Entity Details

Primary name DKK1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionO54908
EntryNameDKK1_MOUSE
FullNameDickkopf-related protein 1
TaxID10090
Evidenceevidence at protein level
Length272
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesDkk1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000904 cell morphogenesis involved in differentiation
GO:0001706 endoderm formation
GO:0001707 mesoderm formation
GO:0001942 hair follicle development
GO:0002090 regulation of receptor internalization
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0007492 endoderm development
GO:0007611 learning or memory
GO:0010628 positive regulation of gene expression
GO:0010977 negative regulation of neuron projection development
GO:0030111 regulation of Wnt signaling pathway
GO:0030178 negative regulation of Wnt signaling pathway
GO:0030279 negative regulation of ossification
GO:0030326 embryonic limb morphogenesis
GO:0030514 negative regulation of BMP signaling pathway
GO:0030900 forebrain development
GO:0032091 negative regulation of protein binding
GO:0032526 response to retinoic acid
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0039706 co-receptor binding
GO:0042662 negative regulation of mesodermal cell fate specification
GO:0042663 regulation of endodermal cell fate specification
GO:0043066 negative regulation of apoptotic process
GO:0043507 positive regulation of JUN kinase activity
GO:0048019 receptor antagonist activity
GO:0050750 low-density lipoprotein particle receptor binding
GO:0050807 regulation of synapse organization
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0060173 limb development
GO:0060323 head morphogenesis
GO:0060325 face morphogenesis
GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0061743 motor learning
GO:0090082 positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090244 Wnt signaling pathway involved in somitogenesis
GO:0090647 modulation of age-related behavioral decline
GO:1901296 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
GO:1902949 positive regulation of tau-protein kinase activity
GO:1904723 negative regulation of Wnt-Frizzled-LRP5/6 complex assembly
GO:1904958 positive regulation of midbrain dopaminergic neuron differentiation
GO:1905607 negative regulation of presynapse assembly
GO:2000726 negative regulation of cardiac muscle cell differentiation

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR006796 Dickkopf, N-terminal cysteine-richDomainDomain
IPR039863 Dickkopf-like proteinFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DKK1_MOUSELRP6_MOUSEBioGRID16126904 18505367 32325033 details