Entity Details

Primary name Prkca
Entity type gene
Source Source Link

Details

PrimaryID18750
RefseqGene
SymbolPrkca
Nameprotein kinase C, alpha
Chromosome11
Location11 70.8 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsKPCA_MOUSE

GO terms

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GOName
GO:0000188 obsolete inactivation of MAPK activity
GO:0000302 response to reactive oxygen species
GO:0001525 angiogenesis
GO:0001750 photoreceptor outer segment
GO:0001933 negative regulation of protein phosphorylation
GO:0001934 positive regulation of protein phosphorylation
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002026 regulation of the force of heart contraction
GO:0002062 chondrocyte differentiation
GO:0002159 desmosome assembly
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004697 protein kinase C activity
GO:0004698 calcium-dependent protein kinase C activity
GO:0005178 integrin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0006469 negative regulation of protein kinase activity
GO:0006874 cellular calcium ion homeostasis
GO:0006937 regulation of muscle contraction
GO:0007155 cell adhesion
GO:0007611 learning or memory
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell population proliferation
GO:0010360 negative regulation of anion channel activity
GO:0010595 positive regulation of endothelial cell migration
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0017148 negative regulation of translation
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019899 enzyme binding
GO:0021955 central nervous system neuron axonogenesis
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0030425 dendrite
GO:0030593 neutrophil chemotaxis
GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0031966 mitochondrial membrane
GO:0032355 response to estradiol
GO:0032991 protein-containing complex
GO:0034351 negative regulation of glial cell apoptotic process
GO:0035403 histone kinase activity (H3-T6 specific)
GO:0035408 histone H3-T6 phosphorylation
GO:0035556 intracellular signal transduction
GO:0035866 alphav-beta3 integrin-PKCalpha complex
GO:0036289 peptidyl-serine autophosphorylation
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0044305 calyx of Held
GO:0045121 membrane raft
GO:0045177 apical part of cell
GO:0045471 response to ethanol
GO:0045651 positive regulation of macrophage differentiation
GO:0045766 positive regulation of angiogenesis
GO:0045780 positive regulation of bone resorption
GO:0045785 positive regulation of cell adhesion
GO:0045822 negative regulation of heart contraction
GO:0045921 positive regulation of exocytosis
GO:0045931 positive regulation of mitotic cell cycle
GO:0046325 negative regulation of glucose import
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0046777 protein autophosphorylation
GO:0047484 regulation of response to osmotic stress
GO:0048259 regulation of receptor-mediated endocytosis
GO:0048471 perinuclear region of cytoplasm
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050729 positive regulation of inflammatory response
GO:0050730 regulation of peptidyl-tyrosine phosphorylation
GO:0050930 induction of positive chemotaxis
GO:0051965 positive regulation of synapse assembly
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0070555 response to interleukin-1
GO:0071322 cellular response to carbohydrate stimulus
GO:0090330 regulation of platelet aggregation
GO:0097193 intrinsic apoptotic signaling pathway
GO:0099171 presynaptic modulation of chemical synaptic transmission
GO:0099523 presynaptic cytosol
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000300 regulation of synaptic vesicle exocytosis
GO:2000707 positive regulation of dense core granule biogenesis

Diseases

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