Entity Details

Primary name TWF1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ91YR1
EntryNameTWF1_MOUSE
FullNameTwinfilin-1
TaxID10090
Evidenceevidence at protein level
Length350
SequenceStatuscomplete
DateCreated2004-02-02
DateModified2021-06-02

Ontological Relatives

GenesTwf1

GO terms

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GOName
GO:0003779 actin binding
GO:0003785 actin monomer binding
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005911 cell-cell junction
GO:0010591 regulation of lamellipodium assembly
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0010976 positive regulation of neuron projection development
GO:0015629 actin cytoskeleton
GO:0030016 myofibril
GO:0030042 actin filament depolymerization
GO:0030175 filopodium
GO:0030837 negative regulation of actin filament polymerization
GO:0042989 sequestering of actin monomers
GO:0043538 regulation of actin phosphorylation
GO:0044877 protein-containing complex binding
GO:0048471 perinuclear region of cytoplasm
GO:0051015 actin filament binding
GO:0051016 barbed-end actin filament capping

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002108 Actin-depolymerising factor homology domainDomainDomain
IPR028458 TwinfilinFamilyFamily
IPR029006 ADF-H/Gelsolin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TWF1_MOUSEITA2B_MOUSEBioGRID30333137 details