Entity Details

Primary name Furin
Entity type gene
Source Source Link

Details

PrimaryID18550
RefseqGene
SymbolFurin
Namefurin (paired basic amino acid cleaving enzyme)
Chromosome7
Location7 45.65 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsFURIN_MOUSE

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001825 blastocyst formation
GO:0002020 protease binding
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005769 early endosome
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0006465 signal peptide processing
GO:0008233 peptidase activity
GO:0009966 regulation of signal transduction
GO:0009986 cell surface
GO:0010008 endosome membrane
GO:0012510 trans-Golgi network transport vesicle membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016485 protein processing
GO:0016486 peptide hormone processing
GO:0019058 viral life cycle
GO:0030140 trans-Golgi network transport vesicle
GO:0030173 integral component of Golgi membrane
GO:0030335 positive regulation of cell migration
GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway
GO:0031638 zymogen activation
GO:0031985 Golgi cisterna
GO:0032374 regulation of cholesterol transport
GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process
GO:0032902 nerve growth factor production
GO:0032911 negative regulation of transforming growth factor beta1 production
GO:0032940 secretion by cell
GO:0042176 regulation of protein catabolic process
GO:0042277 peptide binding
GO:0043043 peptide biosynthetic process
GO:0045121 membrane raft
GO:0046872 metal ion binding
GO:0048406 nerve growth factor binding
GO:0052548 regulation of endopeptidase activity
GO:0090472 dibasic protein processing
GO:0097341 zymogen inhibition
GO:1901394 positive regulation of transforming growth factor beta1 activation

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
FurinCol23a1BioGRID32325033 details
FurinDsg3BioGRID32325033 details
FurinCfdBioGRID30550785 details
FurinFndc5BioGRID30550785 details