Entity Details

Primary name Sin3a
Entity type gene
Source Source Link

Details

PrimaryID20466
RefseqGene
SymbolSin3a
Nametranscriptional regulator, SIN3A (yeast)
Chromosome9
Location9 30.89 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-05-26
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSIN3A_MOUSE

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000776 kinetochore
GO:0000785 chromatin
GO:0001701 in utero embryonic development
GO:0002218 activation of innate immune response
GO:0002230 positive regulation of defense response to virus by host
GO:0002244 hematopoietic progenitor cell differentiation
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005730 nucleolus
GO:0006260 DNA replication
GO:0006355 regulation of transcription, DNA-templated
GO:0006476 protein deacetylation
GO:0007568 aging
GO:0008134 transcription factor binding
GO:0010243 response to organonitrogen compound
GO:0010817 regulation of hormone levels
GO:0010971 positive regulation of G2/M transition of mitotic cell cycle
GO:0016575 histone deacetylation
GO:0016580 Sin3 complex
GO:0017053 transcription repressor complex
GO:0021895 cerebral cortex neuron differentiation
GO:0030516 regulation of axon extension
GO:0031937 positive regulation of chromatin silencing
GO:0032991 protein-containing complex
GO:0034613 cellular protein localization
GO:0042754 negative regulation of circadian rhythm
GO:0043066 negative regulation of apoptotic process
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0044877 protein-containing complex binding
GO:0045666 positive regulation of neuron differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048511 rhythmic process
GO:0051595 response to methylglyoxal
GO:0071333 cellular response to glucose stimulus
GO:0140416 transcription regulator inhibitor activity
GO:1900181 negative regulation of protein localization to nucleus
GO:1901675 negative regulation of histone H3-K27 acetylation
GO:1903351 cellular response to dopamine
GO:2000678 negative regulation of transcription regulatory region DNA binding

Diseases

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Interactions

95 interactions

InteractorPartnerSourcesPublicationsLink
Sin3aSuds3BioGRID, IntAct11909966 15489224 details
Sin3aSap30IntAct9702189 details
Sin3aSap25IntAct16449650 details
Sin3aHTTBioGRID10823891 details
Sin3aMXD1BioGRID10551834 11101889 details
Sin3aRESTBioGRID10570134 details
Sin3aCOPS2BioGRID10207062 details
Sin3aSAP18BioGRID11960000 details
Sin3aMNTBioGRID10918583 details
Sin3aAdd1BioGRID17074803 details
Sin3aTrp53BioGRID20211142 details
Sin3aKlf13BioGRID11477107 details
Sin3aKLF1BioGRID11287616 details
Sin3aELK1BioGRID11283259 details
Sin3aSFPQBioGRID11259580 details
Sin3aSMAD3BioGRID10575014 details
Sin3aSKILBioGRID10049357 details
Sin3aRB1BioGRID9988677 details
Sin3aDdx20BioGRID12007404 details
Sin3aCebpbBioGRID21521687 details
Sin3aDach1IntAct12130660 details
Sin3aHdac2BioGRID, DIP, IntAct, MINT15696166 16109738 18454139 19424149 20404188 24240174 details
Sin3aArid1aBioGRID, MINT17255939 details
Sin3aPA2G4IntAct16254079 details
Sin3aHDAC9UniProt12590135 details
Sin3aSox2BioGRID, IntAct19139101 31077711 details
Sin3aHdac1BioGRID, DIP, MINT10409740 10688671 11302704 16103876 16109738 19424149 20404188 21448134 21454521 24240174 details
Sin3aNanogBioGRID, MINT18454139 23892456 details
Sin3aMYCIntAct24951594 details
Sin3aMecp2BioGRID, DIP, MINT19602036 22119903 23770565 details
Sin3aIKZF1BioGRID10357820 details
Sin3aTal1BioGRID10688671 11118214 details
Sin3aSufuBioGRID11960000 details
Sin3aGLI1BioGRID11960000 details
Sin3aSmad4BioGRID17226765 details
Sin3aGatad2aBioGRID18454139 details
Sin3aSNAI1BioGRID14673164 28892081 details
Sin3aSNAI2BioGRID14673164 details
Sin3aSNAI3BioGRID14673164 details
Sin3aSp3BioGRID16109738 details
Sin3aMntBioGRID16103876 details
Sin3aSin3bBioGRID16103876 details
Sin3aTP53BioGRID11313951 details
Sin3aTBPBioGRID11313951 details
Sin3aSpi1BioGRID21518930 details
Sin3aGon4lBioGRID21454521 details
Sin3aYy1BioGRID21454521 details
Sin3aApex1BioGRID22441348 details
Sin3aPer2BioGRID21680841 details
Sin3aSfpqBioGRID21680841 details
Sin3aPer1BioGRID21680841 details
Sin3aEtv6BioGRID12527908 details
Sin3aKlf11BioGRID15300592 details
Sin3aTet2BioGRID21490601 details
Sin3aL3mbtl2BioGRID22770845 details
Sin3aKdm5bBioGRID, MINT21448134 details
Sin3aTfcp2l1BioGRID, IntAct20362541 details
Sin3aING1BioGRID, IntAct26496610 details
Sin3aGOLGA1BioGRID, IntAct26496610 details
Sin3aRBBP7BioGRID, IntAct26496610 details
Sin3aBRMS1LBioGRID, IntAct26496610 details
Sin3aNCOR1BioGRID, IntAct26496610 details
Sin3aHDAC1BioGRID, IntAct26496610 details
Sin3aARID4ABioGRID, IntAct26496610 details
Sin3aSINHCAFBioGRID, IntAct26496610 details
Sin3aSORBS3BioGRID, IntAct26496610 details
Sin3aSAP30BioGRID, IntAct26496610 details
Sin3aSUDS3BioGRID, IntAct26496610 details
Sin3aMECP2DIP23770565 details
Sin3aElf5BioGRID26584622 details
Sin3aBRMS1BioGRID26496610 details
Sin3aSAP130BioGRID26496610 details
Sin3aChaf1aBioGRID26365490 details
Sin3aCebpaBioGRID26167872 details
Sin3aArnt2BioGRID32325033 details
Sin3aCenpeBioGRID32325033 details
Sin3aDeaf1BioGRID32325033 details
Sin3aEfcab6BioGRID32325033 details
Sin3aNr4a3BioGRID32325033 details
Sin3aRbl1BioGRID32325033 details
Sin3aRbl2BioGRID32325033 details
Sin3aSatb1BioGRID32325033 details
Sin3aArntBioGRID32325033 details
Sin3aEp300BioGRID32325033 details
Sin3aEpas1BioGRID32325033 details
Sin3aFosBioGRID32325033 details
Sin3aKif4BioGRID32325033 details
Sin3aLdb2BioGRID32325033 details
Sin3aSmarca5BioGRID32325033 details
Sin3aSmc2BioGRID32325033 details
Sin3aTcf7l2BioGRID32325033 details
Sin3aCfdBioGRID30550785 details
Sin3aFndc5BioGRID30550785 details
Sin3aFoxp3IntAct24944246 details
Sin3aUnkBioGRID25737280 details