Entity Details

Primary name Ilk
Entity type gene
Source Source Link

Details

PrimaryID16202
RefseqGene
SymbolIlk
Nameintegrin linked kinase
Chromosome7
Location7
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsILK_MOUSE

GO terms

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GOName
GO:0000902 cell morphogenesis
GO:0001558 regulation of cell growth
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001725 stress fiber
GO:0001934 positive regulation of protein phosphorylation
GO:0001954 positive regulation of cell-matrix adhesion
GO:0003151 outflow tract morphogenesis
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005178 integrin binding
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005925 focal adhesion
GO:0006468 protein phosphorylation
GO:0006469 negative regulation of protein kinase activity
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0007569 cell aging
GO:0008284 positive regulation of cell population proliferation
GO:0009967 positive regulation of signal transduction
GO:0010667 negative regulation of cardiac muscle cell apoptotic process
GO:0010761 fibroblast migration
GO:0014044 Schwann cell development
GO:0014912 negative regulation of smooth muscle cell migration
GO:0017124 SH3 domain binding
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0021675 nerve development
GO:0022011 myelination in peripheral nervous system
GO:0030017 sarcomere
GO:0030027 lamellipodium
GO:0030030 cell projection organization
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0030513 positive regulation of BMP signaling pathway
GO:0032288 myelin assembly
GO:0032956 regulation of actin cytoskeleton organization
GO:0032991 protein-containing complex
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0034446 substrate adhesion-dependent cell spreading
GO:0042327 positive regulation of phosphorylation
GO:0043025 neuronal cell body
GO:0043034 costamere
GO:0043066 negative regulation of apoptotic process
GO:0043195 terminal bouton
GO:0043198 dendritic shaft
GO:0043406 positive regulation of MAP kinase activity
GO:0043410 positive regulation of MAPK cascade
GO:0043491 protein kinase B signaling
GO:0043524 negative regulation of neuron apoptotic process
GO:0044877 protein-containing complex binding
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
GO:0045663 positive regulation of myoblast differentiation
GO:0045669 positive regulation of osteoblast differentiation
GO:0045773 positive regulation of axon extension
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0048812 neuron projection morphogenesis
GO:0050772 positive regulation of axonogenesis
GO:0050775 positive regulation of dendrite morphogenesis
GO:0051897 positive regulation of protein kinase B signaling
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0097435 supramolecular fiber organization
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:2000178 negative regulation of neural precursor cell proliferation

Diseases

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Interactions

56 interactions

InteractorPartnerSourcesPublicationsLink
IlkLIMS1IntAct, mbinfo10574708 11331308 12432066 details
IlkStub1BioGRID, MINT23612611 28546219 details
IlkMbpBioGRID18450752 details
IlkPARVBMINT18325335 details
IlkParvaBioGRID, DIP, IntAct, mbinfo, MINT11331308 12432066 19798050 19829382 23612611 28546219 details
IlkParvbBioGRID, DIP, MINT19798050 19829382 20164304 23612611 32325033 details
IlkLims1BioGRID, DIP, MINT12432066 19829382 20164304 23612611 28546219 details
IlkPARVAIntAct11331308 details
IlkTmsb4xBioGRID15565145 details
IlkNos3BioGRID28546219 details
IlkPxnBioGRID28546219 details
IlkAkt1BioGRID20164304 details
IlkYwhahMINT21311561 details
IlkSlc25a4MINT23612611 details
IlkDenn2bMINT23612611 details
IlkCcdc25MINT23612611 details
IlkPsmc3MINT23612611 details
IlkCct4MINT23612611 details
IlkCand1MINT23612611 details
IlkErlin2MINT23612611 details
IlkCopaMINT23612611 details
IlkHsph1MINT23612611 details
IlkLrp1MINT23612611 details
IlkEef1a1MINT23612611 details
IlkCct7MINT23612611 details
IlkBag2MINT23612611 details
IlkHspa8MINT23612611 details
IlkTubb5MINT23612611 details
IlkHsp90aa1MINT23612611 details
IlkCct8MINT23612611 details
IlkCct2MINT23612611 details
IlkMyh10MINT23612611 details
IlkRpl11MINT23612611 details
IlkSlc25a5MINT23612611 details
IlkSdhaMINT23612611 details
IlkSim1MINT23612611 details
IlkHspd1MINT23612611 details
IlkSpin1MINT23612611 details
IlkWdr1MINT23612611 details
IlkDnaja1MINT23612611 details
IlkNup188MINT23612611 details
IlkRps3MINT23612611 details
IlkDnaja2MINT23612611 details
IlkIlkMINT23612611 details
IlkRab5bIntAct26885862 details
IlkRab38IntAct26885862 details
IlkRab32IntAct26885862 details
IlkTbx5bhf-ucl26859351 details
IlkPou5f1BioGRID22083510 details
IlkFancd2BioGRID28378742 details
IlkAtxn1BioGRID30457570 details
IlkFanciBioGRID32325033 details
IlkHaus5BioGRID32325033 details
IlkLpcat1BioGRID32325033 details
IlkSdf4BioGRID32325033 details
IlkTecrBioGRID32325033 details