Entity Details

Primary name Itgb1
Entity type gene
Source Source Link

Details

PrimaryID16412
RefseqGene
SymbolItgb1
Nameintegrin beta 1 (fibronectin receptor beta)
Chromosome8
Location8
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsITB1_MOUSE

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000132 establishment of mitotic spindle orientation
GO:0001669 acrosomal vesicle
GO:0001701 in utero embryonic development
GO:0001708 cell fate specification
GO:0001894 tissue homeostasis
GO:0001968 fibronectin binding
GO:0002020 protease binding
GO:0002042 cell migration involved in sprouting angiogenesis
GO:0003779 actin binding
GO:0005102 signaling receptor binding
GO:0005178 integrin binding
GO:0005518 collagen binding
GO:0005604 basement membrane
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005925 focal adhesion
GO:0006909 phagocytosis
GO:0007155 cell adhesion
GO:0007159 leukocyte cell-cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007161 calcium-independent cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0008277 regulation of G protein-coupled receptor signaling pathway
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0008305 integrin complex
GO:0008354 germ cell migration
GO:0008542 visual learning
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010710 regulation of collagen catabolic process
GO:0010763 positive regulation of fibroblast migration
GO:0010811 positive regulation of cell-substrate adhesion
GO:0010976 positive regulation of neuron projection development
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0016477 cell migration
GO:0019900 kinase binding
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0021943 formation of radial glial scaffolds
GO:0023035 CD40 signaling pathway
GO:0030027 lamellipodium
GO:0030030 cell projection organization
GO:0030032 lamellipodium assembly
GO:0030056 hemidesmosome
GO:0030175 filopodium
GO:0030335 positive regulation of cell migration
GO:0031175 neuron projection development
GO:0031345 negative regulation of cell projection organization
GO:0031589 cell-substrate adhesion
GO:0031594 neuromuscular junction
GO:0031623 receptor internalization
GO:0032587 ruffle membrane
GO:0032594 protein transport within lipid bilayer
GO:0033627 cell adhesion mediated by integrin
GO:0034113 heterotypic cell-cell adhesion
GO:0034665 integrin alpha1-beta1 complex
GO:0034666 integrin alpha2-beta1 complex
GO:0034667 integrin alpha3-beta1 complex
GO:0034674 integrin alpha5-beta1 complex
GO:0034677 integrin alpha7-beta1 complex
GO:0034679 integrin alpha9-beta1 complex
GO:0034680 integrin alpha10-beta1 complex
GO:0034681 integrin alpha11-beta1 complex
GO:0035024 negative regulation of Rho protein signal transduction
GO:0035748 myelin sheath abaxonal region
GO:0038023 signaling receptor activity
GO:0042383 sarcolemma
GO:0042470 melanosome
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043197 dendritic spine
GO:0043235 receptor complex
GO:0043236 laminin binding
GO:0043547 positive regulation of GTPase activity
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0045214 sarcomere organization
GO:0045596 negative regulation of cell differentiation
GO:0045665 negative regulation of neuron differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045807 positive regulation of endocytosis
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0048675 axon extension
GO:0048738 cardiac muscle tissue development
GO:0048813 dendrite morphogenesis
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050804 modulation of chemical synaptic transmission
GO:0050839 cell adhesion molecule binding
GO:0050901 leukocyte tethering or rolling
GO:0051393 alpha-actinin binding
GO:0051726 regulation of cell cycle
GO:0051897 positive regulation of protein kinase B signaling
GO:0051951 positive regulation of glutamate uptake involved in transmission of nerve impulse
GO:0055007 cardiac muscle cell differentiation
GO:0055037 recycling endosome
GO:0070830 bicellular tight junction assembly
GO:0071404 cellular response to low-density lipoprotein particle stimulus
GO:0071711 basement membrane organization
GO:0090303 positive regulation of wound healing
GO:0097060 synaptic membrane
GO:0097386 glial cell projection
GO:0098639 collagen binding involved in cell-matrix adhesion
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099699 integral component of synaptic membrane
GO:0150003 regulation of spontaneous synaptic transmission
GO:0150103 reactive gliosis
GO:1901979 regulation of inward rectifier potassium channel activity
GO:1903078 positive regulation of protein localization to plasma membrane
GO:1990782 protein tyrosine kinase binding
GO:2000273 positive regulation of signaling receptor activity
GO:2000811 negative regulation of anoikis

