Entity Details

Primary name Hmgb1
Entity type gene
Source Source Link

Details

PrimaryID15289
RefseqGene
SymbolHmgb1
Namehigh mobility group box 1
Chromosome5
Location5 89.18 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-01-11
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsHMGB1_MOUSE

GO terms

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GOName
GO:0000400 four-way junction DNA binding
GO:0000401 open form four-way junction DNA binding
GO:0000402 crossed form four-way junction DNA binding
GO:0000405 bubble DNA binding
GO:0000793 condensed chromosome
GO:0000976 transcription cis-regulatory region binding
GO:0001530 lipopolysaccharide binding
GO:0001654 eye development
GO:0001773 myeloid dendritic cell activation
GO:0001786 phosphatidylserine binding
GO:0001934 positive regulation of protein phosphorylation
GO:0001935 endothelial cell proliferation
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0002218 activation of innate immune response
GO:0002270 plasmacytoid dendritic cell activation
GO:0002281 macrophage activation involved in immune response
GO:0002437 inflammatory response to antigenic stimulus
GO:0002643 regulation of tolerance induction
GO:0002840 regulation of T cell mediated immune response to tumor cell
GO:0003681 bent DNA binding
GO:0003684 damaged DNA binding
GO:0003690 double-stranded DNA binding
GO:0003713 transcription coactivator activity
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0005125 cytokine activity
GO:0005178 integrin binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0006284 base-excision repair
GO:0006342 chromatin silencing
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006914 autophagy
GO:0006954 inflammatory response
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008201 heparin binding
GO:0008301 DNA binding, bending
GO:0009986 cell surface
GO:0010508 positive regulation of autophagy
GO:0010858 calcium-dependent protein kinase regulator activity
GO:0016829 lyase activity
GO:0017053 transcription repressor complex
GO:0017055 negative regulation of RNA polymerase II transcription preinitiation complex assembly
GO:0019958 C-X-C chemokine binding
GO:0030295 protein kinase activator activity
GO:0030324 lung development
GO:0030335 positive regulation of cell migration
GO:0031497 chromatin assembly
GO:0032072 regulation of restriction endodeoxyribonuclease activity
GO:0032392 DNA geometric change
GO:0032425 positive regulation of mismatch repair
GO:0032689 negative regulation of interferon-gamma production
GO:0032727 positive regulation of interferon-alpha production
GO:0032728 positive regulation of interferon-beta production
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032733 positive regulation of interleukin-10 production
GO:0032735 positive regulation of interleukin-12 production
GO:0032755 positive regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0033151 V(D)J recombination
GO:0034137 positive regulation of toll-like receptor 2 signaling pathway
GO:0034145 positive regulation of toll-like receptor 4 signaling pathway
GO:0034165 positive regulation of toll-like receptor 9 signaling pathway
GO:0035711 T-helper 1 cell activation
GO:0035767 endothelial cell chemotaxis
GO:0035868 alphav-beta3 integrin-HMGB1 complex
GO:0042104 positive regulation of activated T cell proliferation
GO:0043005 neuron projection
GO:0043065 positive regulation of apoptotic process
GO:0043277 apoptotic cell clearance
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation
GO:0043388 positive regulation of DNA binding
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0043537 negative regulation of blood vessel endothelial cell migration
GO:0045063 T-helper 1 cell differentiation
GO:0045087 innate immune response
GO:0045089 positive regulation of innate immune response
GO:0045639 positive regulation of myeloid cell differentiation
GO:0045819 positive regulation of glycogen catabolic process
GO:0045931 positive regulation of mitotic cell cycle
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046330 positive regulation of JNK cascade
GO:0050930 induction of positive chemotaxis
GO:0051106 positive regulation of DNA ligation
GO:0051384 response to glucocorticoid
GO:0070182 DNA polymerase binding
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071222 cellular response to lipopolysaccharide
GO:0071639 positive regulation of monocyte chemotactic protein-1 production
GO:0090026 positive regulation of monocyte chemotaxis
GO:0090303 positive regulation of wound healing
GO:0097100 supercoiled DNA binding
GO:0097350 neutrophil clearance
GO:0098761 cellular response to interleukin-7
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1903672 positive regulation of sprouting angiogenesis
GO:1905564 positive regulation of vascular endothelial cell proliferation
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production
GO:2000426 negative regulation of apoptotic cell clearance
GO:2000819 regulation of nucleotide-excision repair
GO:2001200 positive regulation of dendritic cell differentiation

Diseases

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