Entity Details

Primary name Six2
Entity type gene
Source Source Link

Details

PrimaryID20472
RefseqGene
SymbolSix2
Namesine oculis-related homeobox 2
Chromosome17
Location17 55.72 cM
TaxID10090
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-27
ModificationDate2021-06-23

Ontological Relatives

UniProt IDsSIX2_MOUSE

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001656 metanephros development
GO:0001822 kidney development
GO:0002062 chondrocyte differentiation
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006606 protein import into nucleus
GO:0007501 mesodermal cell fate specification
GO:0008134 transcription factor binding
GO:0008283 cell population proliferation
GO:0009948 anterior/posterior axis specification
GO:0016477 cell migration
GO:0030278 regulation of ossification
GO:0032330 regulation of chondrocyte differentiation
GO:0042474 middle ear morphogenesis
GO:0043565 sequence-specific DNA binding
GO:0044877 protein-containing complex binding
GO:0045596 negative regulation of cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048557 embryonic digestive tract morphogenesis
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048704 embryonic skeletal system morphogenesis
GO:0072006 nephron development
GO:0072028 nephron morphogenesis
GO:0072038 mesenchymal stem cell maintenance involved in nephron morphogenesis
GO:0072137 condensed mesenchymal cell proliferation
GO:0072161 mesenchymal cell differentiation involved in kidney development
GO:0090189 regulation of branching involved in ureteric bud morphogenesis
GO:0097168 mesenchymal stem cell proliferation
GO:1902732 positive regulation of chondrocyte proliferation
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
Six2Eya1BioGRID, IntAct, UniProt11734542 11950062 16024294 20956555 details