Entity Details

Primary name Plcg1
Entity type gene
Source Source Link

Details

PrimaryID18803
RefseqGene
SymbolPlcg1
Namephospholipase C, gamma 1
Chromosome2
Location2 80.97 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-25
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPLCG1_MOUSE

GO terms

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GOName
GO:0001701 in utero embryonic development
GO:0001726 ruffle
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0005158 insulin receptor binding
GO:0005168 neurotrophin TRKA receptor binding
GO:0005509 calcium ion binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0006816 calcium ion transport
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0008180 COP9 signalosome
GO:0009306 protein secretion
GO:0009395 phospholipid catabolic process
GO:0010634 positive regulation of epithelial cell migration
GO:0016477 cell migration
GO:0019722 calcium-mediated signaling
GO:0019901 protein kinase binding
GO:0030027 lamellipodium
GO:0030136 clathrin-coated vesicle
GO:0030971 receptor tyrosine kinase binding
GO:0032959 inositol trisphosphate biosynthetic process
GO:0035254 glutamate receptor binding
GO:0042995 cell projection
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0045766 positive regulation of angiogenesis
GO:0046488 phosphatidylinositol metabolic process
GO:0050429 calcium-dependent phospholipase C activity
GO:0050804 modulation of chemical synaptic transmission
GO:0050852 T cell receptor signaling pathway
GO:0051219 phosphoprotein binding
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098978 glutamatergic synapse
GO:1901339 regulation of store-operated calcium channel activity
GO:1905564 positive regulation of vascular endothelial cell proliferation
GO:2000353 positive regulation of endothelial cell apoptotic process

Diseases

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Interactions

53 interactions

InteractorPartnerSourcesPublicationsLink
Plcg1Cd22BioGRID, IntAct10373493 details
Plcg1Gab1MINT10871282 details
Plcg1EporIntAct15953601 details
Plcg1Ranbp2IntAct15102471 details
Plcg1LeprMINT16698021 details
Plcg1RETMINT8662982 details
Plcg1PdgfrbBioGRID17620338 9843497 details
Plcg1Itgb1BioGRID30333137 details
Plcg1Grin2bBioGRID, IntAct10862698 16635246 details
Plcg1Inpp5dIntAct15953601 details
Plcg1Grb2BioGRID, InnateDB, IntAct15953601 22561606 32325033 details
Plcg1Sos1BioGRID, IntAct15953601 32325033 details
Plcg1Flt1BioGRID, MINT17962812 details
Plcg1PTPN1MINT18515860 details
Plcg1VAV1MINT17050525 details
Plcg1KdrMINT11387210 details
Plcg1Vil1UniProt17229814 details
Plcg1Stk11MINT21487392 details
Plcg1LatInnateDB, IntAct, MINT21487392 22561606 24584089 details
Plcg1CblBioGRID, IntAct27474268 32325033 7517397 details
Plcg1Dab1BioGRID15062102 details
Plcg1TecBioGRID10823839 details
Plcg1Ntrk1BioGRID21574998 details
Plcg1Ncam1BioGRID15865439 32325033 details
Plcg1Grin1BioGRID, IntAct, MINT10862698 16635246 details
Plcg1ThemisInnateDB22561606 details
Plcg1Lcp2IntAct24584089 details
Plcg1Pag1IntAct26512138 details
Plcg1Ntrk2BioGRID, DIP23424281 details
Plcg1Cops7aBioGRID32325033 details
Plcg1Cops8BioGRID32325033 details
Plcg1Dpp7BioGRID32325033 details
Plcg1Ehd4BioGRID32325033 details
Plcg1Git1BioGRID32325033 details
Plcg1Nfat5BioGRID32325033 details
Plcg1Cops2BioGRID32325033 details
Plcg1Cops4BioGRID32325033 details
Plcg1Pik3r1BioGRID32325033 details
Plcg1Serpinc1BioGRID32325033 details
Plcg1TubBioGRID32325033 details
Plcg1PygbBioGRID32325033 details
Plcg1Nck1BioGRID32325033 details
Plcg1Cops3BioGRID32325033 details
Plcg1Cops6BioGRID32325033 details
Plcg1CtssBioGRID32325033 details
Plcg1Dynll1BioGRID32325033 details
Plcg1Hsp90ab1BioGRID32325033 details
Plcg1Hspa5BioGRID32325033 details
Plcg1PitpnaBioGRID32325033 details
Plcg1Ptpn11BioGRID32325033 details
Plcg1Rgs7BioGRID32325033 details
Plcg1Snap91BioGRID32325033 details
Plcg1SrcBioGRID32325033 details