Entity Details

Primary name Hsp90ab1
Entity type gene
Source Source Link

Details

PrimaryID15516
RefseqGene
SymbolHsp90ab1
Nameheat shock protein 90 alpha (cytosolic), class B member 1
Chromosome17
Location17 22.59 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsHS90B_MOUSE

GO terms

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GOName
GO:0001890 placenta development
GO:0002134 UTP binding
GO:0002135 CTP binding
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006457 protein folding
GO:0007004 telomere maintenance via telomerase
GO:0008180 COP9 signalosome
GO:0009651 response to salt stress
GO:0009986 cell surface
GO:0010033 response to organic substance
GO:0016234 inclusion body
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016887 ATP hydrolysis activity
GO:0017098 sulfonylurea receptor binding
GO:0019062 virion attachment to host cell
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0021955 central nervous system neuron axonogenesis
GO:0030010 establishment of cell polarity
GO:0030235 nitric-oxide synthase regulator activity
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030911 TPR domain binding
GO:0031072 heat shock protein binding
GO:0031396 regulation of protein ubiquitination
GO:0031526 brush border membrane
GO:0031625 ubiquitin protein ligase binding
GO:0032092 positive regulation of protein binding
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032516 positive regulation of phosphoprotein phosphatase activity
GO:0032564 dATP binding
GO:0032991 protein-containing complex
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0034605 cellular response to heat
GO:0034751 aryl hydrocarbon receptor complex
GO:0042220 response to cocaine
GO:0042277 peptide binding
GO:0042307 positive regulation of protein import into nucleus
GO:0042470 melanosome
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042826 histone deacetylase binding
GO:0043008 ATP-dependent protein binding
GO:0043025 neuronal cell body
GO:0043066 negative regulation of apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0044183 protein folding chaperone
GO:0044294 dendritic growth cone
GO:0044295 axonal growth cone
GO:0044325 transmembrane transporter binding
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045597 positive regulation of cell differentiation
GO:0045793 positive regulation of cell size
GO:0046983 protein dimerization activity
GO:0048156 tau protein binding
GO:0048471 perinuclear region of cytoplasm
GO:0048675 axon extension
GO:0050821 protein stabilization
GO:0051082 unfolded protein binding
GO:0051131 chaperone-mediated protein complex assembly
GO:0051248 negative regulation of protein metabolic process
GO:0051897 positive regulation of protein kinase B signaling
GO:0051973 positive regulation of telomerase activity
GO:0060334 regulation of interferon-gamma-mediated signaling pathway
GO:0060338 regulation of type I interferon-mediated signaling pathway
GO:0070182 DNA polymerase binding
GO:0071353 cellular response to interleukin-4
GO:0071407 cellular response to organic cyclic compound
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:0097435 supramolecular fiber organization
GO:0097718 disordered domain specific binding
GO:0120293 dynein axonemal particle
GO:1901389 negative regulation of transforming growth factor beta activation
GO:1901799 negative regulation of proteasomal protein catabolic process
GO:1903660 negative regulation of complement-dependent cytotoxicity
GO:1903827 regulation of cellular protein localization
GO:1904031 positive regulation of cyclin-dependent protein kinase activity
GO:1905323 telomerase holoenzyme complex assembly
GO:1990226 histone methyltransferase binding
GO:1990565 HSP90-CDC37 chaperone complex
GO:1990913 sperm head plasma membrane
GO:1990917 ooplasm
GO:2000010 positive regulation of protein localization to cell surface

