Entity Details

Primary name Itgb2
Entity type gene
Source Source Link

Details

PrimaryID16414
RefseqGene
SymbolItgb2
Nameintegrin beta 2
Chromosome10
Location10 39.72 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-10
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsITB2_MOUSE

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001851 complement component C3b binding
GO:0002523 leukocyte migration involved in inflammatory response
GO:0005178 integrin binding
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006898 receptor-mediated endocytosis
GO:0006911 phagocytosis, engulfment
GO:0007155 cell adhesion
GO:0007159 leukocyte cell-cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016477 cell migration
GO:0019901 protein kinase binding
GO:0030101 natural killer cell activation
GO:0030369 ICAM-3 receptor activity
GO:0030593 neutrophil chemotaxis
GO:0031072 heat shock protein binding
GO:0031623 receptor internalization
GO:0032930 positive regulation of superoxide anion generation
GO:0033627 cell adhesion mediated by integrin
GO:0034113 heterotypic cell-cell adhesion
GO:0034687 integrin alphaL-beta2 complex
GO:0034688 integrin alphaM-beta2 complex
GO:0043113 receptor clustering
GO:0043235 receptor complex
GO:0043315 positive regulation of neutrophil degranulation
GO:0043542 endothelial cell migration
GO:0044853 plasma membrane raft
GO:0044877 protein-containing complex binding
GO:0045121 membrane raft
GO:0045123 cellular extravasation
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045766 positive regulation of angiogenesis
GO:0046872 metal ion binding
GO:0050730 regulation of peptidyl-tyrosine phosphorylation
GO:0050798 activated T cell proliferation
GO:0050839 cell adhesion molecule binding
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0071404 cellular response to low-density lipoprotein particle stimulus
GO:0097242 amyloid-beta clearance
GO:0098609 cell-cell adhesion
GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell
GO:1990266 neutrophil migration

Diseases

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Interactions

63 interactions

InteractorPartnerSourcesPublicationsLink
Itgb2Slc39a7IntAct15102471 details
Itgb2Prkar1aIntAct15102471 details
Itgb2Rpl19BioGRID30333137 details
Itgb2Sh3pxd2bBioGRID30333137 details
Itgb2Huwe1BioGRID30333137 details
Itgb2Ubr4BioGRID30333137 details
Itgb2Nop56BioGRID30333137 details
Itgb2Helz2BioGRID30333137 details
Itgb2Glo1BioGRID30333137 details
Itgb2Limd2BioGRID30333137 details
Itgb2Usp24BioGRID30333137 details
Itgb2FlnaBioGRID30333137 details
Itgb2FlncBioGRID30333137 details
Itgb2MyofBioGRID30333137 details
Itgb2PecrBioGRID30333137 details
Itgb2Xpo7BioGRID30333137 details
Itgb2Rpl6BioGRID30333137 details
Itgb2Gcn1BioGRID30333137 details
Itgb2Rpl15BioGRID30333137 details
Itgb2PlecBioGRID30333137 details
Itgb2Smc2BioGRID30333137 details
Itgb2Smc4BioGRID30333137 details
Itgb2Chd4BioGRID30333137 details
Itgb2ClpxBioGRID30333137 details
Itgb2Tln1BioGRID30333137 details
Itgb2Wnk1BioGRID30333137 details
Itgb2SonBioGRID30333137 details
Itgb2Birc6BioGRID30333137 details
Itgb2Itgb2BioGRID30333137 details
Itgb2C3BioGRID30333137 details
Itgb2Map1bBioGRID30333137 details
Itgb2Prdx3BioGRID30333137 details
Itgb2RdxBioGRID30333137 details
Itgb2Usp9xBioGRID30333137 details
Itgb2Tcerg1BioGRID30333137 details
Itgb2Dbn1BioGRID30333137 details
Itgb2Rpl4BioGRID30333137 details
Itgb2Sptbn1BioGRID30333137 details
Itgb2Nomo1BioGRID30333137 details
Itgb2TprBioGRID30333137 details
Itgb2Ubap2lBioGRID30333137 details
Itgb2FlnbBioGRID30333137 details
Itgb2Srrm2BioGRID30333137 details
Itgb2Utp25BioGRID30333137 details
Itgb2Taok3BioGRID30333137 details
Itgb2Plcg2BioGRID30333137 details
Itgb2Ipo11BioGRID30333137 details
Itgb2Sf3a1BioGRID30333137 details
Itgb2Pspc1BioGRID30333137 details
Itgb2Arpc5BioGRID30333137 details
Itgb2Dync1h1BioGRID30333137 details
Itgb2YwhabBioGRID18239087 details
Itgb2Eea1IntAct16892067 details
Itgb2Pag1IntAct26512138 details
Itgb2CblIntAct27474268 details
Itgb2Fancd2BioGRID28378742 details
Itgb2Glipr1BioGRID32325033 details
Itgb2ItgaxBioGRID32325033 details
Itgb2Laptm5BioGRID32325033 details
Itgb2Ncf4BioGRID32325033 details
Itgb2Samsn1BioGRID32325033 details
Itgb2Tlr13BioGRID32325033 details
Itgb2Tor1aip2BioGRID32325033 details