Diseases

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Interactions

134 interactions

InteractorPartnerSourcesPublicationsLink
Itgb1VegfbBioGRID, IntAct15102471 32325033 details
Itgb1Nme2IntAct15102471 details
Itgb1LtbIntAct15102471 details
Itgb1Cnot1IntAct15102471 details
Itgb1Hgh1IntAct15102471 details
Itgb1Tln1BioGRID, IntAct21947080 30333137 details
Itgb1Fermt2BioGRID21947080 25808491 30333137 details
Itgb1Traf6BioGRID25808491 details
Itgb1GanabBioGRID30333137 details
Itgb1Plcg1BioGRID30333137 details
Itgb1Huwe1BioGRID30333137 details
Itgb1Ckap5BioGRID30333137 details
Itgb1Usp8BioGRID30333137 details
Itgb1Xpo1BioGRID30333137 details
Itgb1Ubr4BioGRID30333137 details
Itgb1FlnaBioGRID30333137 details
Itgb1Pdcd6ipBioGRID30333137 details
Itgb1Mov10BioGRID30333137 details
Itgb1PecrBioGRID30333137 details
Itgb1Gcn1BioGRID30333137 details
Itgb1Eif3bBioGRID30333137 details
Itgb1PlecBioGRID30333137 details
Itgb1Man2c1BioGRID30333137 details
Itgb1Smc2BioGRID30333137 details
Itgb1Iqgap1BioGRID30333137 details
Itgb1Dhx36BioGRID30333137 details
Itgb1Supt16BioGRID30333137 details
Itgb1Usp4BioGRID30333137 details
Itgb1Eif4g2BioGRID30333137 details
Itgb1JunBioGRID30333137 details
Itgb1Man2b1BioGRID30333137 details
Itgb1Supt5BioGRID30333137 details
Itgb1NclBioGRID30333137 details
Itgb1FasnBioGRID30333137 details
Itgb1CblBioGRID30333137 details
Itgb1Gdi1BioGRID30333137 details
Itgb1Usp5BioGRID30333137 details
Itgb1Actn4BioGRID30333137 details
Itgb1Kpnb1BioGRID30333137 details
Itgb1PrkdcBioGRID30333137 details
Itgb1XdhBioGRID30333137 details
Itgb1Psmd1BioGRID30333137 details
Itgb1Ddb1BioGRID30333137 details
Itgb1Myh10BioGRID30333137 details
Itgb1Dip2bBioGRID30333137 details
Itgb1Mthfd1lBioGRID30333137 details
Itgb1PfasBioGRID30333137 details
Itgb1OgdhBioGRID30333137 details
Itgb1Hsph1BioGRID30333137 details
Itgb1Pcbp2BioGRID30333137 details
Itgb1VclBioGRID30333137 details
Itgb1Fam120aBioGRID30333137 details
Itgb1VarsBioGRID30333137 details
Itgb1TprBioGRID30333137 details
Itgb1PhkbBioGRID30333137 details
Itgb1IarsBioGRID30333137 details
Itgb1Taok3BioGRID30333137 details
Itgb1Cps1BioGRID30333137 details
Itgb1Nckap1lBioGRID30333137 details
Itgb1Pitrm1BioGRID30333137 details
Itgb1Sf3a1BioGRID30333137 details
Itgb1Eif3cBioGRID30333137 details
Itgb1Myh9BioGRID30333137 details
Itgb1Prpf8BioGRID30333137 details
Itgb1Dync1h1BioGRID30333137 details
Itgb1Csf2rbI2D20802515 details
Itgb1Ccnd1I2D21242975 details
Itgb1WaslMINT21427700 details
Itgb1Dab2UniProt15734730 details
