Entity Details

Primary name Il12a
Entity type gene
Source Source Link

Details

PrimaryID16159
RefseqGene
SymbolIl12a
Nameinterleukin 12a
Chromosome3
Location3 31.92 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsIL12A_MOUSE

GO terms

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GOName
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0005125 cytokine activity
GO:0005143 interleukin-12 receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005788 endoplasmic reticulum lumen
GO:0005796 Golgi lumen
GO:0006955 immune response
GO:0008083 growth factor activity
GO:0008283 cell population proliferation
GO:0009986 cell surface
GO:0010224 response to UV-B
GO:0016477 cell migration
GO:0031904 endosome lumen
GO:0032496 response to lipopolysaccharide
GO:0032700 negative regulation of interleukin-17 production
GO:0032729 positive regulation of interferon-gamma production
GO:0032816 positive regulation of natural killer cell activation
GO:0032946 positive regulation of mononuclear cell proliferation
GO:0034393 positive regulation of smooth muscle cell apoptotic process
GO:0035711 T-helper 1 cell activation
GO:0042102 positive regulation of T cell proliferation
GO:0042163 interleukin-12 beta subunit binding
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042832 defense response to protozoan
GO:0043514 interleukin-12 complex
GO:0045513 interleukin-27 binding
GO:0045582 positive regulation of T cell differentiation
GO:0045785 positive regulation of cell adhesion
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0046982 protein heterodimerization activity
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0050671 positive regulation of lymphocyte proliferation
GO:0050709 negative regulation of protein secretion
GO:0051135 positive regulation of NK T cell activation
GO:0071222 cellular response to lipopolysaccharide
GO:0097191 extrinsic apoptotic signaling pathway
GO:0098586 cellular response to virus
GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway
GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:2000510 positive regulation of dendritic cell chemotaxis

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
Il12aEbi3DIP, InnateDB18033300 20953201 details