Entity Details

Primary name Ikbkb
Entity type gene
Source Source Link

Details

PrimaryID16150
RefseqGene
SymbolIkbkb
Nameinhibitor of kappaB kinase beta
Chromosome8
Location8
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-23
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsIKKB_MOUSE

GO terms

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GOName
GO:0001782 B cell homeostasis
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006468 protein phosphorylation
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0007252 I-kappaB phosphorylation
GO:0008284 positive regulation of cell population proliferation
GO:0008384 IkappaB kinase activity
GO:0008385 IkappaB kinase complex
GO:0009898 cytoplasmic side of plasma membrane
GO:0010765 positive regulation of sodium ion transport
GO:0010976 positive regulation of neuron projection development
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0030866 cortical actin cytoskeleton organization
GO:0031175 neuron projection development
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035509 negative regulation of myosin-light-chain-phosphatase activity
GO:0035631 CD40 receptor complex
GO:0042325 regulation of phosphorylation
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043231 intracellular membrane-bounded organelle
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0061847 response to cholecystokinin
GO:0070498 interleukin-1-mediated signaling pathway
GO:0071356 cellular response to tumor necrosis factor
GO:0072659 protein localization to plasma membrane
GO:0097110 scaffold protein binding
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901216 positive regulation of neuron death
GO:1903140 regulation of establishment of endothelial barrier
GO:1903347 negative regulation of bicellular tight junction assembly
GO:1990459 transferrin receptor binding
GO:2001259 positive regulation of cation channel activity

Diseases

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Interactions

46 interactions

InteractorPartnerSourcesPublicationsLink
IkbkbSnx1IntAct15102471 details
IkbkbBzw2IntAct15102471 details
IkbkbRack1IntAct15102471 details
IkbkbPpp2r1aIntAct15102471 details
IkbkbSdc3IntAct15102471 details
IkbkbGsta3IntAct15102471 details
IkbkbGmppbIntAct15102471 details
IkbkbKeap1IntAct15102471 details
IkbkbNagkIntAct15102471 details
IkbkbCtnna1IntAct15102471 details
IkbkbNme2IntAct15102471 details
IkbkbGtf2e2IntAct15102471 details
IkbkbUtp3IntAct15102471 details
IkbkbNFKBIAIntAct16291755 details
IkbkbIkbkgBioGRID, DIP, IntAct, MINT, UniProt10748240 12808104 16306937 16378096 18216269 18266467 20211142 20404153 21606193 23825957 23871670 24240172 24270572 details
IkbkbKEAP1IntAct20600852 details
IkbkbNkx3-2BioGRID21606193 details
IkbkbNfkbiaBioGRID21765415 21862579 22037600 details
IkbkbNfkbibBioGRID10593965 16260493 details
IkbkbOptnBioGRID21862579 details
IkbkbKlhl21BioGRID27387502 details
IkbkbUbcBioGRID28190767 details
IkbkbIkbkbIntAct16319058 details
IkbkbIrf7IntAct16612387 details
IkbkbSnap23BioGRID, IntAct18692471 23960234 details
IkbkbTNFDIP26649818 details
IkbkbBtrcBioGRID21606193 details
IkbkbRnf31BioGRID19136968 32325033 details
IkbkbRbck1BioGRID19136968 details
IkbkbCd40BioGRID18635759 details
IkbkbTnfrsf1aBioGRID16547522 29891719 32325033 details
IkbkbReg1BioGRID22037600 details
IkbkbSash1BioGRID23776175 details
IkbkbIKBKGBioGRID24266532 details
IkbkbRhoaBioGRID24240172 details
IkbkbSmn1BioGRID28214532 details
IkbkbTnfBioGRID29203883 details
IkbkbNlrc5IntAct20434986 details
IkbkbTnfrsf4DIP21282629 details
IkbkbTGFBR1BioGRID15761153 details
IkbkbACVR1BioGRID15761153 details
IkbkbFancd2BioGRID28378742 details
IkbkbFbxw11BioGRID32325033 details
IkbkbHivep2BioGRID32325033 details
IkbkbRelaBioGRID32325033 details
IkbkbTnfaip3BioGRID32325033 details