Diseases

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Interactions

126 interactions

InteractorPartnerSourcesPublicationsLink
Hsp90ab1Chordc1BioGRID, MINT15642353 16083881 32325033 details
Hsp90ab1Hspa1bBioGRID8157642 details
Hsp90ab1Cdkn2aBioGRID16582619 details
Hsp90ab1PgrBioGRID9178755 details
Hsp90ab1Itgb1bp2BioGRID18474241 details
Hsp90ab1CCNB2MINT17408621 details
Hsp90ab1NelfeIntAct22579285 details
Hsp90ab1Hdac6BioGRID15916966 17785525 22367781 details
Hsp90ab1Traf6BioGRID16196101 details
Hsp90ab1Nod1BioGRID16083881 details
Hsp90ab1GcgrBioGRID22457490 details
Hsp90ab1Ip6k2BioGRID18195352 details
Hsp90ab1Irf3BioGRID16394098 details
Hsp90ab1Nr1i3BioGRID12885400 details
Hsp90ab1Ptges3BioGRID22123826 32325033 details
Hsp90ab1Stub1BioGRID23612611 details
Hsp90ab1Hsf1BioGRID17785525 22367781 details
Hsp90ab1VcpBioGRID17785525 details
Hsp90ab1Mapk7BioGRID23428871 details
Hsp90ab1Hsp90ab1BioGRID22367781 details
Hsp90ab1Akt1BioGRID10995457 details
Hsp90ab1DNAJB2BioGRID22396390 details
Hsp90ab1Mt3BioGRID15802640 17018872 details
Hsp90ab1AhrBioGRID8396713 details
Hsp90ab1Wdfy4BioGRID30409884 details
Hsp90ab1CkbBioGRID15802640 details
Hsp90ab1YwhabBioGRID, IntAct16635246 32325033 details
Hsp90ab1Irs1IntAct15602769 details
Hsp90ab1CALM1BioGRID, IntAct16512683 details
Hsp90ab1CALM2IntAct16512683 details
Hsp90ab1CALM3IntAct16512683 details
Hsp90ab1YwhazIntAct19562802 details
Hsp90ab1Dlg4IntAct19455133 details
Hsp90ab1EedBioGRID, IntAct20064375 24457600 details
Hsp90ab1Sult2b1MINT20718863 details
Hsp90ab1SNCAIntAct20340160 details
Hsp90ab1YwhahMINT21311561 details
Hsp90ab1Nphp4BioGRID, IntAct21565611 details
Hsp90ab1Nphp1BioGRID, IntAct21565611 details
Hsp90ab1Iqcb1BioGRID, IntAct21565611 details
Hsp90ab1Neurl1aIntAct22153079 details
Hsp90ab1Cdk9IntAct20593818 details
Hsp90ab1LRRK2IntAct18367605 24687852 details
Hsp90ab1Rab33bIntAct26885862 details
Hsp90ab1Rab19IntAct26885862 details
Hsp90ab1Rab1aIntAct26885862 details
Hsp90ab1Rab3aIntAct26885862 details
Hsp90ab1WRAP73UniProt26675238 details
Hsp90ab1Tsc1BioGRID, IntAct28671696 details
Hsp90ab1Kcnq1IntAct24952909 details
Hsp90ab1Cav3IntAct24952909 details
Hsp90ab1LRSAM1IntAct27615052 details
Hsp90ab1YwhaeBioGRID16944949 32325033 details
Hsp90ab1Mks1BioGRID21565611 details
Hsp90ab1CFTRBioGRID17110338 details
Hsp90ab1HACE1BioGRID24614889 details
Hsp90ab1Fancd2BioGRID28378742 details
Hsp90ab1PTENBioGRID18307411 details
Hsp90ab1Cibar1BioGRID29459677 details
Hsp90ab1Ttc23BioGRID29459677 details
Hsp90ab1Tedc2BioGRID29459677 details
Hsp90ab1Ppp1r9bBioGRID30562941 details
Hsp90ab1Atg16l1BioGRID30196744 details
Hsp90ab1GCGBioGRID30713523 details
Hsp90ab1Tfe3BioGRID30595499 details
Hsp90ab1YWHAZBioGRID29530978 details
Hsp90ab1Cops2BioGRID32325033 details
Hsp90ab1Dclk2BioGRID32325033 details
Hsp90ab1Dnajb1BioGRID32325033 details
Hsp90ab1Dynll1BioGRID32325033 details
Hsp90ab1Eif3hBioGRID32325033 details
Hsp90ab1Fam162aBioGRID32325033 details
Hsp90ab1Cops5BioGRID32325033 details
Hsp90ab1Cops6BioGRID32325033 details
Hsp90ab1Pgk1BioGRID32325033 details
Hsp90ab1Iars2BioGRID32325033 details
Hsp90ab1Mthfd1BioGRID32325033 details
Hsp90ab1Ppp6r3BioGRID32325033 details
Hsp90ab1Rpap3BioGRID32325033 details
Hsp90ab1Rpl30BioGRID32325033 details
Hsp90ab1RpsaBioGRID32325033 details
Hsp90ab1Slc2a1BioGRID32325033 details
Hsp90ab1Stk32cBioGRID32325033 details
Hsp90ab1Tomm34BioGRID32325033 details
Hsp90ab1ActbBioGRID32325033 details
Hsp90ab1Actn4BioGRID32325033 details
Hsp90ab1Ahsa1BioGRID32325033 details
Hsp90ab1Atp5a1BioGRID32325033 details
Hsp90ab1Ccar2BioGRID32325033 details
Hsp90ab1Cdc37BioGRID32325033 details
Hsp90ab1Cops7aBioGRID32325033 details
Hsp90ab1Cops8BioGRID32325033 details
Hsp90ab1Fbxo3BioGRID32325033 details
Hsp90ab1AipBioGRID32325033 details
Hsp90ab1Cops3BioGRID32325033 details
Hsp90ab1Cops4BioGRID32325033 details
Hsp90ab1Epb41l2BioGRID32325033 details
Hsp90ab1Hsp90aa1BioGRID32325033 details
Hsp90ab1Pfdn2BioGRID32325033 details
Hsp90ab1Hspa2BioGRID32325033 details
Hsp90ab1Hspa5BioGRID32325033 details
Hsp90ab1Hspa8BioGRID32325033 details
Hsp90ab1Hspe1BioGRID32325033 details
Hsp90ab1Hsph1BioGRID32325033 details
Hsp90ab1Myh9BioGRID32325033 details
Hsp90ab1Nudcd2BioGRID32325033 details
Hsp90ab1Plcg1BioGRID32325033 details
Hsp90ab1PpidBioGRID32325033 details
Hsp90ab1Ppp5cBioGRID32325033 details
Hsp90ab1Psat1BioGRID32325033 details
Hsp90ab1Rpl4BioGRID32325033 details
Hsp90ab1Rpl6BioGRID32325033 details
Hsp90ab1Rpl8BioGRID32325033 details
Hsp90ab1Rps11BioGRID32325033 details
Hsp90ab1Rps13BioGRID32325033 details
Hsp90ab1Sars2BioGRID32325033 details
Hsp90ab1SgtaBioGRID32325033 details
Hsp90ab1Stip1BioGRID32325033 details
Hsp90ab1Sugt1BioGRID32325033 details
Hsp90ab1YwhaqBioGRID32325033 details
Hsp90ab1Fkbp5BioGRID32325033 details
Hsp90ab1CfdBioGRID30550785 details
Hsp90ab1Fndc5BioGRID30550785 details
Hsp90ab1Mettl21eBioGRID31162944 details
Hsp90ab1Fzr1BioGRID32434143 details
Hsp90ab1UnkBioGRID25737280 details