Entity Details

Primary name Itgb3
Entity type gene
Source Source Link

Details

PrimaryID16416
RefseqGene
SymbolItgb3
Nameintegrin beta 3
Chromosome11
Location11 67.84 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-11
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsITB3_MOUSE

GO terms

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GOName
GO:0001938 positive regulation of endothelial cell proliferation
GO:0001954 positive regulation of cell-matrix adhesion
GO:0001968 fibronectin binding
GO:0002020 protease binding
GO:0002687 positive regulation of leukocyte migration
GO:0003756 protein disulfide isomerase activity
GO:0005080 protein kinase C binding
GO:0005178 integrin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005925 focal adhesion
GO:0007044 cell-substrate junction assembly
GO:0007160 cell-matrix adhesion
GO:0007229 integrin-mediated signaling pathway
GO:0008277 regulation of G protein-coupled receptor signaling pathway
GO:0008305 integrin complex
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010595 positive regulation of endothelial cell migration
GO:0010628 positive regulation of gene expression
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010763 positive regulation of fibroblast migration
GO:0010888 negative regulation of lipid storage
GO:0014909 smooth muscle cell migration
GO:0014911 positive regulation of smooth muscle cell migration
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0016477 cell migration
GO:0019899 enzyme binding
GO:0030168 platelet activation
GO:0030334 regulation of cell migration
GO:0030335 positive regulation of cell migration
GO:0031258 lamellipodium membrane
GO:0031527 filopodium membrane
GO:0031528 microvillus membrane
GO:0031589 cell-substrate adhesion
GO:0032147 activation of protein kinase activity
GO:0032369 negative regulation of lipid transport
GO:0032587 ruffle membrane
GO:0032880 regulation of protein localization
GO:0032956 regulation of actin cytoskeleton organization
GO:0032991 protein-containing complex
GO:0033627 cell adhesion mediated by integrin
GO:0033630 positive regulation of cell adhesion mediated by integrin
GO:0033690 positive regulation of osteoblast proliferation
GO:0034113 heterotypic cell-cell adhesion
GO:0034446 substrate adhesion-dependent cell spreading
GO:0034679 integrin alpha9-beta1 complex
GO:0034683 integrin alphav-beta3 complex
GO:0035866 alphav-beta3 integrin-PKCalpha complex
GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex
GO:0035868 alphav-beta3 integrin-HMGB1 complex
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0038027 apolipoprotein A-I-mediated signaling pathway
GO:0042470 melanosome
GO:0042802 identical protein binding
GO:0043184 vascular endothelial growth factor receptor 2 binding
GO:0043235 receptor complex
GO:0043277 apoptotic cell clearance
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0045672 positive regulation of osteoclast differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045780 positive regulation of bone resorption
GO:0046718 viral entry into host cell
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048146 positive regulation of fibroblast proliferation
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0048858 cell projection morphogenesis
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050748 negative regulation of lipoprotein metabolic process
GO:0050839 cell adhesion molecule binding
GO:0050840 extracellular matrix binding
GO:0050919 negative chemotaxis
GO:0051279 regulation of release of sequestered calcium ion into cytosol
GO:0051611 regulation of serotonin uptake
GO:0060548 negative regulation of cell death
GO:0061097 regulation of protein tyrosine kinase activity
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070527 platelet aggregation
GO:0071133 alpha9-beta1 integrin-ADAM8 complex
GO:0072126 positive regulation of glomerular mesangial cell proliferation
GO:0098978 glutamatergic synapse
GO:0099149 regulation of postsynaptic neurotransmitter receptor internalization
GO:0099699 integral component of synaptic membrane
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1900731 positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway
GO:1903053 regulation of extracellular matrix organization
GO:1905598 negative regulation of low-density lipoprotein receptor activity
GO:2000406 positive regulation of T cell migration

