Entity Details

Primary name Nf1
Entity type gene
Source Source Link

Details

PrimaryID18015
RefseqGene
SymbolNf1
Nameneurofibromin 1
Chromosome11
Location11 46.74 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsNF1_MOUSE

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001649 osteoblast differentiation
GO:0001656 metanephros development
GO:0001666 response to hypoxia
GO:0001889 liver development
GO:0001937 negative regulation of endothelial cell proliferation
GO:0001938 positive regulation of endothelial cell proliferation
GO:0001952 regulation of cell-matrix adhesion
GO:0001953 negative regulation of cell-matrix adhesion
GO:0005096 GTPase activator activity
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006469 negative regulation of protein kinase activity
GO:0007154 cell communication
GO:0007265 Ras protein signal transduction
GO:0007406 negative regulation of neuroblast proliferation
GO:0007420 brain development
GO:0007422 peripheral nervous system development
GO:0007507 heart development
GO:0007519 skeletal muscle tissue development
GO:0008017 microtubule binding
GO:0008285 negative regulation of cell population proliferation
GO:0008429 phosphatidylethanolamine binding
GO:0008542 visual learning
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0010468 regulation of gene expression
GO:0010976 positive regulation of neuron projection development
GO:0014044 Schwann cell development
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016525 negative regulation of angiogenesis
GO:0021510 spinal cord development
GO:0021764 amygdala development
GO:0021897 forebrain astrocyte development
GO:0021915 neural tube development
GO:0021987 cerebral cortex development
GO:0022011 myelination in peripheral nervous system
GO:0030036 actin cytoskeleton organization
GO:0030198 extracellular matrix organization
GO:0030199 collagen fibril organization
GO:0030325 adrenal gland development
GO:0030336 negative regulation of cell migration
GO:0030424 axon
GO:0030425 dendrite
GO:0031210 phosphatidylcholine binding
GO:0032228 regulation of synaptic transmission, GABAergic
GO:0032991 protein-containing complex
GO:0034605 cellular response to heat
GO:0035021 negative regulation of Rac protein signal transduction
GO:0042060 wound healing
GO:0042127 regulation of cell population proliferation
GO:0042308 negative regulation of protein import into nucleus
GO:0043005 neuron projection
GO:0043065 positive regulation of apoptotic process
GO:0043087 regulation of GTPase activity
GO:0043407 negative regulation of MAP kinase activity
GO:0043408 regulation of MAPK cascade
GO:0043409 negative regulation of MAPK cascade
GO:0043473 pigmentation
GO:0043525 positive regulation of neuron apoptotic process
GO:0043535 regulation of blood vessel endothelial cell migration
GO:0043547 positive regulation of GTPase activity
GO:0045124 regulation of bone resorption
GO:0045545 syndecan binding
GO:0045664 regulation of neuron differentiation
GO:0045671 negative regulation of osteoclast differentiation
GO:0045685 regulation of glial cell differentiation
GO:0045762 positive regulation of adenylate cyclase activity
GO:0045765 regulation of angiogenesis
GO:0046580 negative regulation of Ras protein signal transduction
GO:0046929 negative regulation of neurotransmitter secretion
GO:0048147 negative regulation of fibroblast proliferation
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0048485 sympathetic nervous system development
GO:0048593 camera-type eye morphogenesis
GO:0048712 negative regulation of astrocyte differentiation
GO:0048715 negative regulation of oligodendrocyte differentiation
GO:0048745 smooth muscle tissue development
GO:0048820 hair follicle maturation
GO:0048844 artery morphogenesis
GO:0048853 forebrain morphogenesis
GO:0050890 cognition
GO:0061534 gamma-aminobutyric acid secretion, neurotransmission
GO:0061535 glutamate secretion, neurotransmission
GO:0098597 observational learning
GO:0098793 presynapse
GO:1900271 regulation of long-term synaptic potentiation
GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Diseases

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