Entity Details

Primary name Pbx1
Entity type gene
Source Source Link

Details

PrimaryID18514
RefseqGene
SymbolPbx1
Namepre B cell leukemia homeobox 1
Chromosome1
Location1 75.95 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPBX1_MOUSE

GO terms

Show/Hide Table
GOName
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001654 eye development
GO:0001655 urogenital system development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001779 natural killer cell differentiation
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006694 steroid biosynthetic process
GO:0007420 brain development
GO:0007548 sex differentiation
GO:0008134 transcription factor binding
GO:0008284 positive regulation of cell population proliferation
GO:0009887 animal organ morphogenesis
GO:0009952 anterior/posterior pattern specification
GO:0009954 proximal/distal pattern formation
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
GO:0030278 regulation of ossification
GO:0030325 adrenal gland development
GO:0030326 embryonic limb morphogenesis
GO:0035162 embryonic hemopoiesis
GO:0042127 regulation of cell population proliferation
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0045665 negative regulation of neuron differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048536 spleen development
GO:0048538 thymus development
GO:0048568 embryonic organ development
GO:0048666 neuron development
GO:0048706 embryonic skeletal system development
GO:0090575 RNA polymerase II transcription regulator complex
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

Show/Hide Table

Interactions

21 interactions

InteractorPartnerSourcesPublicationsLink
Pbx1Hoxa9BioGRID, DIP, IntAct, MINT12923056 15161102 20211142 22745600 details
Pbx1Meis1BioGRID, IntAct, MINT10373562 20211142 9315626 details
Pbx1Hoxb8BioGRID, DIP, IntAct20211142 22745600 details
Pbx1Hoxb6BioGRID, DIP, IntAct20211142 22745600 details
Pbx1Meis2BioGRID, IntAct20211142 details
Pbx1Hoxd4BioGRID, IntAct20211142 details
Pbx1Hoxd10BioGRID, IntAct20211142 details
Pbx1Hoxc5BioGRID, IntAct20211142 details
Pbx1Hoxc4BioGRID, IntAct20211142 details
Pbx1Hoxc12BioGRID, IntAct20211142 details
Pbx1Hoxa6BioGRID, IntAct20211142 details
Pbx1Hoxa5BioGRID, IntAct20211142 details
Pbx1Hoxa10BioGRID, IntAct20211142 details
Pbx1Pknox1BioGRID, IntAct10654609 17623278 20211142 details
Pbx1Pknox2BioGRID, IntAct20211142 details
Pbx1Tcf21BioGRID, IntAct20211142 details
Pbx1Zfp593BioGRID, IntAct20211142 details
Pbx1POU2F1BioGRID15138251 details
Pbx1Smad2BioGRID14764653 details
Pbx1Smad3BioGRID14764653 details
Pbx1Smad4BioGRID14764653 details