Entity Details

Primary name Hsf1
Entity type gene
Source Source Link

Details

PrimaryID15499
RefseqGene
SymbolHsf1
Nameheat shock factor 1
Chromosome15
Location15 35.95 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsHSF1_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000165 MAPK cascade
GO:0000776 kinetochore
GO:0000791 euchromatin
GO:0000792 heterochromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001701 in utero embryonic development
GO:0001892 embryonic placenta development
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006397 mRNA processing
GO:0006468 protein phosphorylation
GO:0006952 defense response
GO:0007143 female meiotic nuclear division
GO:0007283 spermatogenesis
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0009299 mRNA transcription
GO:0009408 response to heat
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010667 negative regulation of cardiac muscle cell apoptotic process
GO:0016605 PML body
GO:0019901 protein kinase binding
GO:0031072 heat shock protein binding
GO:0031333 negative regulation of protein-containing complex assembly
GO:0031490 chromatin DNA binding
GO:0032355 response to estradiol
GO:0032496 response to lipopolysaccharide
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032991 protein-containing complex
GO:0033574 response to testosterone
GO:0034605 cellular response to heat
GO:0034620 cellular response to unfolded protein
GO:0034622 cellular protein-containing complex assembly
GO:0040018 positive regulation of multicellular organism growth
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042802 identical protein binding
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0043621 protein self-association
GO:0045120 pronucleus
GO:0045931 positive regulation of mitotic cell cycle
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0048471 perinuclear region of cytoplasm
GO:0051028 mRNA transport
GO:0051879 Hsp90 protein binding
GO:0060136 embryonic process involved in female pregnancy
GO:0061408 positive regulation of transcription from RNA polymerase II promoter in response to heat stress
GO:0061770 translation elongation factor binding
GO:0070301 cellular response to hydrogen peroxide
GO:0071230 cellular response to amino acid stimulus
GO:0071276 cellular response to cadmium ion
GO:0071280 cellular response to copper ion
GO:0071392 cellular response to estradiol stimulus
GO:0071407 cellular response to organic cyclic compound
GO:0071478 cellular response to radiation
GO:0071480 cellular response to gamma radiation
GO:0072738 cellular response to diamide
GO:0090084 negative regulation of inclusion body assembly
GO:0090261 positive regulation of inclusion body assembly
GO:0097165 nuclear stress granule
GO:0097431 mitotic spindle pole
GO:0097677 STAT family protein binding
GO:0098847 sequence-specific single stranded DNA binding
GO:0101031 chaperone complex
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1900034 regulation of cellular response to heat
GO:1900365 positive regulation of mRNA polyadenylation
GO:1901215 negative regulation of neuron death
GO:1902512 positive regulation of apoptotic DNA fragmentation
GO:1903936 cellular response to sodium arsenite
GO:1904385 cellular response to angiotensin
GO:1904528 positive regulation of microtubule binding
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding
GO:1990904 ribonucleoprotein complex
GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining

Diseases

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Interactions

16 interactions

InteractorPartnerSourcesPublicationsLink
Hsf1STUB1MINT16293251 details
Hsf1HSPA8MINT16293251 details
Hsf1Atf3BioGRID17766920 details
Hsf1RelaBioGRID17766920 details
Hsf1Hsp90ab1BioGRID17785525 22367781 details
Hsf1YIPF5BioGRID, IntAct26496610 details
Hsf1OFD1BioGRID, IntAct26496610 details
Hsf1FZD1BioGRID, IntAct26496610 details
Hsf1JPH1BioGRID, IntAct26496610 details
Hsf1RB1CC1BioGRID, IntAct26496610 details
Hsf1DGCR8BioGRID, IntAct26496610 details
Hsf1RAD51DBioGRID, IntAct26496610 details
Hsf1FLYWCH1BioGRID, IntAct26496610 details
Hsf1SNW1BioGRID, IntAct26496610 details
Hsf1NDUFV2BioGRID, IntAct26496610 details
Hsf1BAIAP2L1BioGRID, IntAct26496610 details