Entity Details

Primary name NR1I2_MOUSE
Entity type UniProt
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Details

AccessionO54915
EntryNameNR1I2_MOUSE
FullNameNuclear receptor subfamily 1 group I member 2
TaxID10090
Evidenceevidence at protein level
Length431
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesNr1i2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006805 xenobiotic metabolic process
GO:0008144 drug binding
GO:0008270 zinc ion binding
GO:0010628 positive regulation of gene expression
GO:0016604 nuclear body
GO:0016922 nuclear receptor binding
GO:0030154 cell differentiation
GO:0042738 exogenous drug catabolic process
GO:0042908 xenobiotic transport
GO:0045111 intermediate filament cytoskeleton
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions