Entity Details

Primary name Rb1
Entity type gene
Source Source Link

Details

PrimaryID19645
RefseqGene
SymbolRb1
NameRB transcriptional corepressor 1
Chromosome14
Location14 38.73 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-24
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsRB_MOUSE

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0001558 regulation of cell growth
GO:0001894 tissue homeostasis
GO:0003180 aortic valve morphogenesis
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005819 spindle
GO:0006325 chromatin organization
GO:0006469 negative regulation of protein kinase activity
GO:0007265 Ras protein signal transduction
GO:0007346 regulation of mitotic cell cycle
GO:0008024 cyclin/CDK positive transcription elongation factor complex
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0010629 negative regulation of gene expression
GO:0016605 PML body
GO:0019899 enzyme binding
GO:0019900 kinase binding
GO:0030154 cell differentiation
GO:0030182 neuron differentiation
GO:0030308 negative regulation of cell growth
GO:0031134 sister chromatid biorientation
GO:0031175 neuron projection development
GO:0031625 ubiquitin protein ligase binding
GO:0034088 maintenance of mitotic sister chromatid cohesion
GO:0034349 glial cell apoptotic process
GO:0035189 Rb-E2F complex
GO:0035914 skeletal muscle cell differentiation
GO:0042551 neuron maturation
GO:0042802 identical protein binding
GO:0043353 enucleate erythrocyte differentiation
GO:0043550 regulation of lipid kinase activity
GO:0045445 myoblast differentiation
GO:0045651 positive regulation of macrophage differentiation
GO:0045786 negative regulation of cell cycle
GO:0045842 positive regulation of mitotic metaphase/anaphase transition
GO:0045879 negative regulation of smoothened signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045930 negative regulation of mitotic cell cycle
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048565 digestive tract development
GO:0048667 cell morphogenesis involved in neuron differentiation
GO:0050680 negative regulation of epithelial cell proliferation
GO:0050728 negative regulation of inflammatory response
GO:0051146 striated muscle cell differentiation
GO:0051219 phosphoprotein binding
GO:0051301 cell division
GO:0051402 neuron apoptotic process
GO:0051726 regulation of cell cycle
GO:0061676 importin-alpha family protein binding
GO:0071459 protein localization to chromosome, centromeric region
GO:0071466 cellular response to xenobiotic stimulus
GO:0071901 negative regulation of protein serine/threonine kinase activity
GO:0071922 regulation of cohesin loading
GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0097284 hepatocyte apoptotic process
GO:0097718 disordered domain specific binding
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1902948 negative regulation of tau-protein kinase activity
GO:1903055 positive regulation of extracellular matrix organization
GO:1903944 negative regulation of hepatocyte apoptotic process
GO:1904028 positive regulation of collagen fibril organization
GO:1904761 negative regulation of myofibroblast differentiation
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle
GO:2000679 positive regulation of transcription regulatory region DNA binding
GO:2001234 negative regulation of apoptotic signaling pathway

Diseases

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Interactions

71 interactions

InteractorPartnerSourcesPublicationsLink
Rb1Hmgb1MINT11748221 details
Rb1Ppp1ccBioGRID, IntAct17274640 details
Rb1Pax3IntAct9464541 details
Rb1Vsx2IntAct9464541 details
Rb1Smarca4BioGRID, IntAct7923370 details
Rb1Ifi202bUniProt7890747 details
Rb1Ccnd1BioGRID, IntAct15084261 9191053 details
Rb1Runx2BioGRID20211142 details
Rb1CebpdBioGRID20211142 8946919 details
Rb1Id2BioGRID20211142 details
Rb1Kmt5cBioGRID15750587 details
Rb1Kmt5bBioGRID15750587 details
Rb1Cdk2BioGRID16102793 18356301 details
Rb1Cdk4BioGRID11254678 15158336 8547220 details
Rb1E2f1BioGRID12799438 28559429 30109252 details
Rb1CSNK2A1BioGRID21652635 details
Rb1Cdk9BioGRID9827693 details
Rb1RbakBioGRID10702291 details
Rb1Cdk6BioGRID11254678 details
Rb1CebpaBioGRID8946919 details
Rb1CebpbBioGRID8946919 details
Rb1CDK2BioGRID9840932 details
Rb1CDK4BioGRID9840932 details
Rb1Ifi211MINT16458891 details
Rb1Ifi204MINT16458891 details
Rb1DgkzIntAct16286473 details
Rb1Hmga2BioGRID, IntAct16766265 32325033 details
Rb1Ppp1caIntAct17274640 details
Rb1Ppp1cbIntAct17274640 details
Rb1Pdx1MINT21399612 details
Rb1CcncIntAct15084261 details
Rb1Ccnd3IntAct15084261 details
Rb1GATA1BioGRID, DIP19513100 details
Rb1Gata1DIP19513100 details
Rb1E2f3DIP20016602 details
Rb1Hdac1BioGRID10409740 11684023 details
Rb1ZFPM1BioGRID19513100 details
Rb1Psmd10BioGRID17292836 30109252 details
Rb1Neurod1BioGRID15701640 details
Rb1Morf4l1BioGRID15367658 details
Rb1Mrfap1BioGRID15367658 details
Rb1Jarid2BioGRID15870077 details
Rb1Pax2BioGRID12200151 details
Rb1PrkcbBioGRID11805327 details
Rb1E2f4IntAct20946988 details
Rb1CDKN1BIntAct21423803 details
Rb1E2f2BioGRID, DIP19513100 details
Rb1Ttc23BioGRID29459677 details
Rb1Abt1BioGRID32325033 details
Rb1AjubaBioGRID32325033 details
Rb1ArntBioGRID32325033 details
Rb1Deaf1BioGRID32325033 details
Rb1Epas1BioGRID32325033 details
Rb1NfixBioGRID32325033 details
Rb1Nr4a3BioGRID32325033 details
Rb1Pax8BioGRID32325033 details
Rb1RargBioGRID32325033 details
Rb1ClockBioGRID32325033 details
Rb1Ep300BioGRID32325033 details
Rb1FosBioGRID32325033 details
Rb1Ldb2BioGRID32325033 details
Rb1MgaBioGRID32325033 details
Rb1RbpjlBioGRID32325033 details
Rb1Rbl1BioGRID32325033 details
Rb1Rbl2BioGRID32325033 details
Rb1Rcor2BioGRID32325033 details
Rb1Smyd2BioGRID32325033 details
Rb1Snapc1BioGRID32325033 details
Rb1Tfdp1BioGRID32325033 details
Rb1Wwtr1BioGRID32325033 details
Rb1Yap1BioGRID32325033 details