Entity Details

Primary name Plk1
Entity type gene
Source Source Link

Details

PrimaryID18817
RefseqGene
SymbolPlk1
Namepolo like kinase 1
Chromosome7
Location7 65.52 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPLK1_MOUSE

GO terms

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GOName
GO:0000070 mitotic sister chromatid segregation
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000132 establishment of mitotic spindle orientation
GO:0000278 mitotic cell cycle
GO:0000281 mitotic cytokinesis
GO:0000287 magnesium ion binding
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000779 condensed chromosome, centromeric region
GO:0000785 chromatin
GO:0000795 synaptonemal complex
GO:0000922 spindle pole
GO:0001578 microtubule bundle formation
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005819 spindle
GO:0005876 spindle microtubule
GO:0006468 protein phosphorylation
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0007098 centrosome cycle
GO:0007346 regulation of mitotic cell cycle
GO:0008017 microtubule binding
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0010997 anaphase-promoting complex binding
GO:0015630 microtubule cytoskeleton
GO:0016321 female meiosis chromosome segregation
GO:0016567 protein ubiquitination
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0030071 regulation of mitotic metaphase/anaphase transition
GO:0030496 midbody
GO:0031648 protein destabilization
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032465 regulation of cytokinesis
GO:0033365 protein localization to organelle
GO:0034451 centriolar satellite
GO:0040038 polar body extrusion after meiotic divisions
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043393 regulation of protein binding
GO:0045143 homologous chromosome segregation
GO:0045184 establishment of protein localization
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045862 positive regulation of proteolysis
GO:0051081 nuclear membrane disassembly
GO:0051233 spindle midzone
GO:0051443 positive regulation of ubiquitin-protein transferase activity
GO:0070194 synaptonemal complex disassembly
GO:0071168 protein localization to chromatin
GO:0090435 protein localization to nuclear envelope
GO:0097431 mitotic spindle pole
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901673 regulation of mitotic spindle assembly
GO:1904668 positive regulation of ubiquitin protein ligase activity
GO:1904776 regulation of protein localization to cell cortex

Diseases

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Interactions

41 interactions

InteractorPartnerSourcesPublicationsLink
Plk1MeikinDIP25533956 details
Plk1Ddx39bBioGRID21637952 details
Plk1KitBioGRID10679268 details
Plk1SREBF1BioGRID27579997 details
Plk1OTUD4BioGRID31138677 details
Plk1Nek9MINT21642957 details
Plk1Axin2DIP16815967 details
Plk1AXIN2DIP16815967 details
Plk1BICD2BioGRID, IntAct20360068 details
Plk1PLK1BioGRID, IntAct20360068 details
Plk1NSUN2BioGRID, IntAct20360068 details
Plk1TRIOBPBioGRID, IntAct20360068 details
Plk1RANGAP1BioGRID, IntAct20360068 details
Plk1CEP97BioGRID, IntAct20360068 details
Plk1STXBP4BioGRID, IntAct20360068 details
Plk1SPAG5BioGRID, IntAct20360068 details
Plk1PRRC1BioGRID, IntAct20360068 details
Plk1RANBP2BioGRID, IntAct20360068 details
Plk1TOPBP1BioGRID, IntAct20360068 details
Plk1RAI14BioGRID, IntAct20360068 details
Plk1NUP214BioGRID, IntAct20360068 details
Plk1KIF24BioGRID, IntAct20360068 details
Plk1SUMO1BioGRID, IntAct20360068 details
Plk1HAUS5IntAct20360068 details
Plk1ERCC6LBioGRID, IntAct20360068 details
Plk1KNSTRNBioGRID, IntAct20360068 details
Plk1WDCPBioGRID, IntAct20360068 details
Plk1HAUS8BioGRID, IntAct20360068 details
Plk1BORABioGRID, IntAct20360068 details
Plk1SPAG9BioGRID, IntAct20360068 details
Plk1SLX4BioGRID, IntAct20360068 details
Plk1HAUS1BioGRID, IntAct20360068 details
Plk1RGPD8BioGRID, IntAct20360068 details
Plk1Hmga2IntAct26045162 details
Plk1PRC1BioGRID20360068 details
Plk1Pou5f1BioGRID22083510 details
Plk1Foxp3BioGRID22922362 details
Plk1Wdtc1BioGRID27113764 details
Plk1Senp7BioGRID31825833 details
Plk1Srsf1IntAct23663783 details
Plk1Srsf2IntAct23663783 details