Entity Details

Primary name Irf8
Entity type gene
Source Source Link

Details

PrimaryID15900
RefseqGene
SymbolIrf8
Nameinterferon regulatory factor 8
Chromosome8
Location8 70.05 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsIRF8_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0002273 plasmacytoid dendritic cell differentiation
GO:0002314 germinal center B cell differentiation
GO:0002316 follicular B cell differentiation
GO:0002376 immune system process
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006909 phagocytosis
GO:0006914 autophagy
GO:0006955 immune response
GO:0009617 response to bacterium
GO:0030099 myeloid cell differentiation
GO:0032479 regulation of type I interferon production
GO:0032729 positive regulation of interferon-gamma production
GO:0032735 positive regulation of interleukin-12 production
GO:0042742 defense response to bacterium
GO:0042832 defense response to protozoan
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0071222 cellular response to lipopolysaccharide
GO:0071346 cellular response to interferon-gamma
GO:0097028 dendritic cell differentiation
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

7 interactions