Entity Details

Primary name Ptgis
Entity type gene
Source Source Link

Details

PrimaryID19223
RefseqGene
SymbolPtgis
Nameprostaglandin I2 (prostacyclin) synthase
Chromosome2
Location2
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsPTGIS_MOUSE

GO terms

Show/Hide Table
GOName
GO:0001516 prostaglandin biosynthetic process
GO:0001666 response to hypoxia
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005901 caveola
GO:0006690 icosanoid metabolic process
GO:0007566 embryo implantation
GO:0008116 prostaglandin-I synthase activity
GO:0016021 integral component of membrane
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0045766 positive regulation of angiogenesis
GO:0046697 decidualization
GO:0050728 negative regulation of inflammatory response
GO:0071347 cellular response to interleukin-1
GO:0071354 cellular response to interleukin-6
GO:0071456 cellular response to hypoxia
GO:0097190 apoptotic signaling pathway
GO:0106256 hydroperoxy icosatetraenoate dehydratase activity
GO:1900119 positive regulation of execution phase of apoptosis

Diseases

Show/Hide Table

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PtgisFancd2BioGRID28378742 details