Entity Details

Primary name Grn
Entity type gene
Source Source Link

Details

PrimaryID14824
RefseqGene
SymbolGrn
Namegranulin
Chromosome11
Location11 66.29 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsGRN_MOUSE

GO terms

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GOName
GO:0001835 blastocyst hatching
GO:0002265 astrocyte activation involved in immune response
GO:0002282 microglial cell activation involved in immune response
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005739 mitochondrion
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005768 endosome
GO:0005770 late endosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0007040 lysosome organization
GO:0007041 lysosomal transport
GO:0007042 lysosomal lumen acidification
GO:0007566 embryo implantation
GO:0008284 positive regulation of cell population proliferation
GO:0010595 positive regulation of endothelial cell migration
GO:0010976 positive regulation of neuron projection development
GO:0016020 membrane
GO:0030335 positive regulation of cell migration
GO:0031982 vesicle
GO:0032355 response to estradiol
GO:0035641 locomotory exploration behavior
GO:0035988 chondrocyte proliferation
GO:0043524 negative regulation of neuron apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0045766 positive regulation of angiogenesis
GO:0045824 negative regulation of innate immune response
GO:0048488 synaptic vesicle endocytosis
GO:0048680 positive regulation of axon regeneration
GO:0050679 positive regulation of epithelial cell proliferation
GO:0050727 regulation of inflammatory response
GO:0050728 negative regulation of inflammatory response
GO:0050821 protein stabilization
GO:0051087 chaperone binding
GO:0051346 negative regulation of hydrolase activity
GO:0060041 retina development in camera-type eye
GO:0060179 male mating behavior
GO:0060266 negative regulation of respiratory burst involved in inflammatory response
GO:0060999 positive regulation of dendritic spine development
GO:0061351 neural precursor cell proliferation
GO:0098793 presynapse
GO:0106016 positive regulation of inflammatory response to wounding
GO:1900426 positive regulation of defense response to bacterium
GO:1902564 negative regulation of neutrophil activation
GO:1903334 positive regulation of protein folding
GO:1903979 negative regulation of microglial cell activation
GO:1905146 lysosomal protein catabolic process
GO:1905247 positive regulation of aspartic-type peptidase activity
GO:1905671 regulation of lysosome organization
GO:1905673 positive regulation of lysosome organization

Diseases

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Interactions

58 interactions

InteractorPartnerSourcesPublicationsLink
GrnPRKAA1BioGRID, IntAct20368287 details
GrnPsapBioGRID, UniProt26370502 details
GrnSlpiBioGRID12526812 details
GrnTnfrsf1bMINT24070898 details
GrnKcnq2IntAct19022416 details
GrnPSAPUniProt26370502 details
GrnEedBioGRID24457600 details
GrnPpp1r9bBioGRID30562941 details
GrnAtg16l1BioGRID30196744 details
GrnGCGBioGRID30713523 details
GrnGrnBioGRID26370502 details
GrnPdia4BioGRID26370502 details
GrnP4hbBioGRID26370502 details
GrnHspa5BioGRID26370502 details
GrnDnajc10BioGRID26370502 details
GrnPdia6BioGRID26370502 details
GrnG6pdxBioGRID26370502 details
GrnGsrBioGRID26370502 details
GrnCapza2BioGRID26370502 details
GrnActg1BioGRID26370502 details
GrnTubb4aBioGRID26370502 details
GrnActbl2BioGRID26370502 details
GrnGartBioGRID26370502 details
GrnTubb6BioGRID26370502 details
GrnCapzbBioGRID26370502 details
GrnPfn2BioGRID26370502 details
GrnDnpepBioGRID26370502 details
GrnTxn1BioGRID26370502 details
GrnPalldBioGRID26370502 details
GrnAnxa2BioGRID26370502 details
GrnFarsbBioGRID26370502 details
GrnEef1a1BioGRID26370502 details
GrnOpa1BioGRID26370502 details
GrnDpysl3BioGRID26370502 details
GrnEef1a2BioGRID26370502 details
GrnPmlBioGRID26370502 details
GrnFlnaBioGRID26370502 details
GrnCtpsBioGRID26370502 details
GrnPkmBioGRID26370502 details
GrnMcm3BioGRID26370502 details
GrnFasnBioGRID26370502 details
GrnCarsBioGRID26370502 details
GrnPcbp1BioGRID26370502 details
GrnCrklBioGRID26370502 details
GrnHspa8BioGRID26370502 details
GrnPrdx4BioGRID26370502 details
GrnKhsrpBioGRID26370502 details
GrnOas1bBioGRID26370502 details
GrnVimBioGRID26370502 details
GrnHspa9BioGRID26370502 details
GrnH4c4BioGRID26370502 details
GrnHspa2BioGRID26370502 details
GrnTuba1aBioGRID26370502 details
GrnPrdx1BioGRID26370502 details
GrnHspa1aBioGRID26370502 details
GrnPdia3BioGRID26370502 details
GrnCfdBioGRID30550785 details
GrnFndc5BioGRID30550785 details