Entity Details

Primary name Rac1
Entity type gene
Source Source Link

Details

PrimaryID19353
RefseqGene
SymbolRac1
NameRac family small GTPase 1
Chromosome5
Location5 82.22 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-19
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsRAC1_MOUSE

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000242 pericentriolar material
GO:0001764 neuron migration
GO:0001891 phagocytic cup
GO:0001934 positive regulation of protein phosphorylation
GO:0002093 auditory receptor cell morphogenesis
GO:0002551 mast cell chemotaxis
GO:0003376 sphingosine-1-phosphate receptor signaling pathway
GO:0003382 epithelial cell morphogenesis
GO:0003924 GTPase activity
GO:0003925 G protein activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005802 trans-Golgi network
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0006897 endocytosis
GO:0006911 phagocytosis, engulfment
GO:0006935 chemotaxis
GO:0006972 hyperosmotic response
GO:0007010 cytoskeleton organization
GO:0007015 actin filament organization
GO:0007155 cell adhesion
GO:0007163 establishment or maintenance of cell polarity
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0007411 axon guidance
GO:0008045 motor neuron axon guidance
GO:0008283 cell population proliferation
GO:0008360 regulation of cell shape
GO:0008361 regulation of cell size
GO:0010591 regulation of lamellipodium assembly
GO:0010592 positive regulation of lamellipodium assembly
GO:0010595 positive regulation of endothelial cell migration
GO:0010762 regulation of fibroblast migration
GO:0010764 negative regulation of fibroblast migration
GO:0010811 positive regulation of cell-substrate adhesion
GO:0014041 regulation of neuron maturation
GO:0016020 membrane
GO:0016358 dendrite development
GO:0016477 cell migration
GO:0016601 Rac protein signal transduction
GO:0019897 extrinsic component of plasma membrane
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0021799 cerebral cortex radially oriented cell migration
GO:0021831 embryonic olfactory bulb interneuron precursor migration
GO:0021894 cerebral cortex GABAergic interneuron development
GO:0022604 regulation of cell morphogenesis
GO:0030027 lamellipodium
GO:0030031 cell projection assembly
GO:0030032 lamellipodium assembly
GO:0030036 actin cytoskeleton organization
GO:0030041 actin filament polymerization
GO:0030334 regulation of cell migration
GO:0030742 GTP-dependent protein binding
GO:0030838 positive regulation of actin filament polymerization
GO:0030865 cortical cytoskeleton organization
GO:0030900 forebrain development
GO:0031116 positive regulation of microtubule polymerization
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031267 small GTPase binding
GO:0031410 cytoplasmic vesicle
GO:0031529 ruffle organization
GO:0031901 early endosome membrane
GO:0031996 thioesterase binding
GO:0032587 ruffle membrane
GO:0032707 negative regulation of interleukin-23 production
GO:0032956 regulation of actin cytoskeleton organization
GO:0034446 substrate adhesion-dependent cell spreading
GO:0035567 non-canonical Wnt signaling pathway
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0042470 melanosome
GO:0042826 histone deacetylase binding
GO:0042995 cell projection
GO:0043197 dendritic spine
GO:0043231 intracellular membrane-bounded organelle
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity
GO:0043652 engulfment of apoptotic cell
GO:0044877 protein-containing complex binding
GO:0045216 cell-cell junction organization
GO:0045428 regulation of nitric oxide biosynthetic process
GO:0045453 bone resorption
GO:0045740 positive regulation of DNA replication
GO:0046425 regulation of receptor signaling pathway via JAK-STAT
GO:0048012 hepatocyte growth factor receptor signaling pathway
GO:0048168 regulation of neuronal synaptic plasticity
GO:0048532 anatomical structure arrangement
GO:0048812 neuron projection morphogenesis
GO:0048813 dendrite morphogenesis
GO:0048870 cell motility
GO:0048873 homeostasis of number of cells within a tissue
GO:0051022 Rho GDP-dissociation inhibitor binding
GO:0051117 ATPase binding
GO:0051492 regulation of stress fiber assembly
GO:0051496 positive regulation of stress fiber assembly
GO:0051668 localization within membrane
GO:0051894 positive regulation of focal adhesion assembly
GO:0051932 synaptic transmission, GABAergic
GO:0055038 recycling endosome membrane
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0060091 kinocilium
GO:0060263 regulation of respiratory burst
GO:0060999 positive regulation of dendritic spine development
GO:0061344 regulation of cell adhesion involved in heart morphogenesis
GO:0071260 cellular response to mechanical stimulus
GO:0071526 semaphorin-plexin signaling pathway
GO:0071542 dopaminergic neuron differentiation
GO:0072659 protein localization to plasma membrane
GO:0090023 positive regulation of neutrophil chemotaxis
GO:0090103 cochlea morphogenesis
GO:0097178 ruffle assembly
GO:0098794 postsynapse
GO:0098978 glutamatergic synapse
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1902622 regulation of neutrophil migration
GO:1904948 midbrain dopaminergic neuron differentiation
GO:2000386 positive regulation of ovarian follicle development

