Entity Details

Primary name Ppp3ca
Entity type gene
Source Source Link

Details

PrimaryID19055
RefseqGene
SymbolPpp3ca
Nameprotein phosphatase 3, catalytic subunit, alpha isoform
Chromosome3
Location3
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-25
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPP2BA_MOUSE

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0001975 response to amphetamine
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0004723 calcium-dependent protein serine/threonine phosphatase activity
GO:0005516 calmodulin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005955 calcineurin complex
GO:0006470 protein dephosphorylation
GO:0006606 protein import into nucleus
GO:0006816 calcium ion transport
GO:0007420 brain development
GO:0007568 aging
GO:0009898 cytoplasmic side of plasma membrane
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0014883 transition between fast and slow fiber
GO:0014898 cardiac muscle hypertrophy in response to stress
GO:0016018 cyclosporin A binding
GO:0016311 dephosphorylation
GO:0019722 calcium-mediated signaling
GO:0019899 enzyme binding
GO:0030018 Z disc
GO:0030335 positive regulation of cell migration
GO:0033173 calcineurin-NFAT signaling cascade
GO:0033192 calmodulin-dependent protein phosphatase activity
GO:0033555 multicellular organismal response to stress
GO:0035562 negative regulation of chromatin binding
GO:0036057 slit diaphragm
GO:0042383 sarcolemma
GO:0043197 dendritic spine
GO:0044877 protein-containing complex binding
GO:0045202 synapse
GO:0045785 positive regulation of cell adhesion
GO:0045807 positive regulation of endocytosis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046676 negative regulation of insulin secretion
GO:0046872 metal ion binding
GO:0046983 protein dimerization activity
GO:0048741 skeletal muscle fiber development
GO:0050774 negative regulation of dendrite morphogenesis
GO:0050804 modulation of chemical synaptic transmission
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051117 ATPase binding
GO:0051592 response to calcium ion
GO:0060079 excitatory postsynaptic potential
GO:0070262 peptidyl-serine dephosphorylation
GO:0071333 cellular response to glucose stimulus
GO:0097720 calcineurin-mediated signaling
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098978 glutamatergic synapse
GO:0099170 postsynaptic modulation of chemical synaptic transmission
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:1903244 positive regulation of cardiac muscle hypertrophy in response to stress
GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA
GO:1905205 positive regulation of connective tissue replacement

Diseases

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Interactions

45 interactions

InteractorPartnerSourcesPublicationsLink
Ppp3caMTNR1BBioGRID, IntAct26514267 details
Ppp3caGabrg2BioGRID12574411 details
Ppp3caFkbp5BioGRID11813252 details
Ppp3caCrtc2DIP22495310 details
Ppp3caBcl2BioGRID12617961 details
Ppp3caGabrb2BioGRID12574411 details
Ppp3caGabra1BioGRID12574411 details
Ppp3caPatjBioGRID19138174 details
Ppp3caSLC6A4BioGRID24107951 details
Ppp3caGrin1BioGRID, IntAct, MINT10862698 16635246 details
Ppp3caGrin2bBioGRID, IntAct, MINT10862698 16635246 details
Ppp3caYwhabIntAct16635246 details
Ppp3caCALM1BioGRID, IntAct16512683 details
Ppp3caCALM2IntAct16512683 details
Ppp3caCALM3IntAct16512683 details
Ppp3caYwhazBioGRID, IntAct16959763 19562802 details
Ppp3caDlg4BioGRID, IntAct19455133 27507650 28671696 details
Ppp3caNeurl1aIntAct22153079 details
Ppp3caHomer1BioGRID, IntAct28671696 details
Ppp3caTsc1BioGRID, IntAct28671696 details
Ppp3caDlgap1BioGRID, IntAct27507650 28671696 details
Ppp3caShank3BioGRID, IntAct27507650 28671696 details
Ppp3caAgap2BioGRID, IntAct28706196 details
Ppp3caLnx1BioGRID27889896 details
Ppp3caLnx2BioGRID27889896 details
Ppp3caPpp1r9bBioGRID30562941 details
Ppp3caMaptBioGRID30068389 details
Ppp3caCep76BioGRID32325033 details
Ppp3caHspa12aBioGRID32325033 details
Ppp3caKcnip3BioGRID32325033 details
Ppp3caNrd1BioGRID32325033 details
Ppp3caPpp3ccBioGRID32325033 details
Ppp3caTbc1d17BioGRID32325033 details
Ppp3caMat2bBioGRID32325033 details
Ppp3caNaspBioGRID32325033 details
Ppp3caPfdn5BioGRID32325033 details
Ppp3caPpp2r2aBioGRID32325033 details
Ppp3caItpr1BioGRID32325033 details
Ppp3caPpp3cbBioGRID32325033 details
Ppp3caPtenBioGRID32325033 details
Ppp3caSult4a1BioGRID32325033 details
Ppp3caPpp3r1BioGRID32325033 details
Ppp3caRcan1BioGRID32325033 details
Ppp3caRcan2BioGRID32325033 details
Ppp3caTsnBioGRID32325033 details