Entity Details

Primary name Arhgef2
Entity type gene
Source Source Link

Details

PrimaryID16800
RefseqGene
SymbolArhgef2
Namerho/rac guanine nucleotide exchange factor (GEF) 2
Chromosome3
Location3
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsARHG2_MOUSE

GO terms

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GOName
GO:0000132 establishment of mitotic spindle orientation
GO:0000902 cell morphogenesis
GO:0002102 podosome
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005819 spindle
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005923 bicellular tight junction
GO:0007015 actin filament organization
GO:0007026 negative regulation of microtubule depolymerization
GO:0008017 microtubule binding
GO:0014069 postsynaptic density
GO:0031267 small GTPase binding
GO:0031410 cytoplasmic vesicle
GO:0031982 vesicle
GO:0032587 ruffle membrane
GO:0032755 positive regulation of interleukin-6 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032991 protein-containing complex
GO:0035023 regulation of Rho protein signal transduction
GO:0035556 intracellular signal transduction
GO:0043025 neuronal cell body
GO:0043198 dendritic shaft
GO:0045087 innate immune response
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050768 negative regulation of neurogenesis
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0055059 asymmetric neuroblast division
GO:0071225 cellular response to muramyl dipeptide
GO:0071802 negative regulation of podosome assembly
GO:0098978 glutamatergic synapse
GO:0099092 postsynaptic density, intracellular component
GO:2001224 positive regulation of neuron migration

Diseases

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Interactions

63 interactions

InteractorPartnerSourcesPublicationsLink
Arhgef2RHOABioGRID, IntAct24525234 32203420 details
Arhgef2Asap1BioGRID18685082 21352810 32325033 details
Arhgef2UbcBioGRID28190767 details
Arhgef2RhobMINT16917499 details
Arhgef2Ksr1IntAct24525234 details
Arhgef2Ppp1r9bBioGRID15996550 details
Arhgef2Ogg1BioGRID22057269 details
Arhgef2YwhabIntAct16635246 details
Arhgef2YWHAZIntAct16959763 details
Arhgef2Trpm7IntAct24855944 details
Arhgef2Rab38IntAct26885862 details
Arhgef2Cyfip1BioGRID, IntAct28671696 details
Arhgef2Fxr1BioGRID, IntAct28671696 details
Arhgef2Mycbp2BioGRID, IntAct28671696 details
Arhgef2Pex5lBioGRID, IntAct28671696 details
Arhgef2TnikBioGRID, IntAct28671696 details
Arhgef2Tsc1BioGRID, IntAct28671696 details
Arhgef2SORL1BioGRID, IntAct32203420 details
Arhgef2PPP6R3BioGRID, IntAct32203420 details
Arhgef2PPP6CBioGRID, IntAct32203420 details
Arhgef2CKMT1BBioGRID, IntAct32203420 details
Arhgef2CKMT1AIntAct32203420 details
Arhgef2ANKRD28BioGRID, IntAct32203420 details
Arhgef2YwhazBioGRID16959763 details
Arhgef2Fancd2BioGRID28378742 details
Arhgef2Atg16l1BioGRID30196744 details
Arhgef2CapzbBioGRID32325033 details
Arhgef2SelenohBioGRID32325033 details
Arhgef2Mark4BioGRID32325033 details
Arhgef2Wasf1BioGRID32325033 details
Arhgef2Mapk1BioGRID32325033 details
Arhgef2Tpm3BioGRID32325033 details
Arhgef2DbnlBioGRID32325033 details
Arhgef2Mapk3BioGRID32325033 details
Arhgef2Ppp6cBioGRID32325033 details
Arhgef2RhoaBioGRID32325033 details
Arhgef2Tpm4BioGRID32325033 details
Arhgef2Arhgap21BioGRID32325033 details
Arhgef2Arhgap26BioGRID32325033 details
Arhgef2Akap13BioGRID32325033 details
Arhgef2Arhgap40BioGRID32325033 details
Arhgef2Arhgap42BioGRID32325033 details
Arhgef2BblnBioGRID32325033 details
Arhgef2Dab2ipBioGRID32325033 details
Arhgef2Eps8BioGRID32325033 details
Arhgef2Fcho2BioGRID32325033 details
Arhgef2Prickle1BioGRID32325033 details
Arhgef2Syngap1BioGRID32325033 details
Arhgef2UgcgBioGRID32325033 details
Arhgef2Arhgef7BioGRID32325033 details
Arhgef2Chn2BioGRID32325033 details
Arhgef2Fermt3BioGRID32325033 details
Arhgef2Fgd4BioGRID32325033 details
Arhgef2Pak4BioGRID32325033 details
Arhgef2Pdlim5BioGRID32325033 details
Arhgef2Prickle2BioGRID32325033 details
Arhgef2Sorbs1BioGRID32325033 details
Arhgef2Sorbs3BioGRID32325033 details
Arhgef2Srgap1BioGRID32325033 details
Arhgef2Strip2BioGRID32325033 details
Arhgef2VclBioGRID32325033 details
Arhgef2CDC42BPABioGRID32203420 details
Arhgef2FUBP1BioGRID32203420 details