Entity Details

Primary name Hic1
Entity type gene
Source Source Link

Details

PrimaryID15248
RefseqGene
SymbolHic1
Namehypermethylated in cancer 1
Chromosome11
Location11 45.76 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsHIC1_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007275 multicellular organism development
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016055 Wnt signaling pathway
GO:0030178 negative regulation of Wnt signaling pathway
GO:0042826 histone deacetylase binding
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
Hic1Tcf7l2BioGRID, MINT16724116 details
Hic1Sirt1UniProt16269335 details
Hic1SIRT1UniProt17283066 details