Entity Details

Primary name Prkaca
Entity type gene
Source Source Link

Details

PrimaryID18747
RefseqGene
SymbolPrkaca
Nameprotein kinase, cAMP dependent, catalytic, alpha
Chromosome8
Location8
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsKAPCA_MOUSE

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0001669 acrosomal vesicle
GO:0001707 mesoderm formation
GO:0001843 neural tube closure
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004679 AMP-activated protein kinase activity
GO:0004691 cAMP-dependent protein kinase activity
GO:0004712 protein serine/threonine/tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005930 axoneme
GO:0005952 cAMP-dependent protein kinase complex
GO:0006397 mRNA processing
GO:0006468 protein phosphorylation
GO:0008284 positive regulation of cell population proliferation
GO:0010737 protein kinase A signaling
GO:0016020 membrane
GO:0016607 nuclear speck
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0030145 manganese ion binding
GO:0031267 small GTPase binding
GO:0031588 nucleotide-activated protein kinase complex
GO:0031594 neuromuscular junction
GO:0031625 ubiquitin protein ligase binding
GO:0032991 protein-containing complex
GO:0034237 protein kinase A regulatory subunit binding
GO:0034605 cellular response to heat
GO:0036126 sperm flagellum
GO:0043005 neuron projection
GO:0043197 dendritic spine
GO:0043457 regulation of cellular respiration
GO:0044853 plasma membrane raft
GO:0044877 protein-containing complex binding
GO:0045667 regulation of osteoblast differentiation
GO:0046777 protein autophosphorylation
GO:0046827 positive regulation of protein export from nucleus
GO:0048240 sperm capacitation
GO:0048471 perinuclear region of cytoplasm
GO:0048792 spontaneous exocytosis of neurotransmitter
GO:0050804 modulation of chemical synaptic transmission
GO:0051447 negative regulation of meiotic cell cycle
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0061136 regulation of proteasomal protein catabolic process
GO:0070613 regulation of protein processing
GO:0071333 cellular response to glucose stimulus
GO:0071374 cellular response to parathyroid hormone stimulus
GO:0097225 sperm midpiece
GO:0097546 ciliary base
GO:0098793 presynapse
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:2000810 regulation of bicellular tight junction assembly

Diseases

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Interactions

65 interactions

InteractorPartnerSourcesPublicationsLink
PrkacaPde3aMINT17124499 details
PrkacaLrrk2IntAct21390248 details
PrkacaPrkar2bBioGRID, DIP, IntAct21614075 22323819 24464040 26158466 26278174 32325033 details
PrkacaPrkar1aDIP16924114 details
PrkacaERN1DIP21911379 details
PrkacaPkiaBioGRID, DIP, IntAct23458248 26833386 32325033 details
PrkacaPlnIntAct32873725 details
PrkacaPRKAR1AIntAct26405036 details
PrkacaMbpBioGRID22496451 details
PrkacaSrcBioGRID11804588 details
PrkacaSox9BioGRID15889150 details
PrkacaEif4ebp2BioGRID8939971 details
PrkacaLasp1BioGRID15465019 details
PrkacaLASP1BioGRID15465019 details
PrkacaPnpla2BioGRID22733971 details
PrkacaMAPTBioGRID19138662 19647741 details
PrkacaAtp6v1aBioGRID20525692 details
PrkacaMaptBioGRID23362255 30068389 details
PrkacaAdrb1MINT18188154 details
PrkacaDACT1UniProt21262972 details
PrkacaGsk3bbhf-ucl11035810 details
PrkacaGSK3Bbhf-ucl11035810 details
PrkacaGrin2bBioGRID10862698 details
PrkacaBadBioGRID12931191 32325033 details
PrkacaGckBioGRID12931191 details
PrkacaRsbn1BioGRID14724137 details
PrkacaTrpv1BioGRID18463244 details
PrkacaPark7BioGRID31353306 details
PrkacaGrin1BioGRID, MINT10862698 details
PrkacaPpp2r1aIntAct16857963 details
PrkacaTnikBioGRID, IntAct28671696 details
PrkacaAgap2BioGRID, IntAct28706196 details
PrkacaCAMK2DIntAct32873725 details
PrkacaAtxn1BioGRID30457570 details
PrkacaTia1BioGRID27160897 details
PrkacaCamkk2BioGRID32325033 details
PrkacaCdk5rap2BioGRID32325033 details
PrkacaDnajc5BioGRID32325033 details
PrkacaGsk3aBioGRID32325033 details
PrkacaGusbBioGRID32325033 details
PrkacaItpkaBioGRID32325033 details
PrkacaLcp1BioGRID32325033 details
PrkacaPdpk1BioGRID32325033 details
PrkacaNmt1BioGRID32325033 details
PrkacaTaok1BioGRID32325033 details
PrkacaUso1BioGRID32325033 details
PrkacaAdd2BioGRID32325033 details
PrkacaArpc1aBioGRID32325033 details
PrkacaDcaf7BioGRID32325033 details
PrkacaDmtnBioGRID32325033 details
PrkacaDyrk1aBioGRID32325033 details
PrkacaFxyd1BioGRID32325033 details
PrkacaGad2BioGRID32325033 details
PrkacaGna13BioGRID32325033 details
PrkacaGria4BioGRID32325033 details
PrkacaGskipBioGRID32325033 details
PrkacaItpr1BioGRID32325033 details
PrkacaPpp1caBioGRID32325033 details
PrkacaPpp1r17BioGRID32325033 details
PrkacaPpp1r1bBioGRID32325033 details
PrkacaPpp2r5eBioGRID32325033 details
PrkacaRyr2BioGRID32325033 details
PrkacaSlc4a4BioGRID32325033 details
PrkacaPrkar1bBioGRID32325033 details
PrkacaThBioGRID32325033 details