Itgb1EngMINT22940691 details
Itgb1Itga6BioGRID1833411 details
Itgb1Nmrk2BioGRID10613898 details
Itgb1PtprcBioGRID10906147 details
Itgb1Cdh17BioGRID10906147 32325033 details
Itgb1Itga3BioGRID10939329 25808491 details
Itgb1Sdc4BioGRID25202019 details
Itgb1KdrBioGRID28973887 details
Itgb1RelnBioGRID10939329 details
Itgb1FgrMINT19903482 details
Itgb1Abl1MINT19903482 details
Itgb1HckMINT19903482 details
Itgb1MTORBioGRID, IntAct26496610 details
Itgb1REPS2BioGRID, IntAct26496610 details
Itgb1ATP5POBioGRID, IntAct26496610 details
Itgb1PPP2R1BBioGRID, IntAct26496610 details
Itgb1ITGA3BioGRID, IntAct26496610 details
Itgb1CLPTM1LBioGRID, IntAct26496610 details
Itgb1SRPRBBioGRID, IntAct26496610 details
Itgb1SLC25A1BioGRID, IntAct26496610 details
Itgb1TIMM23BioGRID, IntAct26496610 details
Itgb1ATP2B1BioGRID, IntAct26496610 details
Itgb1HYOU1BioGRID, IntAct26496610 details
Itgb1COLGALT1BioGRID, IntAct26496610 details
Itgb1RPRD1BBioGRID, IntAct26496610 details
Itgb1PDIA3BioGRID, IntAct26496610 details
Itgb1SF1BioGRID, IntAct26496610 details
Itgb1ATP5MKBioGRID, IntAct26496610 details
Itgb1GALNT2BioGRID, IntAct26496610 details
Itgb1ATP5MEBioGRID, IntAct26496610 details
Itgb1FZD6BioGRID, IntAct26496610 details
Itgb1RBM10BioGRID, IntAct26496610 details
Itgb1CANXBioGRID, IntAct26496610 details
Itgb1UBAC2BioGRID, IntAct26496610 details
Itgb1CACNA2D1BioGRID, IntAct26496610 details
Itgb1TRIP13BioGRID, IntAct26496610 details
Itgb1IGF2RBioGRID, IntAct26496610 details
Itgb1FAM111BBioGRID, IntAct26496610 details
Itgb1ITGA2BioGRID, IntAct26496610 details
Itgb1ITGAVBioGRID, IntAct26496610 details
Itgb1FAT1BioGRID, IntAct26496610 details
Itgb1ARHGEF12BioGRID, IntAct26496610 details
Itgb1ITGA6BioGRID, IntAct26496610 details
Itgb1ITGA5BioGRID, IntAct26496610 details
Itgb1RBCK1BioGRID, IntAct26496610 details
Itgb1ITGA1BioGRID, IntAct26496610 details
Itgb1DDX42BioGRID, IntAct26496610 details
Itgb1SLC1A5BioGRID, IntAct26496610 details
Itgb1HSP90B1BioGRID, IntAct26496610 details
Itgb1SLC25A5BioGRID, IntAct26496610 details
Itgb1NCSTNDIP18942891 details
Itgb1PSEN1DIP18942891 details
Itgb1SSR3BioGRID26496610 details
Itgb1CHPT1BioGRID26496610 details
Itgb1PrkceBioGRID32325033 details
Itgb1Ptprn2BioGRID32325033 details
Itgb1Rab21BioGRID32325033 details
Itgb1Rab8bBioGRID32325033 details
Itgb1Tgm2BioGRID32325033 details
Itgb1Igfbp2BioGRID32325033 details
Itgb1Itga1BioGRID32325033 details
Itgb1Ptpn2BioGRID32325033 details
Itgb1CfdBioGRID30550785 details
Itgb1Fndc5BioGRID30550785 details
Itgb1UnkBioGRID25737280 details