Entity Details

Primary name Lhx2
Entity type gene
Source Source Link

Details

PrimaryID16870
RefseqGene
SymbolLhx2
NameLIM homeobox protein 2
Chromosome2
Location2
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-03-23
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsLHX2_MOUSE

GO terms

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GOName
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001843 neural tube closure
GO:0001942 hair follicle development
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0007420 brain development
GO:0007498 mesoderm development
GO:0008134 transcription factor binding
GO:0009953 dorsal/ventral pattern formation
GO:0021537 telencephalon development
GO:0021772 olfactory bulb development
GO:0021978 telencephalon regionalization
GO:0021987 cerebral cortex development
GO:0022008 neurogenesis
GO:0030182 neuron differentiation
GO:0043565 sequence-specific DNA binding
GO:0045199 maintenance of epithelial cell apical/basal polarity
GO:0045814 negative regulation of gene expression, epigenetic
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048646 anatomical structure formation involved in morphogenesis
GO:0048675 axon extension
GO:0050768 negative regulation of neurogenesis
GO:0060041 retina development in camera-type eye
GO:2000179 positive regulation of neural precursor cell proliferation
GO:2000678 negative regulation of transcription regulatory region DNA binding

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
Lhx2Ldb2BioGRID, IntAct20211142 details
Lhx2Ldb1BioGRID, IntAct20211142 details
Lhx2MrtfaBioGRID, IntAct20211142 details
Lhx2Gmeb2BioGRID, IntAct20211142 details
Lhx2Ssbp2BioGRID, IntAct20211142 details
Lhx2Ssbp3BioGRID, IntAct20211142 details