Entity Details

Primary name Nkx2-2
Entity type gene
Source Source Link

Details

PrimaryID18088
RefseqGene
SymbolNkx2-2
NameNK2 homeobox 2
Chromosome2
Location2 72.63 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-06-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsNKX22_MOUSE

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003323 type B pancreatic cell development
GO:0003326 pancreatic A cell fate commitment
GO:0003327 type B pancreatic cell fate commitment
GO:0003329 pancreatic PP cell fate commitment
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007224 smoothened signaling pathway
GO:0007399 nervous system development
GO:0008134 transcription factor binding
GO:0009749 response to glucose
GO:0010628 positive regulation of gene expression
GO:0014003 oligodendrocyte development
GO:0021522 spinal cord motor neuron differentiation
GO:0021529 spinal cord oligodendrocyte cell differentiation
GO:0021530 spinal cord oligodendrocyte cell fate specification
GO:0021554 optic nerve development
GO:0030154 cell differentiation
GO:0031018 endocrine pancreas development
GO:0032570 response to progesterone
GO:0043565 sequence-specific DNA binding
GO:0045597 positive regulation of cell differentiation
GO:0045665 negative regulation of neuron differentiation
GO:0045666 positive regulation of neuron differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048468 cell development
GO:0048565 digestive tract development
GO:0048665 neuron fate specification
GO:0048708 astrocyte differentiation
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0060580 ventral spinal cord interneuron fate determination

Diseases

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Interactions

8 interactions