Entity Details

Primary name Pdgfrb
Entity type gene
Source Source Link

Details

PrimaryID18596
RefseqGene
SymbolPdgfrb
Nameplatelet derived growth factor receptor, beta polypeptide
Chromosome18
Location18 34.41 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPGFRB_MOUSE

GO terms

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GOName
GO:0001568 blood vessel development
GO:0001701 in utero embryonic development
GO:0001726 ruffle
GO:0001822 kidney development
GO:0001894 tissue homeostasis
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005017 platelet-derived growth factor-activated receptor activity
GO:0005019 platelet-derived growth factor beta-receptor activity
GO:0005102 signaling receptor binding
GO:0005161 platelet-derived growth factor receptor binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006024 glycosaminoglycan biosynthetic process
GO:0006807 nitrogen compound metabolic process
GO:0007165 signal transduction
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0008284 positive regulation of cell population proliferation
GO:0009986 cell surface
GO:0010863 positive regulation of phospholipase C activity
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014911 positive regulation of smooth muscle cell migration
GO:0016020 membrane
GO:0016301 kinase activity
GO:0016324 apical plasma membrane
GO:0016477 cell migration
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0019838 growth factor binding
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0030325 adrenal gland development
GO:0030335 positive regulation of cell migration
GO:0031226 intrinsic component of plasma membrane
GO:0031410 cytoplasmic vesicle
GO:0032516 positive regulation of phosphoprotein phosphatase activity
GO:0032956 regulation of actin cytoskeleton organization
GO:0032967 positive regulation of collagen biosynthetic process
GO:0033674 positive regulation of kinase activity
GO:0035025 positive regulation of Rho protein signal transduction
GO:0035441 cell migration involved in vasculogenesis
GO:0035556 intracellular signal transduction
GO:0035789 metanephric mesenchymal cell migration
GO:0035791 platelet-derived growth factor receptor-beta signaling pathway
GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
GO:0035909 aorta morphogenesis
GO:0038085 vascular endothelial growth factor binding
GO:0038091 positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043202 lysosomal lumen
GO:0043231 intracellular membrane-bounded organelle
GO:0043235 receptor complex
GO:0043406 positive regulation of MAP kinase activity
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0045840 positive regulation of mitotic nuclear division
GO:0046488 phosphatidylinositol metabolic process
GO:0046777 protein autophosphorylation
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048015 phosphatidylinositol-mediated signaling
GO:0048146 positive regulation of fibroblast proliferation
GO:0048407 platelet-derived growth factor binding
GO:0048568 embryonic organ development
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0048705 skeletal system morphogenesis
GO:0048745 smooth muscle tissue development
GO:0050730 regulation of peptidyl-tyrosine phosphorylation
GO:0050921 positive regulation of chemotaxis
GO:0055003 cardiac myofibril assembly
GO:0060326 cell chemotaxis
GO:0060437 lung growth
GO:0060947 cardiac vascular smooth muscle cell differentiation
GO:0060981 cell migration involved in coronary angiogenesis
GO:0061298 retina vasculature development in camera-type eye
GO:0070301 cellular response to hydrogen peroxide
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071670 smooth muscle cell chemotaxis
GO:0072223 metanephric glomerular mesangium development
GO:0072262 metanephric glomerular mesangial cell proliferation involved in metanephros development
GO:0072277 metanephric glomerular capillary formation
GO:0090280 positive regulation of calcium ion import
GO:0097178 ruffle assembly
GO:0106096 response to ceramide
GO:2000379 positive regulation of reactive oxygen species metabolic process
GO:2000491 positive regulation of hepatic stellate cell activation
GO:2000573 positive regulation of DNA biosynthetic process

Diseases

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