Entity Details

Primary name Mcl1
Entity type gene
Source Source Link

Details

PrimaryID17210
RefseqGene
SymbolMcl1
Namemyeloid cell leukemia sequence 1
Chromosome3
Location3 40.74 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsMCL1_MOUSE

GO terms

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GOName
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
GO:0007275 multicellular organism development
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008637 apoptotic mitochondrial changes
GO:0010507 negative regulation of autophagy
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030154 cell differentiation
GO:0034097 response to cytokine
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0044877 protein-containing complex binding
GO:0046982 protein heterodimerization activity
GO:0046983 protein dimerization activity
GO:0051400 BH domain binding
GO:0051434 BH3 domain binding
GO:0097136 Bcl-2 family protein complex
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
GO:2000811 negative regulation of anoikis
GO:2001020 regulation of response to DNA damage stimulus
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway

Diseases

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