Entity Details

Primary name Nek2
Entity type gene
Source Source Link

Details

PrimaryID18005
RefseqGene
SymbolNek2
NameNIMA (never in mitosis gene a)-related expressed kinase 2
Chromosome1
Location1 96.94 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-10-25
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsNEK2_MOUSE

GO terms

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GOName
GO:0000070 mitotic sister chromatid segregation
GO:0000776 kinetochore
GO:0000794 condensed nuclear chromosome
GO:0000922 spindle pole
GO:0001824 blastocyst development
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005874 microtubule
GO:0006468 protein phosphorylation
GO:0007059 chromosome segregation
GO:0019903 protein phosphatase binding
GO:0030496 midbody
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0032991 protein-containing complex
GO:0043392 negative regulation of DNA binding
GO:0046602 regulation of mitotic centrosome separation
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0051299 centrosome separation
GO:0051301 cell division
GO:0051321 meiotic cell cycle
GO:0051973 positive regulation of telomerase activity
GO:0051988 regulation of attachment of spindle microtubules to kinetochore
GO:0090307 mitotic spindle assembly
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1903126 negative regulation of centriole-centriole cohesion
GO:1904355 positive regulation of telomere capping

Diseases

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Interactions

38 interactions

InteractorPartnerSourcesPublicationsLink
Nek2Ppp1caBioGRID, IntAct17274640 details
Nek2PPP1R2BioGRID12221103 details
Nek2ACAD8BioGRID, IntAct20360068 details
Nek2NEK2BioGRID, IntAct20360068 details
Nek2FLNABioGRID, IntAct26496610 details
Nek2KNL1BioGRID, IntAct26496610 details
Nek2PRPF18BioGRID, IntAct26496610 details
Nek2CDC16BioGRID, IntAct26496610 details
Nek2PRKAR2ABioGRID, IntAct26496610 details
Nek2ANAPC7BioGRID, IntAct26496610 details
Nek2KIAA2013BioGRID, IntAct26496610 details
Nek2MTHFD2BioGRID, IntAct26496610 details
Nek2FOXM1BioGRID, IntAct26496610 details
Nek2CDCA3BioGRID, IntAct26496610 details
Nek2TFB2MBioGRID, IntAct26496610 details
Nek2KIFC1BioGRID, IntAct26496610 details
Nek2ANAPC1BioGRID, IntAct26496610 details
Nek2MKNK1BioGRID, IntAct26496610 details
Nek2CDC26BioGRID, IntAct26496610 details
Nek2PDFBioGRID, IntAct26496610 details
Nek2EME1BioGRID, IntAct26496610 details
Nek2DLGAP4BioGRID, IntAct26496610 details
Nek2HMCESBioGRID, IntAct26496610 details
Nek2PDIA3BioGRID, IntAct26496610 details
Nek2KIF24BioGRID, IntAct26496610 details
Nek2DEPDC1BioGRID, IntAct26496610 details
Nek2CTSCBioGRID, IntAct26496610 details
Nek2CDC23BioGRID, IntAct26496610 details
Nek2ITM2BBioGRID, IntAct26496610 details
Nek2FZR1BioGRID, IntAct26496610 details
Nek2LTN1BioGRID, IntAct26496610 details
Nek2CDC27BioGRID, IntAct26496610 details
Nek2IARS2BioGRID, IntAct26496610 details
Nek2DNM1LBioGRID, IntAct26496610 details
Nek2PSMD5BioGRID, IntAct26496610 details
Nek2MRRFBioGRID, IntAct26496610 details
Nek2WDR46BioGRID26496610 details
Nek2BBXBioGRID26496610 details