Entity Details

Primary name RN126_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ91YL2
EntryNameRN126_MOUSE
FullNameE3 ubiquitin-protein ligase RNF126
TaxID10090
Evidenceevidence at protein level
Length313
SequenceStatuscomplete
DateCreated2005-09-27
DateModified2021-06-02

Ontological Relatives

GenesRnf126

GO terms

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GOName
GO:0005154 epidermal growth factor receptor binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006513 protein monoubiquitination
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042127 regulation of cell population proliferation
GO:0042147 retrograde transport, endosome to Golgi
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
GO:0070534 protein K63-linked ubiquitination
GO:0070936 protein K48-linked ubiquitination
GO:0071629 cytoplasm protein quality control by the ubiquitin-proteasome system

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR039525 E3 ubiquitin-protein ligase RNF126-like, zinc-ribbonDomainDomain
IPR039571 RNF126, RING finger, H2 subclassDomainDomain
IPR039572 E3 ubiquitin-protein ligase RNF126FamilyFamily

Diseases

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Interactions

4 interactions