Diseases

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Interactions

90 interactions

InteractorPartnerSourcesPublicationsLink
Rac1Cdc42BioGRID, IntAct15102471 32325033 details
Rac1RhoaBioGRID, IntAct15102471 32325033 details
Rac1NonoIntAct15102471 details
Rac1Epb41l2IntAct15102471 details
Rac1Ltbp1IntAct15102471 details
Rac1Rbm39BioGRID, IntAct15102471 32325033 details
Rac1Pik3cbIntAct23706742 details
Rac1Arhgap32BioGRID12531901 32325033 details
Rac1Arhgap1BioGRID14966113 32325033 details
Rac1Arhgap22BioGRID14966113 details
Rac1RCC2BioGRID25074804 details
Rac1AGAP2BioGRID22453919 details
Rac1Traf6BioGRID29114077 details
Rac1UbcBioGRID29676259 details
Rac1Grin2bBioGRID, IntAct10862698 16635246 details
Rac1Cav1MINT17658519 details
Rac1PAK1IntAct, MINT18325335 18854161 19893577 details
Rac1Chn2MINT19306875 details
Rac1Dlg4BioGRID, IntAct19455133 27507650 28671696 details
Rac1Smurf2BioGRID, IntAct19379695 details
Rac1XiapMINT22117219 details
Rac1ARHGDIAMINT22157745 details
Rac1Sod1BioGRID, UniProt18219391 32325033 details
Rac1HACD3BioGRID10747961 details
Rac1Homer2BioGRID10493740 details
Rac1CitBioGRID10493740 details
Rac1Akip1BioGRID17227220 details
Rac1AbrBioGRID17116687 details
Rac1BcrBioGRID17116687 details
Rac1Rcc2BioGRID25074804 32325033 details
Rac1ArhgdiaBioGRID25074804 details
Rac1Dock1BioGRID21289086 details
Rac1Sigmar1BioGRID31149635 details
Rac1MavsBioGRID31149635 details
Rac1TraddBioGRID31149635 details
Rac1Lrrk2BioGRID25926623 details
Rac1Grin1BioGRID, IntAct, MINT10862698 16635246 details
Rac1Ctnnb1IntAct18423204 details
Rac1Mapk9IntAct18423204 details
Rac1Mapk8IntAct18423204 details
Rac1Aplp2IntAct17934213 details
Rac1CybbUniProt18219391 details
Rac1LRRK2IntAct24687852 details
Rac1HTTIntAct17500595 details
Rac1Cyfip1BioGRID, IntAct28671696 32325033 details
Rac1Nckap1BioGRID, IntAct28671696 32325033 details
Rac1TnikBioGRID, IntAct28671696 details
Rac1Tsc1BioGRID, IntAct28671696 details
Rac1Dlgap1BioGRID, IntAct27507650 28671696 details
Rac1Shank3BioGRID, IntAct27507650 28671696 details
Rac1SMURF2BioGRID15761153 details
Rac1EedBioGRID24457600 details
Rac1Fancd2BioGRID28378742 details
Rac1HnrnpkBioGRID26336360 details
Rac1Ppp1r9bBioGRID30562941 details
Rac1Atxn1BioGRID30457570 details
Rac1Ago3BioGRID32325033 details
Rac1Eif4eBioGRID32325033 details
Rac1Ophn1BioGRID32325033 details
Rac1Pak2BioGRID32325033 details
Rac1NclBioGRID32325033 details
Rac1Rpl6BioGRID32325033 details
Rac1Tuba1aBioGRID32325033 details
Rac1Tubb5BioGRID32325033 details
Rac1Arfip2BioGRID32325033 details
Rac1Arhgap44BioGRID32325033 details
Rac1Brk1BioGRID32325033 details
Rac1Cfap36BioGRID32325033 details
Rac1Iqgap1BioGRID32325033 details
Rac1OcrlBioGRID32325033 details
Rac1Pak3BioGRID32325033 details
Rac1Abi2BioGRID32325033 details
Rac1ActbBioGRID32325033 details
Rac1Dhx9BioGRID32325033 details
Rac1Dync1i1BioGRID32325033 details
Rac1Metap2BioGRID32325033 details
Rac1Pabpc1BioGRID32325033 details
Rac1Pcbp1BioGRID32325033 details
Rac1Pip4k2aBioGRID32325033 details
Rac1Pip5k1cBioGRID32325033 details
Rac1Psmc2BioGRID32325033 details
Rac1RhobBioGRID32325033 details
Rac1Rps4xBioGRID32325033 details
Rac1Rps6BioGRID32325033 details
Rac1Rock2BioGRID32325033 details
Rac1SarnpBioGRID32325033 details
Rac1Stau1BioGRID32325033 details
Rac1Wasf1BioGRID32325033 details
Rac1CfdBioGRID30550785 details
Rac1Fndc5BioGRID30550785 details