Entity Details

Primary name SH2B1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionQ91ZM2
EntryNameSH2B1_MOUSE
FullNameSH2B adapter protein 1
TaxID10090
Evidenceevidence at protein level
Length756
SequenceStatuscomplete
DateCreated2008-03-18
DateModified2021-06-02

Ontological Relatives

GenesSh2b1

GO terms

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GOName
GO:0001726 ruffle
GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0030032 lamellipodium assembly
GO:0035556 intracellular signal transduction
GO:0045840 positive regulation of mitotic nuclear division
GO:0060391 positive regulation of SMAD protein signal transduction
GO:2000278 regulation of DNA biosynthetic process

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR015012 Phenylalanine zipperDomainDomain
IPR030521 SH2B adapter protein 1FamilyFamily
IPR030523 SH2B adapter proteinFamilyFamily
IPR035057 SH2B1, SH2 domainDomainDomain
IPR036290 Phenylalanine zipper superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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