Entity Details

Primary name Pparg
Entity type gene
Source Source Link

Details

PrimaryID19016
RefseqGene
SymbolPparg
Nameperoxisome proliferator activated receptor gamma
Chromosome6
Location6 53.41 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-08-11
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPPARG_MOUSE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001818 negative regulation of cytokine production
GO:0001890 placenta development
GO:0002021 response to dietary excess
GO:0002024 diet induced thermogenesis
GO:0002674 negative regulation of acute inflammatory response
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006631 fatty acid metabolic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0008217 regulation of blood pressure
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell population proliferation
GO:0009416 response to light stimulus
GO:0009755 hormone-mediated signaling pathway
GO:0010468 regulation of gene expression
GO:0010742 macrophage derived foam cell differentiation
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010887 negative regulation of cholesterol storage
GO:0010891 negative regulation of sequestering of triglyceride
GO:0015909 long-chain fatty acid transport
GO:0016525 negative regulation of angiogenesis
GO:0019216 regulation of lipid metabolic process
GO:0019395 fatty acid oxidation
GO:0019899 enzyme binding
GO:0019903 protein phosphatase binding
GO:0030154 cell differentiation
GO:0030224 monocyte differentiation
GO:0030308 negative regulation of cell growth
GO:0030331 estrogen receptor binding
GO:0030374 nuclear receptor coactivator activity
GO:0030514 negative regulation of BMP signaling pathway
GO:0030855 epithelial cell differentiation
GO:0032094 response to food
GO:0032869 cellular response to insulin stimulus
GO:0032966 negative regulation of collagen biosynthetic process
GO:0033993 response to lipid
GO:0035357 peroxisome proliferator activated receptor signaling pathway
GO:0042277 peptide binding
GO:0042593 glucose homeostasis
GO:0042752 regulation of circadian rhythm
GO:0042802 identical protein binding
GO:0042953 lipoprotein transport
GO:0043065 positive regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043235 receptor complex
GO:0043388 positive regulation of DNA binding
GO:0043537 negative regulation of blood vessel endothelial cell migration
GO:0043621 protein self-association
GO:0045165 cell fate commitment
GO:0045444 fat cell differentiation
GO:0045598 regulation of fat cell differentiation
GO:0045600 positive regulation of fat cell differentiation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045923 positive regulation of fatty acid metabolic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046321 positive regulation of fatty acid oxidation
GO:0046965 retinoid X receptor binding
GO:0048384 retinoic acid receptor signaling pathway
GO:0048469 cell maturation
GO:0048471 perinuclear region of cytoplasm
GO:0048511 rhythmic process
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0048714 positive regulation of oligodendrocyte differentiation
GO:0050544 arachidonic acid binding
GO:0050692 DNA binding domain binding
GO:0050693 LBD domain binding
GO:0050699 WW domain binding
GO:0050728 negative regulation of inflammatory response
GO:0050872 white fat cell differentiation
GO:0050873 brown fat cell differentiation
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051393 alpha-actinin binding
GO:0051974 negative regulation of telomerase activity
GO:0060100 positive regulation of phagocytosis, engulfment
GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway
GO:0060965 negative regulation of gene silencing by miRNA
GO:0070888 E-box binding
GO:0071285 cellular response to lithium ion
GO:0071404 cellular response to low-density lipoprotein particle stimulus
GO:0071407 cellular response to organic cyclic compound
GO:0090278 negative regulation of peptide hormone secretion
GO:0090575 RNA polymerase II transcription regulator complex
GO:0150079 negative regulation of neuroinflammatory response
GO:1900077 negative regulation of cellular response to insulin stimulus
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1903979 negative regulation of microglial cell activation
GO:1904179 positive regulation of adipose tissue development
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
GO:1905461 positive regulation of vascular associated smooth muscle cell apoptotic process
GO:1905563 negative regulation of vascular endothelial cell proliferation
GO:1905599 positive regulation of low-density lipoprotein receptor activity
GO:1990841 promoter-specific chromatin binding
GO:2000230 negative regulation of pancreatic stellate cell proliferation
GO:2000272 negative regulation of signaling receptor activity

