Entity Details

Primary name Nck1
Entity type gene
Source Source Link

Details

PrimaryID17973
RefseqGene
SymbolNck1
Namenon-catalytic region of tyrosine kinase adaptor protein 1
Chromosome9
Location9
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsNCK1_MOUSE

GO terms

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GOName
GO:0000164 protein phosphatase type 1 complex
GO:0004860 protein kinase inhibitor activity
GO:0005102 signaling receptor binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006930 substrate-dependent cell migration, cell extension
GO:0007015 actin filament organization
GO:0010976 positive regulation of neuron projection development
GO:0012506 vesicle membrane
GO:0016477 cell migration
GO:0019904 protein domain specific binding
GO:0030032 lamellipodium assembly
GO:0030334 regulation of cell migration
GO:0030674 protein-macromolecule adaptor activity
GO:0030838 positive regulation of actin filament polymerization
GO:0030971 receptor tyrosine kinase binding
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress
GO:0042102 positive regulation of T cell proliferation
GO:0042110 T cell activation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0046875 ephrin receptor binding
GO:0048013 ephrin receptor signaling pathway
GO:0051707 response to other organism
GO:0060548 negative regulation of cell death
GO:0070262 peptidyl-serine dephosphorylation
GO:0071074 eukaryotic initiation factor eIF2 binding
GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1903676 positive regulation of cap-dependent translational initiation
GO:1903679 positive regulation of cap-independent translational initiation
GO:1903898 negative regulation of PERK-mediated unfolded protein response
GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
GO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Diseases

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Interactions

58 interactions

InteractorPartnerSourcesPublicationsLink
Nck1Pik3ap1IntAct15102471 details
Nck1Map2k2IntAct15102471 details
Nck1Psrc1BioGRID, IntAct15102471 32325033 details
Nck1CalrIntAct15102471 details
Nck1Khdrbs1IntAct15102471 details
Nck1Map4k4IntAct15102471 details
Nck1WasIntAct15102471 details
Nck1Wipf1IntAct15102471 details
Nck1Abl1BioGRID, IntAct10967110 15148308 details
Nck1EPHB1MINT9430661 details
Nck1Dok1BioGRID, IntAct15148308 20697350 details
Nck1Tnk2BioGRID, DIP16777958 details
Nck1CblBioGRID32325033 7517397 8635998 details
Nck1KdrBioGRID16966330 details
Nck1FynBioGRID16966330 details
Nck1Dab1BioGRID15110774 details
Nck1Dok2BioGRID, IntAct20697350 details
Nck1Pag1IntAct26512138 details
Nck1Asap1BioGRID32325033 details
Nck1Abi1BioGRID32325033 details
Nck1Csde1BioGRID32325033 details
Nck1Map4BioGRID32325033 details
Nck1Nckap1BioGRID32325033 details
Nck1NfascBioGRID32325033 details
Nck1Pak3BioGRID32325033 details
Nck1Rpl13BioGRID32325033 details
Nck1Shroom2BioGRID32325033 details
Nck1Wasf1BioGRID32325033 details
Nck1Ptpn4BioGRID32325033 details
Nck1Arhgef7BioGRID32325033 details
Nck1Gstz1BioGRID32325033 details
Nck1Mink1BioGRID32325033 details
Nck1Asap2BioGRID32325033 details
Nck1Brk1BioGRID32325033 details
Nck1CastBioGRID32325033 details
Nck1CrklBioGRID32325033 details
Nck1Cyfip2BioGRID32325033 details
Nck1Eif2s2BioGRID32325033 details
Nck1Gad1BioGRID32325033 details
Nck1GnsBioGRID32325033 details
Nck1GopcBioGRID32325033 details
Nck1H1f4BioGRID32325033 details
Nck1OxtBioGRID32325033 details
Nck1Pak2BioGRID32325033 details
Nck1Pfn1BioGRID32325033 details
Nck1Plcg1BioGRID32325033 details
Nck1Snx12BioGRID32325033 details
Nck1Snx17BioGRID32325033 details
Nck1Snx27BioGRID32325033 details
Nck1Ubash3bBioGRID32325033 details
Nck1Sema7aBioGRID32325033 details
Nck1Fhl5BioGRID32325033 details
Nck1Magi2BioGRID32325033 details
Nck1Atp2a3BioGRID32325033 details
Nck1Nedd9BioGRID32325033 details
Nck1Scarf2BioGRID32325033 details
Nck1SelenonBioGRID32325033 details
Nck1Tulp1BioGRID32325033 details