Entity Details

Primary name Lrp6
Entity type gene
Source Source Link

Details

PrimaryID16974
RefseqGene
SymbolLrp6
Namelow density lipoprotein receptor-related protein 6
Chromosome6
Location6 65.37 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-28
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsLRP6_MOUSE

GO terms

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GOName
GO:0001702 gastrulation with mouth forming second
GO:0001756 somitogenesis
GO:0001843 neural tube closure
GO:0001933 negative regulation of protein phosphorylation
GO:0001947 heart looping
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0003344 pericardium morphogenesis
GO:0003401 axis elongation
GO:0005041 low-density lipoprotein particle receptor activity
GO:0005102 signaling receptor binding
GO:0005109 frizzled binding
GO:0005769 early endosome
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006469 negative regulation of protein kinase activity
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007268 chemical synaptic transmission
GO:0009880 embryonic pattern specification
GO:0009950 dorsal/ventral axis specification
GO:0009952 anterior/posterior pattern specification
GO:0009986 cell surface
GO:0010976 positive regulation of neuron projection development
GO:0014029 neural crest formation
GO:0014033 neural crest cell differentiation
GO:0015026 coreceptor activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016055 Wnt signaling pathway
GO:0017147 Wnt-protein binding
GO:0019210 kinase inhibitor activity
GO:0019534 toxin transmembrane transporter activity
GO:0021587 cerebellum morphogenesis
GO:0021794 thalamus development
GO:0021795 cerebral cortex cell migration
GO:0021861 forebrain radial glial cell differentiation
GO:0021872 forebrain generation of neurons
GO:0021874 Wnt signaling pathway involved in forebrain neuroblast division
GO:0021915 neural tube development
GO:0021943 formation of radial glial scaffolds
GO:0021987 cerebral cortex development
GO:0030278 regulation of ossification
GO:0030326 embryonic limb morphogenesis
GO:0030900 forebrain development
GO:0030901 midbrain development
GO:0030917 midbrain-hindbrain boundary development
GO:0031410 cytoplasmic vesicle
GO:0034185 apolipoprotein binding
GO:0034392 negative regulation of smooth muscle cell apoptotic process
GO:0035108 limb morphogenesis
GO:0035115 embryonic forelimb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0035261 external genitalia morphogenesis
GO:0036342 post-anal tail morphogenesis
GO:0042074 cell migration involved in gastrulation
GO:0042127 regulation of cell population proliferation
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042733 embryonic digit morphogenesis
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042813 Wnt-activated receptor activity
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0045121 membrane raft
GO:0045202 synapse
GO:0045599 negative regulation of fat cell differentiation
GO:0045778 positive regulation of ossification
GO:0045780 positive regulation of bone resorption
GO:0045787 positive regulation of cell cycle
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046849 bone remodeling
GO:0048596 embryonic camera-type eye morphogenesis
GO:0048699 generation of neurons
GO:0048705 skeletal system morphogenesis
GO:0050680 negative regulation of epithelial cell proliferation
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051593 response to folic acid
GO:0060021 roof of mouth development
GO:0060026 convergent extension
GO:0060042 retina morphogenesis in camera-type eye
GO:0060059 embryonic retina morphogenesis in camera-type eye
GO:0060070 canonical Wnt signaling pathway
GO:0060284 regulation of cell development
GO:0060325 face morphogenesis
GO:0060349 bone morphogenesis
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0060535 trachea cartilage morphogenesis
GO:0060596 mammary placode formation
GO:0060603 mammary gland duct morphogenesis
GO:0061310 canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development
GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation
GO:0071397 cellular response to cholesterol
GO:0071542 dopaminergic neuron differentiation
GO:0071901 negative regulation of protein serine/threonine kinase activity
GO:0071936 coreceptor activity involved in Wnt signaling pathway
GO:0072659 protein localization to plasma membrane
GO:0090009 primitive streak formation
GO:0090118 receptor-mediated endocytosis involved in cholesterol transport
GO:0090244 Wnt signaling pathway involved in somitogenesis
GO:0090245 axis elongation involved in somitogenesis
GO:0098609 cell-cell adhesion
GO:0110135 Norrin signaling pathway
GO:1990851 Wnt-Frizzled-LRP5/6 complex
GO:1990909 Wnt signalosome
GO:2000051 negative regulation of non-canonical Wnt signaling pathway
GO:2000149 negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis
GO:2000151 negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
GO:2000162 negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis
GO:2000164 negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis
GO:2000166 negative regulation of planar cell polarity pathway involved in pericardium morphogenesis
GO:2000168 negative regulation of planar cell polarity pathway involved in neural tube closure

Diseases

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