Entity Details

Primary name Jun
Entity type gene
Source Source Link

Details

PrimaryID16476
RefseqGene
SymbolJun
Namejun proto-oncogene
Chromosome4
Location4 43.34 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsJUN_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000791 euchromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001774 microglial cell activation
GO:0001836 release of cytochrome c from mitochondria
GO:0001889 liver development
GO:0001938 positive regulation of endothelial cell proliferation
GO:0003151 outflow tract morphogenesis
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005096 GTPase activator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007265 Ras protein signal transduction
GO:0007568 aging
GO:0007612 learning
GO:0007623 circadian rhythm
GO:0008134 transcription factor binding
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0009314 response to radiation
GO:0009987 cellular process
GO:0010634 positive regulation of epithelial cell migration
GO:0017053 transcription repressor complex
GO:0019899 enzyme binding
GO:0030224 monocyte differentiation
GO:0031103 axon regeneration
GO:0031625 ubiquitin protein ligase binding
GO:0031953 negative regulation of protein autophosphorylation
GO:0032496 response to lipopolysaccharide
GO:0034097 response to cytokine
GO:0034614 cellular response to reactive oxygen species
GO:0035026 leading edge cell differentiation
GO:0035497 cAMP response element binding
GO:0035976 transcription factor AP-1 complex
GO:0035994 response to muscle stretch
GO:0042127 regulation of cell population proliferation
GO:0042493 response to drug
GO:0042542 response to hydrogen peroxide
GO:0042802 identical protein binding
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043392 negative regulation of DNA binding
GO:0043524 negative regulation of neuron apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0043922 negative regulation by host of viral transcription
GO:0043923 positive regulation by host of viral transcription
GO:0044389 ubiquitin-like protein ligase binding
GO:0044877 protein-containing complex binding
GO:0045657 positive regulation of monocyte differentiation
GO:0045740 positive regulation of DNA replication
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048146 positive regulation of fibroblast proliferation
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0051365 cellular response to potassium ion starvation
GO:0051591 response to cAMP
GO:0051726 regulation of cell cycle
GO:0051899 membrane depolarization
GO:0060395 SMAD protein signal transduction
GO:0061029 eyelid development in camera-type eye
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070412 R-SMAD binding
GO:0071276 cellular response to cadmium ion
GO:0071277 cellular response to calcium ion
GO:0071837 HMG box domain binding
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000144 positive regulation of DNA-templated transcription, initiation

Diseases

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Interactions

44 interactions

InteractorPartnerSourcesPublicationsLink
JunMapk8BioGRID, MINT10581243 10748240 12223491 15218018 15288121 15767678 17158449 17255944 17276034 21538482 9687507 details
JunFosBioGRID, MINT12145309 15867431 1631061 21478324 details
JunJunBioGRID, MINT1631061 21262356 details
JunESR1UniProt11477071 details
JunHhexBioGRID11551904 details
JunHoxc8BioGRID11551904 details
JunHoxa9BioGRID11551904 details
JunEn1BioGRID11551904 details
JunAtf4BioGRID20211142 details
JunBarx2BioGRID20211142 details
JunMafbBioGRID12798298 20211142 details
JunStat3BioGRID20211142 details
JunSmad3BioGRID22610349 details
JunCops5BioGRID11704659 details
JunSnapc5BioGRID15867431 details
JunCasp9BioGRID23678002 details
JunItgb1BioGRID30333137 details
JunCdk6IntAct23948297 details
JunAtf3BioGRID, IntAct20211142 21304988 details
JunSmarca2BioGRID11053448 details
JunSmarcb1BioGRID11053448 details
JunItchBioGRID16901904 details
JunEsr1BioGRID19605792 details
JunTcf4BioGRID16007074 details
JunCtnnb1BioGRID16007074 details
JunRelaBioGRID21262356 details
JunSp1BioGRID21262356 details
JunCreb1BioGRID21262356 details
JunCyldBioGRID21478324 details
JunNUMBBioGRID9632782 details
JunSirt1BioGRID18676681 20042607 details
JunBrca1BioGRID16807234 details
JunBag1BioGRID20516211 details
JunSpi1BioGRID19181746 details
JunMecomDIP22308434 details
JunSRYBioGRID16582099 details
JunSox8BioGRID16582099 details
JunZbtb7bBioGRID32098917 details
JunSox17BioGRID31823782 details
JunGfi1IntAct23410974 details
JunVegfaIntAct23948297 details
JunFoxo3IntAct24298014 details
JunIl23aIntAct19592489 details
JunCpeb1BioGRID18716208 details