Diseases

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Interactions

102 interactions

InteractorPartnerSourcesPublicationsLink
Itgb3Ubqln2BioGRID10549293 details
Itgb3GanabBioGRID30333137 details
Itgb3Cse1lBioGRID30333137 details
Itgb3Huwe1BioGRID30333137 details
Itgb3Usp8BioGRID30333137 details
Itgb3Xpo1BioGRID30333137 details
Itgb3Ubr4BioGRID30333137 details
Itgb3Trp53bp1BioGRID30333137 details
Itgb3Hcfc1BioGRID30333137 details
Itgb3FlnaBioGRID30333137 details
Itgb3Pdcd6ipBioGRID30333137 details
Itgb3Uba1BioGRID30333137 details
Itgb3Mov10BioGRID30333137 details
Itgb3FlncBioGRID30333137 details
Itgb3Diaph1BioGRID30333137 details
Itgb3MyofBioGRID30333137 details
Itgb3Dnase1l2BioGRID30333137 details
Itgb3PecrBioGRID30333137 details
Itgb3Gcn1BioGRID30333137 details
Itgb3PlecBioGRID30333137 details
Itgb3Man2c1BioGRID30333137 details
Itgb3Smc2BioGRID30333137 details
Itgb3Usp7BioGRID30333137 details
Itgb3Mthfd1BioGRID30333137 details
Itgb3Mcm4BioGRID30333137 details
Itgb3Iqgap1BioGRID30333137 details
Itgb3Tln1BioGRID30333137 details
Itgb3CopaBioGRID30333137 details
Itgb3OgfrBioGRID30333137 details
Itgb3Eif4g2BioGRID30333137 details
Itgb3SonBioGRID30333137 details
Itgb3Birc6BioGRID30333137 details
Itgb3Itgb3BioGRID30333137 details
Itgb3Man2b1BioGRID30333137 details
Itgb3Ap1b1BioGRID30333137 details
Itgb3Supt5BioGRID30333137 details
Itgb3Igf2bp1BioGRID30333137 details
Itgb3Hsp90b1BioGRID30333137 details
Itgb3NclBioGRID30333137 details
Itgb3Map1bBioGRID30333137 details
Itgb3Ap2a2BioGRID30333137 details
Itgb3CblBioGRID30333137 details
Itgb3Eif3aBioGRID30333137 details
Itgb3Dnm2BioGRID30333137 details
Itgb3Hspa4lBioGRID30333137 details
Itgb3Usp9xBioGRID30333137 details
Itgb3Mcm2BioGRID30333137 details
Itgb3Mcm6BioGRID30333137 details
Itgb3PrkdcBioGRID30333137 details
Itgb3Eif5bBioGRID30333137 details
Itgb3NpeppsBioGRID30333137 details
Itgb3Atxn2lBioGRID30333137 details
Itgb3Psmd2BioGRID30333137 details
Itgb3Psmd1BioGRID30333137 details
Itgb3Sec24aBioGRID30333137 details
Itgb3Esyt1BioGRID30333137 details
Itgb3Myh10BioGRID30333137 details
Itgb3PfasBioGRID30333137 details
Itgb3Ewsr1BioGRID30333137 details
Itgb3CltcBioGRID30333137 details
Itgb3Caprin1BioGRID30333137 details
Itgb3Hsph1BioGRID30333137 details
Itgb3Kif5bBioGRID30333137 details
Itgb3Sptbn1BioGRID30333137 details
Itgb3VclBioGRID30333137 details
Itgb3Nomo1BioGRID30333137 details
Itgb3Snrnp200BioGRID30333137 details
Itgb3Uggt1BioGRID30333137 details
Itgb3Cand1BioGRID30333137 details
Itgb3VarsBioGRID30333137 details
Itgb3TprBioGRID30333137 details
Itgb3Tecpr1BioGRID30333137 details
Itgb3FlnbBioGRID30333137 details
Itgb3AarsBioGRID30333137 details
Itgb3Ipo5BioGRID30333137 details
Itgb3Srrm2BioGRID30333137 details
Itgb3IarsBioGRID30333137 details
Itgb3Ipo11BioGRID30333137 details
Itgb3Sf3a1BioGRID30333137 details
Itgb3Eif3cBioGRID30333137 details
Itgb3Myh9BioGRID30333137 details
Itgb3Atp1a1BioGRID30333137 details
Itgb3Oas3BioGRID30333137 details
Itgb3SfpqBioGRID30333137 details
Itgb3Prpf8BioGRID30333137 details
Itgb3Ipo7BioGRID30333137 details
Itgb3Upf1BioGRID30333137 details
Itgb3Dync1h1BioGRID30333137 details
Itgb3Copb1BioGRID30333137 details
Itgb3Vav3BioGRID30333137 details
Itgb3Suclg1BioGRID30333137 details
Itgb3Ilf3BioGRID30333137 details
Itgb3Itga5mbinfo11756480 details
Itgb3EgfrDIP17606926 details
Itgb3SrcDIP18840695 details
Itgb3PrkcaBioGRID16014375 details
Itgb3CskBioGRID24558484 details
Itgb3Pla2g4aBioGRID18840708 details
Itgb3PrkcbBioGRID18840708 details
Itgb3Itgavmbinfo17485491 details
Itgb3Prkd1mbinfo17485491 details
Itgb3YWHAZBioGRID29530978 details