246 details
Grin2bGlulIntAct16635246 details
Grin2bGapdhIntAct16635246 details
Grin2bEhmt2IntAct16635246 details
Grin2bDpysl2IntAct16635246 details
Grin2bPrdx6IntAct16635246 details
Grin2bAldocIntAct16635246 details
Grin2bAco2IntAct16635246 details
Grin2bStk39IntAct16635246 details
Grin2bVegfaIntAct16635246 details
Grin2bCalb2IntAct16635246 details
Grin2bArf3IntAct16635246 details
Grin2bNdufv2IntAct16635246 details
Grin2bAtp6v0d1IntAct16635246 details
Grin2bAtp6v1aIntAct16635246 details
Grin2bAtp5c1IntAct16635246 details
Grin2bAtp5a1IntAct16635246 details
Grin2bGap43IntAct16635246 details
Grin2bRanIntAct16635246 details
Grin2bRab6aIntAct16635246 details
Grin2bRab37IntAct16635246 details
Grin2bRab2aIntAct16635246 details
Grin2bGnb4IntAct16635246 details
Grin2bGnb2IntAct16635246 details
Grin2bGnb1IntAct16635246 details
Grin2bGnasIntAct16635246 details
Grin2bMap2k7IntAct16635246 details
Grin2bYwhazIntAct16635246 details
Grin2bYwhagIntAct16635246 details
Grin2bYwhahIntAct16635246 details
Grin2bYwhaeIntAct16635246 details
Grin2bMpp2IntAct16635246 details
Grin2bSlc1a2IntAct16635246 details
Grin2bVdac2IntAct16635246 details
Grin2bVdac1IntAct16635246 details
Grin2bAtp1a3IntAct16635246 details
Grin2bAtp1a1IntAct16635246 details
Grin2bIrs1IntAct16635246 details
Grin2bPik3caIntAct16635246 details
Grin2bPlcb1IntAct16635246 details
Grin2bArntIntAct16635246 details
Grin2bCalm2IntAct16635246 details
Grin2bCalm3IntAct16635246 details
Grin2bBadIntAct16635246 details
Grin2bKalrnBioGRID, IntAct16635246 28706196 details
Grin2bFgd4IntAct16635246 details
Grin2bRap2aIntAct16635246 details
Grin2bRab3aIntAct16635246 details
Grin2bRab27aIntAct16635246 details
Grin2bRab11aIntAct16635246 details
Grin2bPtpn1IntAct16635246 details
Grin2bPrkacbIntAct16635246 details
Grin2bPrkar1aIntAct16635246 details
Grin2bPrkar1bIntAct16635246 details
Grin2bPdpk1IntAct16635246 details
Grin2bMapk10IntAct16635246 details
Grin2bMap2k3IntAct16635246 details
Grin2bGsk3bIntAct16635246 details
Grin2bAkt2IntAct16635246 details
Grin2bMapk8ip1IntAct16635246 details
Grin2bMyo1bIntAct16635246 details
Grin2bRack1IntAct16635246 details
Grin2bFlncIntAct16635246 details
Grin2bNeto1DIP19243221 details
Grin2bTnikBioGRID, IntAct28671696 details
Grin2bShank3BioGRID, IntAct27507650 28671696 details
Grin2bAgap2BioGRID, IntAct28706196 details
Grin2bGrid1BioGRID32325033 details
Grin2bGrid2BioGRID32325033 details
Grin2bIl16BioGRID32325033 details
Grin2bTanc1BioGRID32325033 details