Diseases

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Interactions

78 interactions

InteractorPartnerSourcesPublicationsLink
PpargSIRT1IntAct22863012 details
PpargMED1BioGRID, UniProt12037571 9653119 details
PpargRXRABioGRID10517671 details
PpargMen1BioGRID19596783 details
PpargNCOR2BioGRID16219912 details
PpargTGFB1I1BioGRID15687259 details
PpargNFE2L2BioGRID10930400 details
PpargSp1BioGRID11777901 details
PpargNcoa2BioGRID22664386 details
PpargPias2BioGRID15123625 details
PpargNCOR1BioGRID11903058 details
PpargRxraBioGRID22573555 details
PpargFbxo9BioGRID27197753 details
PpargSirt1BioGRID, IntAct, UniProt15175761 22863012 details
PpargPrdm16IntAct22863012 details
PpargNoctDIP20498072 details
PpargFoxp3DIP22722857 details
PpargIrf6IntAct28526834 details
PpargTACC1IntAct20078863 details
PpargGADD45ABioGRID10872826 details
PpargHdac1BioGRID16431920 details
PpargSiah2BioGRID22294748 details
PpargHSP90AA1BioGRID12962497 details
PpargBCL6BioGRID12970571 details
PpargRelaBioGRID23250430 details
PpargCav1BioGRID15164767 details
PpargTgif1BioGRID16428452 details
PpargMed14BioGRID20194623 details
PpargPpargc1aBioGRID15687259 25368164 details
PpargTgfb1i1BioGRID15687259 details
PpargUsp7BioGRID24072712 details
PpargVimBioGRID23297177 details
PpargDesBioGRID23297177 details
PpargPpm1bBioGRID23320500 details
PpargAbl1BioGRID25368164 details
PpargSNX19BioGRID27197753 details
PpargPLD2BioGRID27197753 details
PpargTRADDBioGRID27197753 details
PpargADAM22BioGRID27197753 details
PpargITPABioGRID27197753 details
PpargFBXO9BioGRID27197753 details
PpargPDYNBioGRID27197753 details
PpargTNFSF11BioGRID27197753 details
PpargACTBBioGRID27197753 details
PpargMAP3K7BioGRID27197753 details
PpargZC3H3BioGRID27197753 details
PpargACTBL2BioGRID27197753 details
PpargACTG1BioGRID27197753 details
PpargZRANB3BioGRID27197753 details
PpargPKD1L3BioGRID27197753 details
PpargDUOX1BioGRID27197753 details
PpargRTCBBioGRID27197753 details
PpargTRIOBPBioGRID27197753 details
PpargLAMC2BioGRID27197753 details
PpargMLH1BioGRID27197753 details
PpargHTR3DBioGRID27197753 details
PpargABCA5BioGRID27197753 details
PpargPPARGBioGRID27197753 details
PpargAP3D1BioGRID27197753 details
PpargHECTD2BioGRID27197753 details
PpargTRPV6BioGRID27197753 details
PpargDCST1BioGRID27197753 details
PpargTOPBP1BioGRID27197753 details
PpargITGA8BioGRID27197753 details
PpargAIFM3BioGRID27197753 details
PpargTTNBioGRID27197753 details
PpargZNF404BioGRID27197753 details
PpargKIF18BBioGRID27197753 details
PpargTIGD1BioGRID27197753 details
PpargGARNL3BioGRID27197753 details
PpargCOPRSBioGRID27197753 details
PpargHAS1BioGRID27197753 details
PpargSCAPERBioGRID27197753 details
PpargITGA9BioGRID27197753 details
PpargCHD1BioGRID27197753 details
PpargNedd4BioGRID27917940 details
PpargWwtr1BioGRID16099986 details
PpargSmurf1BioGRID30566427 details